Safety of Lumason® (SonoVue®) in special populations and critically ill patients.
Lumason
SonoVue
echocardiography
safety
ultrasound contrast agents
Journal
Frontiers in cardiovascular medicine
ISSN: 2297-055X
Titre abrégé: Front Cardiovasc Med
Pays: Switzerland
ID NLM: 101653388
Informations de publication
Date de publication:
2023
2023
Historique:
received:
13
06
2023
accepted:
13
07
2023
medline:
21
8
2023
pubmed:
21
8
2023
entrez:
21
8
2023
Statut:
epublish
Résumé
Evidence for the safe use of Lumason® (SonoVue®), an ultrasound enhancing agent (UEA), in special patient populations is critical to enable healthcare professionals to make informed decisions concerning its use in such patients. Herein, we provide insight on the safety and tolerability of Lumason® in special patient populations. Findings are presented from clinical pharmacology studies conducted in patients with compromised cardiopulmonary conditions, from a retrospective study performed in critically ill patients, and from post-marketing surveillance data from over 20 years of market use of Lumason® (SonoVue®). No detrimental effects of Lumason® on cardiac electrophysiology were observed in patients with coronary artery disease (CAD), and no significant effects on pulmonary hemodynamics were noted in patients with pulmonary hypertension or congestive heart failure. Similarly, no effects on several assessments of pulmonary function (e.g., FVC) were observed in patients with chronic obstructive pulmonary disease (COPD), and no clinically meaningful changes in O
Identifiants
pubmed: 37600063
doi: 10.3389/fcvm.2023.1225654
pmc: PMC10433219
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1225654Informations de copyright
© 2023 Filippone, Kirchin, Monteith, Storto and Spinazzi.
Déclaration de conflit d'intérêts
AF and MK are employed by Bracco Imaging SpA and JM, MS and AS are employed by Bracco Diagnostics Inc.
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