The sulfonadyns: a class of aryl sulfonamides inhibiting dynamin I GTPase and clathrin mediated endocytosis are anti-seizure in animal models.
Journal
RSC medicinal chemistry
ISSN: 2632-8682
Titre abrégé: RSC Med Chem
Pays: England
ID NLM: 101759460
Informations de publication
Date de publication:
16 Aug 2023
16 Aug 2023
Historique:
received:
11
10
2022
accepted:
15
04
2023
pmc-release:
26
04
2024
medline:
18
8
2023
pubmed:
18
8
2023
entrez:
18
8
2023
Statut:
epublish
Résumé
We show that dansylcadaverine (1) a known in-cell inhibitor of clathrin mediated endocytosis (CME), moderately inhibits dynamin I (dynI) GTPase activity (IC
Identifiants
pubmed: 37593570
doi: 10.1039/d2md00371f
pii: d2md00371f
pmc: PMC10429932
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1492-1511Informations de copyright
This journal is © The Royal Society of Chemistry.
Déclaration de conflit d'intérêts
The authors declare the following competing financial interest(s): we have entered into a commercial agreement with Abcam (Cambridge, UK) for the supply of some of our lead dynamin and clathrin inhibitors. This includes some of the compounds listed in this paper.
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