Biomechanics, Energetics, and Structural Basis of Rupture of Fibrin Networks.

energetics of ruptures fluctuating spring model rupture of fibrin clots stress-strain curves

Journal

Advanced healthcare materials
ISSN: 2192-2659
Titre abrégé: Adv Healthc Mater
Pays: Germany
ID NLM: 101581613

Informations de publication

Date de publication:
10 2023
Historique:
revised: 06 08 2023
received: 16 02 2023
medline: 30 10 2023
pubmed: 23 8 2023
entrez: 23 8 2023
Statut: ppublish

Résumé

Fibrin provides the main structural integrity and mechanical strength to blood clots. Failure of fibrin clots can result in life-threating complications, such as stroke or pulmonary embolism. The dependence of rupture resistance of fibrin networks (uncracked and cracked) on fibrin(ogen) concentrations in the (patho)physiological 1-5 g L

Identifiants

pubmed: 37611209
doi: 10.1002/adhm.202300096
doi:

Substances chimiques

Fibrin 9001-31-4
Hemostatics 0
Fibrinogen 9001-32-5

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2300096

Subventions

Organisme : NHLBI NIH HHS
ID : R01 HL148227
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL135254
Pays : United States
Organisme : NHLBI NIH HHS
ID : R00 HL148646
Pays : United States
Organisme : NIH HHS
ID : S10 OD018041
Pays : United States

Informations de copyright

© 2023 The Authors. Advanced Healthcare Materials published by Wiley-VCH GmbH.

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Auteurs

Ranjini K Ramanujam (RK)

Department of Biomedical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ, 08854, USA.

Farkhad Maksudov (F)

Department of Chemistry, University of Massachusetts, Lowell, MA, 01854, USA.

Rustem I Litvinov (RI)

Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.

Chandrasekaran Nagaswami (C)

Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.

John W Weisel (JW)

Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.

Valerie Tutwiler (V)

Department of Biomedical Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ, 08854, USA.

Valeri Barsegov (V)

Department of Chemistry, University of Massachusetts, Lowell, MA, 01854, USA.

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