Recent data on the cerebellum require new models and theories.
Cognition
Credit assignment
Long-term depression
Long-term potentiation
Marr-Albus model
Purkinje neuron
Recurrent connection
Reward
Supervised learning
Journal
Current opinion in neurobiology
ISSN: 1873-6882
Titre abrégé: Curr Opin Neurobiol
Pays: England
ID NLM: 9111376
Informations de publication
Date de publication:
10 2023
10 2023
Historique:
received:
09
05
2023
revised:
22
07
2023
accepted:
23
07
2023
medline:
11
9
2023
pubmed:
18
8
2023
entrez:
17
8
2023
Statut:
ppublish
Résumé
The cerebellum has been a popular topic for theoretical studies because its structure was thought to be simple. Since David Marr and James Albus related its function to motor skill learning and proposed the Marr-Albus cerebellar learning model, this theory has guided and inspired cerebellar research. In this review, we summarize the theoretical progress that has been made within this framework of error-based supervised learning. We discuss the experimental progress that demonstrates more complicated molecular and cellular mechanisms in the cerebellum as well as new cell types and recurrent connections. We also cover its involvement in diverse non-motor functions and evidence of other forms of learning. Finally, we highlight the need to explain these new experimental findings into an integrated cerebellar model that can unify its diverse computational functions.
Identifiants
pubmed: 37591124
pii: S0959-4388(23)00090-9
doi: 10.1016/j.conb.2023.102765
pii:
doi:
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
102765Subventions
Organisme : NINDS NIH HHS
ID : R35 NS097343
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH046742
Pays : United States
Informations de copyright
Copyright © 2023 The Author(s). Published by Elsevier Ltd.. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.