Menthol causes mitochondrial Ca
Cardiolipin
ER-Mito contact points
Mitochondrial Ca(2+)-influx
Mitochondrial temperature
Neuro-degeneration
ROS
Journal
Life sciences
ISSN: 1879-0631
Titre abrégé: Life Sci
Pays: Netherlands
ID NLM: 0375521
Informations de publication
Date de publication:
15 Oct 2023
15 Oct 2023
Historique:
received:
07
04
2023
revised:
07
08
2023
accepted:
17
08
2023
medline:
25
9
2023
pubmed:
22
8
2023
entrez:
21
8
2023
Statut:
ppublish
Résumé
Menthol is a small bioactive compound able to cause several physiological changes and has multiple molecular targets. Therefore, cellular response against menthol is complex, and still poorly understood. In this work, we used a human osteosarcoma cell line (Saos-2) and analysed the effect of menthol, especially in terms of cellular, subcellular and molecular aspects. We demonstrate that menthol causes increased mitochondrial Ca
Identifiants
pubmed: 37604353
pii: S0024-3205(23)00667-7
doi: 10.1016/j.lfs.2023.122032
pii:
doi:
Substances chimiques
Menthol
1490-04-6
Cardiolipins
0
Adenosine Triphosphate
8L70Q75FXE
Calcium
SY7Q814VUP
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
122032Informations de copyright
Copyright © 2023 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest All authors declare the existence of no conflict with this work. The funding bodies have no role in experiment design, data analysis, manuscript preparation or decision to publish this work.