Implementation of Brachytherapy for Patients With Cervical Cancer in Ethiopia: A 3-Year Practice Report.


Journal

JCO global oncology
ISSN: 2687-8941
Titre abrégé: JCO Glob Oncol
Pays: United States
ID NLM: 101760170

Informations de publication

Date de publication:
08 2023
Historique:
medline: 21 8 2023
pubmed: 18 8 2023
entrez: 18 8 2023
Statut: ppublish

Résumé

Although cervical cancer is the second most commonly diagnosed cancer in Ethiopia, brachytherapy (BT) was not a component in patient treatment until 2015. The purpose of this study was to identify the patterns of utilization as well as to describe the practice of BT in Ethiopia. A retrospective descriptive data analysis of 138 patients with cervical cancer treated with a curative potential using BT from 2015 to 2018 at Tikur Anbassa Specialized Hospital, which housed the only BT facility in Ethiopia during the study period. During the first 3-year period of BT service commencement, each year n = 37, n = 36, and n = 65 patients with cervical cancer were treated, respectively, with curative intention treatment. The median age of these 138 patients was 50 years (range, 22-75). All the patients were in International Federation of Gynecology and Obstetrics stage Ib-IIIb group, and stage IIb (66.4%) was the predominant. Majority (79%) of the patients were treated primarily with radiotherapy (RT), while 21% received RT after surgery. More than half of these patients (62%) received a total RT dose of 82 Gy in equivalent dose in 2 Gy fractions (EQD2), while the rest received a dose ranging from 76 to 86 Gy. Concurrent cisplatin with RT was given only for 36% of the patients for undocumented reasons. The overall treatment time including both external-beam RT and BT was greater than 8 weeks in 21% of the patients. The utilization of BT service increased gradually and BT enabled the delivery of a higher RT dose to patients with cervical cancer (mostly stage IIB). However, there was protracted treatment duration and low concurrent chemotherapy utilization.

Identifiants

pubmed: 37595167
doi: 10.1200/GO.22.00407
pmc: PMC10581656
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2200407

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Auteurs

Yitbarek M Kibret (YM)

Oncology Department, Yekatit 12 Hospital Medical College, Addis Ababa, Ethiopia.
Global Health Working Group, Martin-Luther-University Halle-Wittenberg, Germany.

Wondemagegnehu Tigeneh (W)

Oncology Department, Addis Ababa University, Addis Ababa, Ethiopia.

Ahmedin Jemal (A)

Surveillance and Health Service Research, American Cancer Society, Atlanta, GA.

Eva J Kantelhardt (EJ)

Global Health Working Group, Martin-Luther-University Halle-Wittenberg, Germany.
Department of Gynaecology, Martin-Luther-University Halle-Wittenberg, Halle, Germany.

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Classifications MeSH