Rare complication of doxorubicin-induced complete heart block in a patient with Hodgkin's lymphoma: a case report.
Antineoplastic agents
Case Reports
DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS
Heart failure
MEDICAL ONCOLOGY
Journal
European journal of hospital pharmacy : science and practice
ISSN: 2047-9956
Titre abrégé: Eur J Hosp Pharm
Pays: England
ID NLM: 101578294
Informations de publication
Date de publication:
09 2023
09 2023
Historique:
received:
09
06
2022
accepted:
16
08
2022
pmc-release:
01
09
2024
medline:
25
8
2023
pubmed:
24
8
2023
entrez:
23
8
2023
Statut:
ppublish
Résumé
Anthracyclines are associated with cardiotoxic manifestations that are mainly dose-dependent, with onset varying from a few days to many years after stopping treatment. Frequent monitoring for toxic manifestations, early detection, cessation of anthracycline use and appropriate treatment is the key to preventing morbidity and mortality. Complete heart block with doxorubicin use in Hodgkin's lymphoma is rarely reported, and is a severe toxic manifestation necessitating withdrawal or changing of regimen to etoposide + bleomycin + vinblastine + dacarbazine (EBVD), as in this case.
Identifiants
pubmed: 37611964
pii: ejhpharm-2022-003417
doi: 10.1136/ejhpharm-2022-003417
pmc: PMC10447958
doi:
Substances chimiques
Doxorubicin
80168379AG
Anthracyclines
0
Dacarbazine
7GR28W0FJI
Polyketides
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e26Informations de copyright
© European Association of Hospital Pharmacists 2023. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
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