Anti-pathogenicity of Acanthus ilicifolius leaf extracts against A. hydrophila infection in Labeo rohita fingerlings.
Acanthus ilicifolius
Antibacterial activity
Antioxidant activity
GC–MS
L. rohita
Journal
AMB Express
ISSN: 2191-0855
Titre abrégé: AMB Express
Pays: Germany
ID NLM: 101561785
Informations de publication
Date de publication:
20 Aug 2023
20 Aug 2023
Historique:
received:
01
02
2023
accepted:
10
08
2023
medline:
20
8
2023
pubmed:
20
8
2023
entrez:
20
8
2023
Statut:
epublish
Résumé
Antibiotic resistance has become one of the inevitable barrier in aquaculture disease management. Herbal drugs has evolved to be the novel ways of combating drug resistant pathogens. In the current investigation, leaf extracts of mangrove plant, Acanthus ilicifolius were assessed for in vitro studies, among the selected four extracts, methanol extract has expressed highest antibacterial activity against P .aeruginosa (4 ± 0.3 mm), A. hydrophila (5.9 ± 0.5 mm), S. aureus (3.5 ± 0.7 mm) and B. subtilis (2.9 ± 0.5 mm) and antioxidant activity, DPPH (81.3 ± 1.0 AAEµg/ml) and FRAP (139.1 ± 1.5 AAEµg/ml).TPC and TFC were higher in the methanolic extract and has exhibited positive correlation with both DPPH and FRAP assays. Considering the in vitro efficiency, methanol extract was purified successively by column and thin layer chromatography and characterisation by GC-MS unveiled the presence of 2-Propanethiol, Trimethylphosphine, Pentanoyl chloride, Dimethylhydroxymethylphosphine and Propanedinitrile, ethylidene. A. hydrophila infected L. rohita fingerlings has survival percentage 81% and 94% in extract treated groups over 0% in negative control and 71% in positive control.
Identifiants
pubmed: 37598392
doi: 10.1186/s13568-023-01595-y
pii: 10.1186/s13568-023-01595-y
pmc: PMC10440336
doi:
Types de publication
Journal Article
Langues
eng
Pagination
86Informations de copyright
© 2023. Springer-Verlag GmbH Germany, part of Springer Nature.
Références
Front Pharmacol. 2021 Mar 10;12:584019
pubmed: 33790782
Anal Biochem. 1996 Jul 15;239(1):70-6
pubmed: 8660627
J Biol Chem. 1972 May 25;247(10):3170-5
pubmed: 4623845
Appl Microbiol. 1967 Mar;15(2):417-21
pubmed: 6029837
AMB Express. 2021 Oct 8;11(1):135
pubmed: 34623537
Plants (Basel). 2021 Jan 28;10(2):
pubmed: 33525519
J Infect Public Health. 2021 Dec;14(12):1927-1934
pubmed: 34756814
Methods Enzymol. 1984;105:121-6
pubmed: 6727660
J Agric Food Chem. 2004 Dec 29;52(26):8151-4
pubmed: 15612810
Comp Biochem Physiol C Toxicol Pharmacol. 2006 Aug;143(4):492-8
pubmed: 16765096
PLoS One. 2020 May 13;15(5):e0232205
pubmed: 32401792
Asian Pac J Trop Biomed. 2013 Jan;3(1):17-21
pubmed: 23570011
Microbiol Res. 2014 Jul-Aug;169(7-8):483-95
pubmed: 24582778
J Med Chem. 2019 Sep 12;62(17):7751-7768
pubmed: 31386365
Anal Biochem. 1976 May 7;72:248-54
pubmed: 942051
ChemMedChem. 2018 Aug 10;13(15):1549-1554
pubmed: 29920962
J Ethnopharmacol. 1988 Jul-Aug;23(2-3):127-49
pubmed: 3057288
J Biomol Struct Dyn. 2021 Apr;39(7):2376-2386
pubmed: 32216608
Indian J Pharm Sci. 2010 Mar;72(2):167-72
pubmed: 20838519
Heliyon. 2019 Aug 26;5(8):e02233
pubmed: 31485504
J Agric Food Chem. 2020 Oct 28;68(43):11908-11919
pubmed: 32970417
AAPS J. 2015 May;17(3):513-24
pubmed: 25700799
Pathogens. 2021 Feb 04;10(2):
pubmed: 33557078
J Ethnopharmacol. 2022 Jul 15;293:115271
pubmed: 35430290
Fish Shellfish Immunol. 2022 Jul;126:73-83
pubmed: 35609759
Clin Infect Dis. 2009 Oct 15;49(8):1248-53
pubmed: 19772389
Sci Rep. 2020 Oct 2;10(1):16438
pubmed: 33009462
Environ Pollut. 2017 Apr;223:161-169
pubmed: 28131482
Asian Pac J Trop Med. 2011 Jul;4(7):523-5
pubmed: 21803301
Afr J Tradit Complement Altern Med. 2011;8(1):1-10
pubmed: 22238476