Stress Cardiomyopathy Induced by Refractory Hypoglycemia Due to Acute Sulfonylurea Intoxication.

cardiology cardiomyopathy critical care medicine hypoglycemia stress induced cardiomyopathy sulfonylurea sulfonylurea intoxication takotsubo cardiomyopathy

Journal

Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737

Informations de publication

Date de publication:
Jul 2023
Historique:
accepted: 21 07 2023
medline: 23 8 2023
pubmed: 23 8 2023
entrez: 23 8 2023
Statut: epublish

Résumé

Takotsubo cardiomyopathy (TCM) is a reversible syndrome that resembles a myocardial infarction but without typical coronary stenosis and with an apical "ballooning" image present on an echocardiogram. Multiple triggers have been linked to TCM but rarely, acute severe hypoglycemia. This is a case of a 39-year-old woman who was brought to the emergency department after being found unresponsive at home. She was severely hypoglycemic with a glucose of 18 mg/dL and suspected to have sulfonylurea intoxication. The patient was intubated and transferred to our ICU from an outside facility for a higher level of care. The patient was noted to have an elevated troponin and the initial echocardiogram demonstrated TCM. The patient remained persistently hypoglycemic, despite continuous dextrose infusion and glucagon treatment. Stress dose steroids were added with the eventual resolution of hypoglycemia. A repeat echocardiogram demonstrated the resolution of TCM.

Identifiants

pubmed: 37609083
doi: 10.7759/cureus.42279
pmc: PMC10440373
doi:

Types de publication

Case Reports

Langues

eng

Pagination

e42279

Informations de copyright

Copyright © 2023, Shah et al.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Références

Endocr J. 2007 Aug;54(4):631-6
pubmed: 17664847
Yonsei Med J. 2011 Nov;52(6):898-908
pubmed: 22028152
J Cardiol. 1991;21(2):203-14
pubmed: 1841907
Int J Cardiol. 2010 Jul 9;142(2):120-5
pubmed: 20051293
Am J Emerg Med. 2012 Nov;30(9):2098.e1-3
pubmed: 22425000
Int J Cardiol. 2011 Mar 3;147(2):e21-3
pubmed: 19233494
Case Rep Cardiol. 2020 Jun 7;2020:6876951
pubmed: 32566318
Nutrition. 2014 Sep;30(9):1090-2
pubmed: 24927630
Cardiovasc Res. 2004 Jun 1;62(3):558-67
pubmed: 15158148
Intern Med. 2005 Mar;44(3):228-33
pubmed: 15805712

Auteurs

Binoy K Shah (BK)

Internal Medicine, University of Nevada, Reno, Reno, USA.

Nicolas F Fiore (NF)

Internal Medicine, University of Nevada, Reno, Reno, USA.

Fernando J Fuentes (FJ)

Family Medicine, Renown Regional Medical Center, Reno, USA.
Internal Medicine/Pulmonary and Critical Care, University of Nevada, Reno School of Medicine, Reno, USA.
Pulmonology, Renown Health, Reno, USA.

Classifications MeSH