Correlation of Ocular Plane-Wave Doppler With Optical Coherence Tomography Angiography in Preeclampsia.
blood flow
eye
optical coherence tomography angiography
plane-wave Doppler
preeclampsia
ultrasound
Journal
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
ISSN: 1550-9613
Titre abrégé: J Ultrasound Med
Pays: England
ID NLM: 8211547
Informations de publication
Date de publication:
Dec 2023
Dec 2023
Historique:
revised:
02
05
2023
received:
16
03
2023
accepted:
06
08
2023
medline:
23
11
2023
pubmed:
22
8
2023
entrez:
22
8
2023
Statut:
ppublish
Résumé
Preeclampsia (PE) is a severe complication of pregnancy characterized by hypertension, proteinuria and compromised fetal blood supply. The eye, like other end organs, is affected by this systemic condition, but unlike in other organs, ocular media transparency allows high-resolution optical visualization of the vascular structure of the retina. Our aim was to assess how ultrasound-determined ocular blood-flow correlates with vascular structure of the retina and choriocapillaris determined by optical coherence tomography angiography (OCTA). Plane-wave ultrasound and OCTA were performed on both eyes of 40 consecutive subjects consisting of normal controls (n = 11), mild PE (n = 5), severe PE (n = 17) and chronic or gestational hypertension (n = 7) within 72 hours following delivery. From ultrasound, we measured pulsatile flow velocity and resistance indices in the central retinal artery (CRA) and vein, the short posterior ciliary arteries (SPCAs) and choroid. From OCTA, we measured vascular density (VD) in the superficial, deep retina and choriocapillaris. We determined differences in Doppler and OCTA parameters among groups and correlations between ultrasound and OCTA. In severe PE, flow resistance was reduced with respect to controls. Flow velocity and resistance in the and SPCA were moderately correlated with VD in the choriocapillaris and peripapillary retina, but VD in PE did not differ significantly from controls. Although OCTA parameters were moderately correlated with Doppler ultrasound, OCTA did not demonstrate significant differences between PE and controls postpartum.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2815-2824Subventions
Organisme : NIH HHS
ID : P30 EY019007
Pays : United States
Organisme : NIH HHS
ID : R01 EY025215
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1TR001873
Pays : United States
Organisme : NIH HHS
ID : P30 EY019007
Pays : United States
Organisme : NIH HHS
ID : R01 EY025215
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1TR001873
Pays : United States
Informations de copyright
© 2023 American Institute of Ultrasound in Medicine.
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