Effect of Circular Stapler Diameter on Anastomotic Leakage Rate and Stenosis After Open Total Gastrectomy With Esophagojejunostomy: A Substantive Retrospective Propensity Score Matched Series.

anastomosis anastomotic leakage anastomotic stenosis esophagojejunostomy gastrectomy surgical stapler

Journal

Annals of surgery open : perspectives of surgical history, education, and clinical approaches
ISSN: 2691-3593
Titre abrégé: Ann Surg Open
Pays: United States
ID NLM: 101769928

Informations de publication

Date de publication:
Sep 2022
Historique:
received: 14 12 2021
accepted: 07 07 2022
medline: 21 8 2023
pubmed: 21 8 2023
entrez: 21 8 2023
Statut: epublish

Résumé

Anastomotic leakage (AL) and stenosis (AS) are two of the most severe postoperative complications after total gastrectomy with esophagojejunostomy. The stapler diameter can be chosen by the surgeon. Therefore, this study aims to assess the correlation between the stapler size as main independent variable as well as other different risk factors and AL and AS. We conducted a retrospective analysis of data from 356 patients who underwent open total gastrectomy between 2000 and 2018, mostly due to gastric cancer (96.9%). After propensity score matching the outcome parameters AL and AS were compared between the two stapler size groups. We also assessed different risk factors for AL and AS in cancer patients using multivariate analysis. Small circular stapler diameter (21/25 mm; n = 147 vs 28/29/31 mm; n = 209) was identified as a significant risk factor for the occurrence of AL (10% vs 4% for smaller vs larger staplers; The application of a larger circular stapler for esophagojejunostomy in open total gastrectomy shows significantly lower rates of AL and stenosis. Therefore, the largest possible stapler diameter should be applied.

Sections du résumé

Background UNASSIGNED
Anastomotic leakage (AL) and stenosis (AS) are two of the most severe postoperative complications after total gastrectomy with esophagojejunostomy. The stapler diameter can be chosen by the surgeon. Therefore, this study aims to assess the correlation between the stapler size as main independent variable as well as other different risk factors and AL and AS.
Methods UNASSIGNED
We conducted a retrospective analysis of data from 356 patients who underwent open total gastrectomy between 2000 and 2018, mostly due to gastric cancer (96.9%). After propensity score matching the outcome parameters AL and AS were compared between the two stapler size groups. We also assessed different risk factors for AL and AS in cancer patients using multivariate analysis.
Results UNASSIGNED
Small circular stapler diameter (21/25 mm; n = 147 vs 28/29/31 mm; n = 209) was identified as a significant risk factor for the occurrence of AL (10% vs 4% for smaller vs larger staplers;
Conclusion UNASSIGNED
The application of a larger circular stapler for esophagojejunostomy in open total gastrectomy shows significantly lower rates of AL and stenosis. Therefore, the largest possible stapler diameter should be applied.

Identifiants

pubmed: 37601147
doi: 10.1097/AS9.0000000000000195
pmc: PMC10431426
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e195

Informations de copyright

Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc.

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Auteurs

Anke Mittelstädt (A)

From the Department of General and Visceral Surgery, Friedrich-Alexander University, Erlangen, Germany.

Helena Reitberger (H)

From the Department of General and Visceral Surgery, Friedrich-Alexander University, Erlangen, Germany.

Julia Fleischmann (J)

From the Department of General and Visceral Surgery, Friedrich-Alexander University, Erlangen, Germany.

Moustafa Elshafei (M)

Department of Bariatric and Metabolic Medicine, Clinic Northwest, Frankfurt, Germany.

Maximilian Brunner (M)

From the Department of General and Visceral Surgery, Friedrich-Alexander University, Erlangen, Germany.

Anna Anthuber (A)

From the Department of General and Visceral Surgery, Friedrich-Alexander University, Erlangen, Germany.

Christian Krautz (C)

From the Department of General and Visceral Surgery, Friedrich-Alexander University, Erlangen, Germany.

Marianna Lucio (M)

Research Unit Analytical BioGeoChemistry, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.

Susanne Merkel (S)

From the Department of General and Visceral Surgery, Friedrich-Alexander University, Erlangen, Germany.

Robert Grützmann (R)

From the Department of General and Visceral Surgery, Friedrich-Alexander University, Erlangen, Germany.

Georg F Weber (GF)

From the Department of General and Visceral Surgery, Friedrich-Alexander University, Erlangen, Germany.

Classifications MeSH