Cannabis Improves Clinical Outcomes and Quality of Life in Patients With Chronic Pouchitis.

cannabis ileoanal pouch anastomosis pouchitis quality of life ulcerative colitis

Journal

ACG case reports journal
ISSN: 2326-3253
Titre abrégé: ACG Case Rep J
Pays: United States
ID NLM: 101638398

Informations de publication

Date de publication:
Aug 2023
Historique:
received: 15 05 2023
accepted: 20 07 2023
medline: 21 8 2023
pubmed: 21 8 2023
entrez: 21 8 2023
Statut: epublish

Résumé

Many patients with ulcerative colitis after ileoanal pouch anastomosis report improvement of pouchitis with the use of cannabis. Nine patients with chronic pouchitis used 1 g/d of cannabis: 7 patients were male with average age 51 ± 16 years. Average partial pouchitis disease activity index were 11 (range 8-17), 6 (range 5-8), and 5 (range 4-8); endoscopic subscores were 7 .3 ± 2.3, 6 ± 1.1, and 4.4 ± 0.9; average bowel movements per day were 14 (range 8-20), 8 (range 2-13), and 10 (range 13-8); and quality of life increased from 72 ± 1 to 90 ± 16 and 97 ± 10 (

Identifiants

pubmed: 37601299
doi: 10.14309/crj.0000000000001131
pii: ACGCR-23-0416
pmc: PMC10435015
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e01131

Informations de copyright

© 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.

Références

Dis Colon Rectum. 2005 Aug;48(8):1542-9
pubmed: 15937625
Inflamm Bowel Dis. 2013 Aug;19(9):2001-10
pubmed: 23624887
J Crohns Colitis. 2021 Aug 2;15(8):1272-1278
pubmed: 33544128
PLoS One. 2021 Feb 11;16(2):e0246871
pubmed: 33571293
J Dig Dis. 2021 Oct;22(10):582-589
pubmed: 34431218
J Mol Med (Berl). 2009 Nov;87(11):1111-21
pubmed: 19690824
Mayo Clin Proc. 1994 May;69(5):409-15
pubmed: 8170189
Intest Res. 2021 Jan;19(1):1-11
pubmed: 33138344
Inflamm Bowel Dis. 2018 Mar 19;24(4):714-724
pubmed: 29538683
Gastroenterology. 2020 Feb;158(3):610-624.e13
pubmed: 31605691
Gut Liver. 2022 Jul 15;16(4):515-524
pubmed: 34670875
World J Gastroenterol. 2007 Nov 14;13(42):5598-604
pubmed: 17948934
Inflamm Bowel Dis. 2021 Jun 15;27(7):965-970
pubmed: 32944766
Crohns Colitis 360. 2020 Jul;2(3):otaa039
pubmed: 32744536

Auteurs

Timna Naftali (T)

Institute of Gastroenterology and Hepatology, Meir Medical Center, Kfar Saba, Israel.
Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Lihi Bar-Lev Schleider (L)

Soroka University Medical Center and Faculty of Health Sciences, Ben Gurion University of the Negev, Beersheba, Israel.

Hen Kayless (H)

Institute of Gastroenterology and Hepatology, Meir Medical Center, Kfar Saba, Israel.
Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Zohar Bromberg (Z)

Institute of Gastroenterology and Hepatology, Meir Medical Center, Kfar Saba, Israel.

Iris Dotan (I)

Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Division of Gastroenterology, Rabin Medical Center, Petah Tikva, Israel.

Efrat Broide (E)

Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Jecheskiel Sigi Gonczarowski Pediatric Gastroenterology Unit, Shamir (Assaf Harofeh) Medical Center, Zerifin, Israel.

Classifications MeSH