The mitochondria-targeted sulfide delivery molecule attenuates drugs-induced gastropathy. Involvement of heme oxygenase pathway.

Rats Animals Rats, Wistar Heme Oxygenase (Decyclizing) / genetics Sulfides Phosphorylation Anti-Inflammatory Agents, Non-Steroidal Aspirin
Gastric mucosa Heme oxygenase Hydrogen sulfide Mitochondria Non-steroidal anti-inflammatory drugs

Journal

Redox biology
ISSN: 2213-2317
Titre abrégé: Redox Biol
Pays: Netherlands
ID NLM: 101605639

Informations de publication

Date de publication:
10 2023
Historique:
received: 14 07 2023
revised: 07 08 2023
accepted: 11 08 2023
medline: 13 9 2023
pubmed: 20 8 2023
entrez: 19 8 2023
Statut: ppublish

Résumé

Hydrogen sulfide (H

Identifiants

DOI: 10.1016/j.redox.2023.102847 PMID: 37597422 PMC: PMC10458696
pubmed: 37597422
pii: S2213-2317(23)00248-3
doi: 10.1016/j.redox.2023.102847
pmc: PMC10458696
pii:
doi:

Substances chimiques

Heme Oxygenase (Decyclizing) EC 1.14.14.18
Sulfides 0
Anti-Inflammatory Agents, Non-Steroidal 0
Aspirin R16CO5Y76E

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

102847

Subventions

Organisme : Medical Research Council
ID : MR/M022706/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/S002626/1
Pays : United Kingdom

Informations de copyright

Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest These authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Matthew Whiteman reports a relationship with MitoRx Therapeutics that includes: equity or stocks. Roberta Torregrossa reports a relationship with MitoRx Therapeutics that includes: employment. Matthew Whiteman has patents awarded and pending for the use of sulfide-delivery molecules.

Auteurs

Katarzyna Magierowska (K)

Department of Physiology, Jagiellonian University Medical College, Cracow, Poland.

Dagmara Wójcik-Grzybek (D)

Department of Physiology, Jagiellonian University Medical College, Cracow, Poland.

Edyta Korbut (E)

Department of Physiology, Jagiellonian University Medical College, Cracow, Poland.

Dominik Bakalarz (D)

Department of Physiology, Jagiellonian University Medical College, Cracow, Poland; Department of Forensic Toxicology, Institute of Forensic Research, Cracow, Poland.

Grzegorz Ginter (G)

Department of Physiology, Jagiellonian University Medical College, Cracow, Poland.

Aleksandra Danielak (A)

Department of Physiology, Jagiellonian University Medical College, Cracow, Poland.

Sławomir Kwiecień (S)

Department of Physiology, Jagiellonian University Medical College, Cracow, Poland.

Anna Chmura (A)

Department of Physiology, Jagiellonian University Medical College, Cracow, Poland.

Roberta Torregrossa (R)

University of Exeter Medical School, University of Exeter, Exeter, United Kingdom.

Matthew Whiteman (M)

University of Exeter Medical School, University of Exeter, Exeter, United Kingdom.

Marcin Magierowski (M)

Department of Physiology, Jagiellonian University Medical College, Cracow, Poland. Electronic address: m.magierowski@uj.edu.pl.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › The mitochondria-targeted sulfide delivery...
questionsmedicales.fr › Eucaryotes › Animaux › The mitochondria-targeted sulfide delivery...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Rat Wistar › The mitochondria-targeted sulfide delivery...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Oxygénases › Mixed function oxygenases › Heme oxygenase (decyclizing) › The mitochondria-targeted sulfide delivery...
questionsmedicales.fr › Composés chimiques organiques › Composés du soufre › Sulfures › The mitochondria-targeted sulfide delivery...
questionsmedicales.fr › Métabolisme › Phosphorylation › The mitochondria-targeted sulfide delivery...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antirhumatismaux › Anti-inflammatoires non stéroïdiens › The mitochondria-targeted sulfide delivery...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures aromatiques › Dérivés du benzène › Phénols › Hydroxybenzoates › Salicylates › Acide acétylsalicylique › The mitochondria-targeted sulfide delivery...