The Impact of Vitamin D Supplementation on Improving Blood Pressure: Evidence Obtained From an Umbrella Meta-analysis.
Blood pressure
Cholecalciferol
Umbrella meta-analysis
Vitamin D
Journal
Clinical therapeutics
ISSN: 1879-114X
Titre abrégé: Clin Ther
Pays: United States
ID NLM: 7706726
Informations de publication
Date de publication:
10 2023
10 2023
Historique:
received:
21
04
2023
revised:
07
07
2023
accepted:
25
07
2023
medline:
13
11
2023
pubmed:
24
8
2023
entrez:
23
8
2023
Statut:
ppublish
Résumé
The results of meta-analyses regarding the effect of vitamin D on blood pressure are conflicting. The present umbrella meta-analysis was conducted to provide definite and conclusive results. Systematically, Scopus, EMBASE, PubMed, and Web of Science databases and Google Scholar were searched for relevant literature published up to July 2022. All meta-analyses of clinical trials addressing the effect of vitamin D on blood pressure were included. Random effects analysis was performed to obtain the overall effect size based on the standardized mean differences (SMDs) and weighted mean differences (WMDs) separately. The quality of included meta-analyses was assessed by using the Measurement Tool for Assessing Multiple Systematic Reviews 2 questionnaire. Overall, 21 meta-analyses were enrolled in the umbrella review. The results indicated that systolic blood pressure was significantly reduced after the intervention based on WMD effect size analysis (ES Based on obtained evidence, vitamin D could be considered an efficient adjuvant for improving blood pressure.
Identifiants
pubmed: 37612170
pii: S0149-2918(23)00294-1
doi: 10.1016/j.clinthera.2023.07.020
pii:
doi:
Substances chimiques
Vitamin D
1406-16-2
Vitamins
0
Types de publication
Meta-Analysis
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
e208-e216Informations de copyright
Copyright © 2023 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest None declared.