Prevalence and determinants of cardiovascular risk factors in Lesotho: a population-based survey.

diabetes dyslipidaemia hypertension non-communicable diseases overweight tobacco

Journal

International health
ISSN: 1876-3405
Titre abrégé: Int Health
Pays: England
ID NLM: 101517095

Informations de publication

Date de publication:
18 Aug 2023
Historique:
received: 04 05 2023
revised: 17 07 2023
accepted: 20 07 2023
medline: 18 8 2023
pubmed: 18 8 2023
entrez: 18 8 2023
Statut: aheadofprint

Résumé

There are no recent data on the prevalence of cardiovascular risk factors (CVDRFs) in Lesotho. This study aims to assess the prevalence of CVDRFs and their determinants. We conducted a household-based, cross-sectional survey among adults ≥18 y of age in 120 randomly sampled clusters in two districts. Among 6061 participants, 52.2% were female and their median age was 39 y (interquartile range 27-58). The overall prevalence of overweight, diabetes, elevated blood pressure (BP) and tobacco use was 39.9%, 5.3%, 21.6% and 24.9%, respectively. Among participants, 34.6% had none, 45.2% had one and 20.2% had two or more CVDRFs. Women were more likely to have two or more CVDRFs (20.7% vs 12.3%). Overall, 7.5% of participants had elevated total cholesterol, 52.7% had low high-density lipoprotein cholesterol and 1.6% had elevated low-density lipoprotein cholesterol. Among younger participants (18-29 y), 16.1% reported tobacco use, 28.6% were overweight, 1.5% had diabetes and 3.5% had elevated BP. Household wealth positively correlated with the prevalence of elevated BP, overweight and diabetes, whereas tobacco use was higher among people in the lowest three wealth quintiles. CVDRFs are highly prevalent in Lesotho across age and sex groups, underlining the importance of strengthening prevention and care programs in Lesotho and similar settings in southern Africa.

Sections du résumé

BACKGROUND BACKGROUND
There are no recent data on the prevalence of cardiovascular risk factors (CVDRFs) in Lesotho. This study aims to assess the prevalence of CVDRFs and their determinants.
METHODS METHODS
We conducted a household-based, cross-sectional survey among adults ≥18 y of age in 120 randomly sampled clusters in two districts.
RESULTS RESULTS
Among 6061 participants, 52.2% were female and their median age was 39 y (interquartile range 27-58). The overall prevalence of overweight, diabetes, elevated blood pressure (BP) and tobacco use was 39.9%, 5.3%, 21.6% and 24.9%, respectively. Among participants, 34.6% had none, 45.2% had one and 20.2% had two or more CVDRFs. Women were more likely to have two or more CVDRFs (20.7% vs 12.3%). Overall, 7.5% of participants had elevated total cholesterol, 52.7% had low high-density lipoprotein cholesterol and 1.6% had elevated low-density lipoprotein cholesterol. Among younger participants (18-29 y), 16.1% reported tobacco use, 28.6% were overweight, 1.5% had diabetes and 3.5% had elevated BP. Household wealth positively correlated with the prevalence of elevated BP, overweight and diabetes, whereas tobacco use was higher among people in the lowest three wealth quintiles.
CONCLUSIONS CONCLUSIONS
CVDRFs are highly prevalent in Lesotho across age and sex groups, underlining the importance of strengthening prevention and care programs in Lesotho and similar settings in southern Africa.

Identifiants

pubmed: 37593886
pii: 7245757
doi: 10.1093/inthealth/ihad058
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Swiss National Science Foundation
ID : PCEFP3_181355
Pays : Switzerland

Informations de copyright

© The Author(s) 2023. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene.

Auteurs

Lucia González Fernández (L)

Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.
Department of Medicine, Swiss Tropical and Public Health Institute, Allschwil, Basel, 4051, Switzerland.
University of Basel, Basel, Switzerland.
SolidarMed, Partnerships for Health, Luzern, Switzerland.

Emmanuel Firima (E)

Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.
Department of Medicine, Swiss Tropical and Public Health Institute, Allschwil, Basel, 4051, Switzerland.
University of Basel, Basel, Switzerland.

Ravi Gupta (R)

SolidarMed, Partnerships for Health, Maseru, Lesotho.

Mamoronts'ane Pauline Sematle (MP)

SolidarMed, Partnerships for Health, Maseru, Lesotho.

Makhebe Khomolishoele (M)

SolidarMed, Partnerships for Health, Maseru, Lesotho.

Manthabiseng Molulela (M)

SolidarMed, Partnerships for Health, Maseru, Lesotho.

Matumaole Bane (M)

SolidarMed, Partnerships for Health, Maseru, Lesotho.

Raphaela Meli (R)

SolidarMed, Partnerships for Health, Luzern, Switzerland.

Mosa Tlahani (M)

Mokhotlong District Health Management Team, Mokhotlong, Ministry of Health Lesotho.

Tristan Lee (T)

Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.
Department of Medicine, Swiss Tropical and Public Health Institute, Allschwil, Basel, 4051, Switzerland.
University of Basel, Basel, Switzerland.

Frédérique Chammartin (F)

Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.
University of Basel, Basel, Switzerland.

Felix Geber (F)

Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.
Department of Medicine, Swiss Tropical and Public Health Institute, Allschwil, Basel, 4051, Switzerland.
University of Basel, Basel, Switzerland.

Thabo Ishmael Lejone (TI)

Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.
University of Basel, Basel, Switzerland.

Irene Ayakaka (I)

SolidarMed, Partnerships for Health, Maseru, Lesotho.

Maja Weisser (M)

Department of Medicine, Swiss Tropical and Public Health Institute, Allschwil, Basel, 4051, Switzerland.
University of Basel, Basel, Switzerland.
Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland.

Alain Amstutz (A)

Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.
University of Basel, Basel, Switzerland.

Niklaus Daniel Labhardt (ND)

Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.
University of Basel, Basel, Switzerland.

Classifications MeSH