Dynamics and spatial organization of Kv1.3 at the immunological synapse of human CD4+ T cells.
Journal
Biophysical journal
ISSN: 1542-0086
Titre abrégé: Biophys J
Pays: United States
ID NLM: 0370626
Informations de publication
Date de publication:
18 Aug 2023
18 Aug 2023
Historique:
received:
12
05
2023
revised:
27
07
2023
accepted:
14
08
2023
pubmed:
19
8
2023
medline:
19
8
2023
entrez:
19
8
2023
Statut:
aheadofprint
Résumé
Formation of the immunological synapse (IS) is a key event during initiation of an adaptive immune response to a specific antigen. During this process, a T cell and an antigen presenting cell form a stable contact that allows the T cell to integrate both internal and external stimuli in order to decide whether to activate. The threshold for T cell activation depends on the strength and frequency of the calcium (Ca
Identifiants
pubmed: 37596785
pii: S0006-3495(23)00511-8
doi: 10.1016/j.bpj.2023.08.011
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2023 Biophysical Society. Published by Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of interests Authors declare that they have no competing interests.