The value of surgery in the treatment of gestational choriocarcinoma: A case report.

Chemoresistance Gestational choriocarcinoma Surgery-case report

Journal

International journal of surgery case reports
ISSN: 2210-2612
Titre abrégé: Int J Surg Case Rep
Pays: Netherlands
ID NLM: 101529872

Informations de publication

Date de publication:
Sep 2023
Historique:
received: 14 06 2023
revised: 30 07 2023
accepted: 31 07 2023
medline: 18 8 2023
pubmed: 18 8 2023
entrez: 17 8 2023
Statut: ppublish

Résumé

Gestational choriocarcinoma is a rare malignant trophoblastic tumor; it is characterized by its high metastatic potential and chemosensitivity. Hysterectomy also has a role in the management of this tumor. We report a rare case of gestational choriocarcinoma in a young woman initially classified as low risk (FIGO2), treated by surgery after chemoresistance to different chemotherapy protocols, marked by an excellent clinical and biochemical improvement. Gestational choriocarcinoma is a malignant tumor of the villous trophoblast, devoid of placental villi and vesicles.Despite the excellence of chemotherapy, surgery has a significant place in the treatment of gestational trophoblastic tumors. The most common modality of surgical treatment is total hysterectomy. Ovarian metastases are rare; the ovaries may be preserved depending on the age of the patients. The progress of recent years lies in the clarification of the therapeutic strategies used in the treatment of gestational trophoblastic tumors, in particular choriocarcinoma.

Identifiants

pubmed: 37591194
pii: S2210-2612(23)00763-0
doi: 10.1016/j.ijscr.2023.108634
pmc: PMC10436163
pii:
doi:

Types de publication

Case Reports

Langues

eng

Pagination

108634

Informations de copyright

Copyright © 2023. Published by Elsevier Ltd.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare having no conflicts of interest for this article.

Auteurs

Younes Bencherifi (Y)

Department of Gynecology and Obstetrics, University Hospital Center Ibn Rochd, Casablanca, Morocco; Faculty of Medecine and Pharmacy, Hassan II University, 1 rue des hôpitaux, Casablanca, Morocco.

Imane El Abbassi (IE)

Department of Gynecology and Obstetrics, University Hospital Center Ibn Rochd, Casablanca, Morocco; Faculty of Medecine and Pharmacy, Hassan II University, 1 rue des hôpitaux, Casablanca, Morocco. Electronic address: imane.mammeri.im@gmail.com.

Douha El Karoini (DE)

Department of Gynecology and Obstetrics, University Hospital Center Ibn Rochd, Casablanca, Morocco; Faculty of Medecine and Pharmacy, Hassan II University, 1 rue des hôpitaux, Casablanca, Morocco.

Mohammed Ennachit (M)

Department of Gynecology and Obstetrics, University Hospital Center Ibn Rochd, Casablanca, Morocco; Faculty of Medecine and Pharmacy, Hassan II University, 1 rue des hôpitaux, Casablanca, Morocco.

Mustapha Benhessou (M)

Department of Gynecology and Obstetrics, University Hospital Center Ibn Rochd, Casablanca, Morocco; Faculty of Medecine and Pharmacy, Hassan II University, 1 rue des hôpitaux, Casablanca, Morocco.

Mohammed El Kerroumi (ME)

Department of Gynecology and Obstetrics, University Hospital Center Ibn Rochd, Casablanca, Morocco; Faculty of Medecine and Pharmacy, Hassan II University, 1 rue des hôpitaux, Casablanca, Morocco.

Classifications MeSH