An ultrasensitive ratiometric electrochemical aptasensor based on metal-organic frameworks and nanoflower-like Bi

Humans Metal-Organic Frameworks Receptor, ErbB-2 Biomarkers, Tumor
Bi(2)CuO(4) Breast cancer HER2 MOFs Ratiometric electrochemical aptasensor

Journal

Bioelectrochemistry (Amsterdam, Netherlands)
ISSN: 1878-562X
Titre abrégé: Bioelectrochemistry
Pays: Netherlands
ID NLM: 100953583

Informations de publication

Date de publication:
Dec 2023
Historique:
received: 17 06 2023
revised: 28 07 2023
accepted: 06 08 2023
medline: 18 9 2023
pubmed: 18 8 2023
entrez: 17 8 2023
Statut: ppublish

Résumé

An ultra-sensitive ratiometric electrochemical aptasensor was constructed based on metal-organic frameworks (MOFs) and bimetallic oxides for the detection of the human epidermal growth factor receptor 2 (HER2), a breast cancer marker. The aluminum metal-organic framework (Al-MOF) and cerium-metal-organic framework (Ce-MOF) have higher specific surface area, which is conducive to load more aptamers or complementary DNA (cDNA), and realize the amplification of internal reference signal Fc. Furthermore, nanoflower-like bismuth copper oxide (Bi

Identifiants

DOI: 10.1016/j.bioelechem.2023.108542 PMID: 37591183
pubmed: 37591183
pii: S1567-5394(23)00179-2
doi: 10.1016/j.bioelechem.2023.108542
pii:
doi:

Substances chimiques

ERBB2 protein, human EC 2.7.10.1
cupric oxide V1XJQ704R4
Metal-Organic Frameworks 0
Receptor, ErbB-2 EC 2.7.10.1
Biomarkers, Tumor 0
bismuth oxide A6I4E79QF1

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

108542

Informations de copyright

Copyright © 2023 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Ying Xu (Y)

Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing 400044, PR China.

Ya Zhang (Y)

Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing 400044, PR China.

Ning Li (N)

Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing 400044, PR China.

Siyi Yang (S)

Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing 400044, PR China.

Jian Chen (J)

Chongqing University Three Gorges Hospital, Chongqing 404000, PR China.

Jingzhou Hou (J)

Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing 400044, PR China; Postdoctoral Research Station, Chongqing University, Bioengineering College of Chongqing University, Chongqing 400044, PR China. Electronic address: houjz89329@163.com.

Changjun Hou (C)

Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing 400044, PR China; Chongqing Key Laboratory of Bio-perception & Intelligent Information Processing, School of Microelectronics and Communication Engineering, Chongqing University, Chongqing 400044, PR China. Electronic address: houcj@cqu.edu.cn.

Danqun Huo (D)

Key Laboratory for Biorheological Science and Technology of Ministry of Education, Bioengineering College of Chongqing University, Chongqing 400044, PR China; Postdoctoral Research Station, Chongqing University, Bioengineering College of Chongqing University, Chongqing 400044, PR China. Electronic address: huodq@cqu.edu.cn.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › An ultrasensitive ratiometric electrochemical...
questionsmedicales.fr › Structures macromoléculaires › Réseaux organométalliques › An ultrasensitive ratiometric electrochemical...
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Marqueurs biologiques tumoraux › Récepteur ErbB-2 › An ultrasensitive ratiometric electrochemical...
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Marqueurs biologiques tumoraux › An ultrasensitive ratiometric electrochemical...