Sesame allergy in children: New insights into diagnosis and management.

Ses i 1 component-resolved diagnostics cosensitization oral food challenge peanut allergy sesame allergy skin prick testing

Journal

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology
ISSN: 1399-3038
Titre abrégé: Pediatr Allergy Immunol
Pays: England
ID NLM: 9106718

Informations de publication

Date de publication:
08 2023
Historique:
revised: 30 06 2023
received: 10 01 2023
accepted: 07 07 2023
medline: 28 8 2023
pubmed: 25 8 2023
entrez: 25 8 2023
Statut: ppublish

Résumé

Sesame is a potentially potent allergen that can trigger skin, gastrointestinal, and respiratory tract symptoms, and anaphylaxis. Only 20% to 30% of sesame-allergic children develop tolerance. The prevalence of sesame allergy depends on local diets and ranges from 0.1% to 0.9%. A high risk of accidental exposure to sesame has resulted in mandatory food labeling in many countries. More than half of patients with sesame allergy are also allergic to peanut/tree nuts. Serum-specific IgE testing with a quantitative Ses i 1 component can be performed safely and has higher clinical specificity and better positive predictive value for oral food challenge (OFC) than whole sesame extract or skin prick testing (SPT). Compared with SPT or OFC, in vitro Ses i 1 testing requires no special techniques and carries no risk of reactions. Diagnosis of suspected sesame allergy begins with a thorough history and physical examination. A positive sesame extract test (≥0.1 kU

Identifiants

pubmed: 37622261
doi: 10.1111/pai.14001
doi:

Substances chimiques

Plant Extracts 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e14001

Informations de copyright

© 2023 The Authors. Pediatric Allergy and Immunology published by European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd.

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Auteurs

Sarah Saf (S)

Allergology Department, Hopital A. Trousseau, Sorbonne Universite, Paris, France.

Magnus P Borres (MP)

Thermo Fisher Scientific, Phadia AB, Uppsala, Sweden.
Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.

Eva Södergren (E)

Thermo Fisher Scientific, Phadia AB, Uppsala, Sweden.

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