The value of surgery in the treatment of gestational choriocarcinoma: A case report.
Chemoresistance
Gestational choriocarcinoma
Surgery-case report
Journal
International journal of surgery case reports
ISSN: 2210-2612
Titre abrégé: Int J Surg Case Rep
Pays: Netherlands
ID NLM: 101529872
Informations de publication
Date de publication:
Sep 2023
Sep 2023
Historique:
received:
14
06
2023
revised:
30
07
2023
accepted:
31
07
2023
medline:
18
8
2023
pubmed:
18
8
2023
entrez:
17
8
2023
Statut:
ppublish
Résumé
Gestational choriocarcinoma is a rare malignant trophoblastic tumor; it is characterized by its high metastatic potential and chemosensitivity. Hysterectomy also has a role in the management of this tumor. We report a rare case of gestational choriocarcinoma in a young woman initially classified as low risk (FIGO2), treated by surgery after chemoresistance to different chemotherapy protocols, marked by an excellent clinical and biochemical improvement. Gestational choriocarcinoma is a malignant tumor of the villous trophoblast, devoid of placental villi and vesicles.Despite the excellence of chemotherapy, surgery has a significant place in the treatment of gestational trophoblastic tumors. The most common modality of surgical treatment is total hysterectomy. Ovarian metastases are rare; the ovaries may be preserved depending on the age of the patients. The progress of recent years lies in the clarification of the therapeutic strategies used in the treatment of gestational trophoblastic tumors, in particular choriocarcinoma.
Identifiants
pubmed: 37591194
pii: S2210-2612(23)00763-0
doi: 10.1016/j.ijscr.2023.108634
pmc: PMC10436163
pii:
doi:
Types de publication
Case Reports
Langues
eng
Pagination
108634Informations de copyright
Copyright © 2023. Published by Elsevier Ltd.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare having no conflicts of interest for this article.