Strong impact of sarcopenic state defined by skeletal muscle mass index on postoperative complication of Crohn's disease patients.
Crohn's disease
Nutritional status
Postoperative complications
Sarcopenia
Skeletal muscle mass index
Journal
Surgery open science
ISSN: 2589-8450
Titre abrégé: Surg Open Sci
Pays: United States
ID NLM: 101768812
Informations de publication
Date de publication:
Sep 2023
Sep 2023
Historique:
received:
01
05
2023
revised:
27
07
2023
accepted:
29
07
2023
medline:
23
8
2023
pubmed:
23
8
2023
entrez:
23
8
2023
Statut:
epublish
Résumé
Malnutrition impacts the clinical course of Crohn's disease; however, there is little evidence of its influence on perioperative adverse events. We assessed whether nutritional indicators are associated with postoperative complications in surgical treatment of Crohn's disease. 137 patients with Crohn's disease who underwent surgical treatment between January 2011 and December 2020 were included. Skeletal muscle index was calculated by a single CT slice. We analyzed the risk factors for adverse events. 37 % of patients had postoperative complications. Adverse events occurred more frequently in patients with high serum C-reactive protein, low serum albumin, prognostic nutritional index <38.3, skeletal muscle index <38.9 cm Skeletal muscle index is the most useful nutritional predictor of postoperative complications in Crohn's disease patients among other nutritional indices. We believe that these patients are at high risk of postoperative complications and need appropriate nutritional support in the perioperative period.
Sections du résumé
Background
UNASSIGNED
Malnutrition impacts the clinical course of Crohn's disease; however, there is little evidence of its influence on perioperative adverse events. We assessed whether nutritional indicators are associated with postoperative complications in surgical treatment of Crohn's disease.
Methods
UNASSIGNED
137 patients with Crohn's disease who underwent surgical treatment between January 2011 and December 2020 were included. Skeletal muscle index was calculated by a single CT slice. We analyzed the risk factors for adverse events.
Results
UNASSIGNED
37 % of patients had postoperative complications. Adverse events occurred more frequently in patients with high serum C-reactive protein, low serum albumin, prognostic nutritional index <38.3, skeletal muscle index <38.9 cm
Conclusions
UNASSIGNED
Skeletal muscle index is the most useful nutritional predictor of postoperative complications in Crohn's disease patients among other nutritional indices. We believe that these patients are at high risk of postoperative complications and need appropriate nutritional support in the perioperative period.
Identifiants
pubmed: 37609367
doi: 10.1016/j.sopen.2023.07.022
pii: S2589-8450(23)00057-X
pmc: PMC10440350
doi:
Types de publication
Journal Article
Langues
eng
Pagination
54-59Informations de copyright
© 2023 The Authors.
Déclaration de conflit d'intérêts
The authors have declared no conflicts of interest.
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