Generation and Characterization of a Humanized Lung Xenograft Mouse Model for Studying Henipavirus Pathogenesis.
BLT reconstitution
Henipavirus
Human lung xenograft
Humanized mouse model
Immune response
NSG mice
Journal
Methods in molecular biology (Clifton, N.J.)
ISSN: 1940-6029
Titre abrégé: Methods Mol Biol
Pays: United States
ID NLM: 9214969
Informations de publication
Date de publication:
2023
2023
Historique:
medline:
24
8
2023
pubmed:
23
8
2023
entrez:
23
8
2023
Statut:
ppublish
Résumé
The development of humanized mouse models has recently opened new avenues in the field of infectious diseases. These models allow research on many human viruses that were once difficult to study, because finding suitable animal models of infection can be challenging, cost prohibitive, and often do not entirely recapitulate all parameters of the disease. Here, we describe the procedure of human immune system reconstitution (humanization) of NOD.Cg-Prkdc
Identifiants
pubmed: 37610583
doi: 10.1007/978-1-0716-3283-3_14
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
191-204Informations de copyright
© 2023. Springer Science+Business Media, LLC, part of Springer Nature.
Références
Agliano A, Martin-Padura I, Mancuso P et al (2008) Human acute leukemia cells injected in NOD/LtSz-scid/IL-2Rgamma null mice generate a faster and more efficient disease compared to other NOD/scid-related strains. Int J Cancer 123:2222–2227
doi: 10.1002/ijc.23772
pubmed: 18688847
Arnold L, Tyagi RK, Meija P et al (2011) Further improvements of the P. falciparum humanized mouse model. PLoS One 6:e18045. 3069031
doi: 10.1371/journal.pone.0018045
pubmed: 21483851
pmcid: 3069031
Foreman O, Kavirayani AM, Griffey SM, Reader R, Shultz LD (2011) Opportunistic bacterial infections in breeding colonies of the NSG mouse strain. Vet Pathol 48:495–499. 3101569
doi: 10.1177/0300985810378282
pubmed: 20817888
Racki WJ, Covassin L, Brehm M et al (2010) NOD-scid IL2rgamma(null) mouse model of human skin transplantation and allograft rejection. Transplantation 89:527–536. 2901915
doi: 10.1097/TP.0b013e3181c90242
pubmed: 20134397
pmcid: 2901915
Sanchez PV, Perry RL, Sarry JE et al (2009) A robust xenotransplantation model for acute myeloid leukemia. Leukemia 23:2109–2117. 3659827
doi: 10.1038/leu.2009.143
pubmed: 19626050
pmcid: 3659827
Zhang L, Meissner E, Chen J, Su L (2010) Current humanized mouse models for studying human immunology and HIV-1 immuno-pathogenesis. Sci China Life Sci 53:195–203. 4224686
doi: 10.1007/s11427-010-0059-7
pubmed: 20596827
pmcid: 4224686
Valbuena G, Halliday H, Borisevich V, Goez Y, Rockx B (2014) A human lung xenograft mouse model of Nipah virus infection. PLoS Pathog 10:e1004063. 3974875
doi: 10.1371/journal.ppat.1004063
pubmed: 24699832
pmcid: 3974875
Berges BK, Rowan MR (2011) The utility of the new generation of humanized mice to study HIV-1 infection: transmission, prevention, pathogenesis, and treatment. Retrovirology 8:65. 3170263
doi: 10.1186/1742-4690-8-65
pubmed: 21835012
pmcid: 3170263
Bird BH, Spengler JR, Chakrabarti AK et al (2016) Humanized mouse model of Ebola virus disease mimics the immune responses in human disease. J Infect Dis 213:703–711. 4747627
doi: 10.1093/infdis/jiv538
pubmed: 26582961
Calderon VE, Valbuena G, Goez Y et al (2013) A humanized mouse model of tuberculosis. PLoS One 8:e63331. 3656943
doi: 10.1371/journal.pone.0063331
pubmed: 23691024
pmcid: 3656943
Lee J, Brehm MA, Greiner D, Shultz LD, Kornfeld H (2013) Engrafted human cells generate adaptive immune responses to Mycobacterium bovis BCG infection in humanized mice. BMC Immunol 14:53. 3924189
doi: 10.1186/1471-2172-14-53
pubmed: 24313934
pmcid: 3924189
Morton JJ, Bird G, Refaeli Y, Jimeno A (2016) Humanized mouse xenograft models: narrowing the tumor-microenvironment gap. Cancer Res 76:6153
doi: 10.1158/0008-5472.CAN-16-1260
pubmed: 27587540
pmcid: 5093075
Nusbaum RJ, Calderon VE, Huante MB et al (2016) Pulmonary tuberculosis in humanized mice infected with HIV-1. Sci Rep 6:21522. 4808832
doi: 10.1038/srep21522
pubmed: 26908312
pmcid: 4808832
Smith DJ, Lin LJ, Moon H et al (2016) Propagating humanized BLT mice for the study of human immunology and immunotherapy. Stem Cells Dev 25:1863
doi: 10.1089/scd.2016.0193
pubmed: 27608727
pmcid: 5165681
Spengler JR, Lavender KJ, Martellaro C et al (2016) Ebola virus replication and disease without immunopathology in mice expressing transgenes to support human myeloid and lymphoid cell engraftment. J Infect Dis 214:S308
doi: 10.1093/infdis/jiw248
pubmed: 27601621
pmcid: 5050473
Stoddart CA, Maidji E, Galkina SA et al (2011) Superior human leukocyte reconstitution and susceptibility to vaginal HIV transmission in humanized NOD-scid IL-2Rgamma(-/-) (NSG) BLT mice. Virology 417:154–160. 3152643
doi: 10.1016/j.virol.2011.05.013
pubmed: 21684569
Escaffre O, Saito TB, Juelich TL et al (2017) Contribution of human lung parenchyma and leukocyte influx to oxidative stress and immune system-mediated pathology following Nipah virus infection. J Virol 91:e00275-17. 5651721
doi: 10.1128/JVI.00275-17
pubmed: 28539439
pmcid: 5651721
Yokoyama WM, Thompson ML, Ehrhardt RO (2012) Cryopreservation and thawing of cells. Curr Protoc Immunol Appendix 3:3G
Cooper PD (1961) The plaque assay of animal viruses. Adv Virus Res 8:319–378
doi: 10.1016/S0065-3527(08)60689-2
pubmed: 13881155
Reed LJMH (1938) A simple method of estimating fifty per cent endpoints. Am J Hyg 27:493–497
Chomczynski P, Sacchi N (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156–159
doi: 10.1016/0003-2697(87)90021-2
pubmed: 2440339
Chomczynski P, Sacchi N (2006) The single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction: twenty-something years on. Nat Protoc 1:581–585
doi: 10.1038/nprot.2006.83
pubmed: 17406285
Boom R, Sol CJ, Salimans MM, Jansen CL, Wertheim-van Dillen PM, van der Noordaa J (1990) Rapid and simple method for purification of nucleic acids. J Clin Microbiol 28:495–503. 269651
doi: 10.1128/jcm.28.3.495-503.1990
pubmed: 1691208
pmcid: 269651