Discovery of WLB-89462, a New Drug-like and Highly Selective σ

Animals Rats Amyloid beta-Peptides Ligands Neuroprotection Neuroprotective Agents / pharmacology

Journal

Journal of medicinal chemistry
ISSN: 1520-4804
Titre abrégé: J Med Chem
Pays: United States
ID NLM: 9716531

Informations de publication

Date de publication:
14 09 2023
Historique:
medline: 15 9 2023
pubmed: 23 8 2023
entrez: 22 8 2023
Statut: ppublish

Résumé

The synthesis and pharmacological activity of a new series of isoxazolylpyrimidines as sigma-2 receptor (σ

Identifiants

DOI: 10.1021/acs.jmedchem.3c01060 PMID: 37607512
pubmed: 37607512
doi: 10.1021/acs.jmedchem.3c01060
doi:

Substances chimiques

sigma-2 receptor 0
Amyloid beta-Peptides 0
Ligands 0
Neuroprotective Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

12499-12519

Auteurs

Ute Christmann (U)

Welab Barcelona, Parc Científic Barcelona, C/Baldiri Reixac 4-8,08028 Barcelona, Spain.

José Luis Díaz (JL)

Welab Barcelona, Parc Científic Barcelona, C/Baldiri Reixac 4-8,08028 Barcelona, Spain.
ORCID: 0000-0001-8812-4689

Rosalia Pascual (R)

Welab Barcelona, Parc Científic Barcelona, C/Baldiri Reixac 4-8,08028 Barcelona, Spain.

Magda Bordas (M)

Welab Barcelona, Parc Científic Barcelona, C/Baldiri Reixac 4-8,08028 Barcelona, Spain.

Inés Álvarez (I)

Welab Barcelona, Parc Científic Barcelona, C/Baldiri Reixac 4-8,08028 Barcelona, Spain.

Xavier Monroy (X)

Welab Barcelona, Parc Científic Barcelona, C/Baldiri Reixac 4-8,08028 Barcelona, Spain.

Mónica Porras (M)

Welab Barcelona, Parc Científic Barcelona, C/Baldiri Reixac 4-8,08028 Barcelona, Spain.

Sandra Yeste (S)

Welab Barcelona, Parc Científic Barcelona, C/Baldiri Reixac 4-8,08028 Barcelona, Spain.

Raquel F Reinoso (RF)

Welab Barcelona, Parc Científic Barcelona, C/Baldiri Reixac 4-8,08028 Barcelona, Spain.

Manuel Merlos (M)

Welab Barcelona, Parc Científic Barcelona, C/Baldiri Reixac 4-8,08028 Barcelona, Spain.

José Miguel Vela (JM)

Welab Barcelona, Parc Científic Barcelona, C/Baldiri Reixac 4-8,08028 Barcelona, Spain.

Carmen Almansa (C)

Welab Barcelona, Parc Científic Barcelona, C/Baldiri Reixac 4-8,08028 Barcelona, Spain.
ORCID: 0000-0001-5665-4685

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Discovery of WLB-89462, a New Drug-like and...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Discovery of WLB-89462, a New Drug-like and...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Peptides bêta-amyloïdes › Discovery of WLB-89462, a New Drug-like and...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Ligands › Discovery of WLB-89462, a New Drug-like and...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Neuroprotection › Discovery of WLB-89462, a New Drug-like and...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents du système nerveux central › Neuroprotecteurs › Discovery of WLB-89462, a New Drug-like and...