Major Adverse Cardiac and Cerebrovascular Events in Patients Undergoing Simultaneous Heart Surgery and Carotid Endarterectomy.

CABG carotid TEA carotid endarterectomy open heart surgery valve surgery

Journal

Journal of cardiovascular development and disease
ISSN: 2308-3425
Titre abrégé: J Cardiovasc Dev Dis
Pays: Switzerland
ID NLM: 101651414

Informations de publication

Date de publication:
02 Aug 2023
Historique:
received: 18 05 2023
revised: 13 07 2023
accepted: 01 08 2023
medline: 25 8 2023
pubmed: 25 8 2023
entrez: 25 8 2023
Statut: epublish

Résumé

Patients with simultaneous relevant internal carotid artery stenosis and coronary artery heart or valve disease represent a high-risk collective with respect to cerebral or cardiovascular severe events when undergoing surgery. There exist several concepts regarding the timing and modality of carotid revascularization, which are controversially discussed in patients with heart disease. More data regarding outcome predictors and measures are needed to gain a better understanding of the best treatment option of the discussed patient collective. This single-center study retrospectively analyzed Preoperative patient's characteristic in the no-MACCE and MACCE group were mainly balanced, other than higher rates of chronic obstructive pulmonary disease, chronic kidney disease, instable angina pectoris and prior transitory ischemic attack in the MACCE cohort. The analysis of intraoperative characteristics revealed a higher number of intra-aortic balloon pump implantation, which is in line for a higher number of postoperative supports. Besides MACCE, patients suffered significantly more often from postoperative bleeding events and re-thoracotomy, cardiopulmonary reanimation, new onset postoperative dialysis and prolonged intensive care unit stay related complications. Within the reported patient population suffering from MACCE after a simultaneous carotid endarterectomy and heart surgery, a preoperative history of transitory ischemic attack and kidney disease might account for worse outcomes, as severe events were not only neurologically driven but also associated with postoperative cardiovascular complications following heart surgical procedures.

Sections du résumé

BACKGROUND BACKGROUND
Patients with simultaneous relevant internal carotid artery stenosis and coronary artery heart or valve disease represent a high-risk collective with respect to cerebral or cardiovascular severe events when undergoing surgery. There exist several concepts regarding the timing and modality of carotid revascularization, which are controversially discussed in patients with heart disease. More data regarding outcome predictors and measures are needed to gain a better understanding of the best treatment option of the discussed patient collective.
METHODS METHODS
This single-center study retrospectively analyzed
RESULTS RESULTS
Preoperative patient's characteristic in the no-MACCE and MACCE group were mainly balanced, other than higher rates of chronic obstructive pulmonary disease, chronic kidney disease, instable angina pectoris and prior transitory ischemic attack in the MACCE cohort. The analysis of intraoperative characteristics revealed a higher number of intra-aortic balloon pump implantation, which is in line for a higher number of postoperative supports. Besides MACCE, patients suffered significantly more often from postoperative bleeding events and re-thoracotomy, cardiopulmonary reanimation, new onset postoperative dialysis and prolonged intensive care unit stay related complications.
CONCLUSIONS CONCLUSIONS
Within the reported patient population suffering from MACCE after a simultaneous carotid endarterectomy and heart surgery, a preoperative history of transitory ischemic attack and kidney disease might account for worse outcomes, as severe events were not only neurologically driven but also associated with postoperative cardiovascular complications following heart surgical procedures.

Identifiants

pubmed: 37623343
pii: jcdd10080330
doi: 10.3390/jcdd10080330
pmc: PMC10455249
pii:
doi:

Types de publication

Journal Article

Langues

eng

Références

J Am Coll Cardiol. 2011 Feb 15;57(7):779-83
pubmed: 21310312
N Engl J Med. 2007 Feb 15;356(7):706-13
pubmed: 17301301
Ann Vasc Surg. 2007 Jul;21(4):408-14
pubmed: 17502133
J Card Surg. 2022 Dec;37(12):4692-4697
pubmed: 36349716
Stroke. 2017 Oct;48(10):2769-2775
pubmed: 28916664
Interact Cardiovasc Thorac Surg. 2006 Apr;5(2):159-65
pubmed: 17670540
Vasc Endovascular Surg. 2022 Aug;56(6):566-570
pubmed: 35499500
N Engl J Med. 1996 Dec 19;335(25):1857-63
pubmed: 8948560
Interact Cardiovasc Thorac Surg. 2012 Dec;15(6):984-8
pubmed: 22968959
J Vasc Surg. 2021 Feb;73(2):542-547
pubmed: 32682062
J Thorac Cardiovasc Surg. 2018 Oct;156(4):1451-1457.e4
pubmed: 29754790
Ann Vasc Surg. 2020 Jan;62:463-473.e4
pubmed: 31449948
Eur J Vasc Endovasc Surg. 2017 Mar;53(3):309-319
pubmed: 28094166
Atherosclerosis. 2013 Apr;227(2):193-200
pubmed: 23218802
Eur Heart J. 2018 Mar 1;39(9):763-816
pubmed: 28886620
Eur J Vasc Endovasc Surg. 2011 May;41(5):607-24
pubmed: 21396854
J Vasc Surg. 2023 May;77(5):1424-1433.e1
pubmed: 36681256
Eur J Vasc Endovasc Surg. 2002 Apr;23(4):283-94
pubmed: 11991687
J Vasc Surg. 2019 Sep;70(3):815-823
pubmed: 30850293
Eur J Vasc Endovasc Surg. 2003 May;25(5):380-9
pubmed: 12713775
Eur Heart J. 2019 Jan 7;40(2):87-165
pubmed: 30165437
J Vasc Surg. 2005 Mar;41(3):397-401; discussion 401-2
pubmed: 15838469
Vascular. 2020 Dec;28(6):808-815
pubmed: 32493182
JACC Cardiovasc Interv. 2017 Feb 13;10(3):286-298
pubmed: 28183469
J Thorac Cardiovasc Surg. 2007 Sep;134(3):690-6
pubmed: 17723819
Perfusion. 2022 Jul 15;:2676591221114953
pubmed: 35841145
J Vasc Surg. 2006 Jul;44(1):67-72
pubmed: 16828428
Ann Thorac Surg. 2000 Feb;69(2):421-4
pubmed: 10735674
Int J Cardiol. 2018 Mar 1;254:36-42
pubmed: 29407124
Cardiovasc Surg. 2000 Jan;8(1):31-40
pubmed: 10661701
J Vasc Surg. 2020 Aug;72(2):589-596.e3
pubmed: 32067876

Auteurs

Stephen Gerfer (S)

Department of Cardiothoracic Surgery, Heart Center, University Hospital of Cologne, 50937 Cologne, Germany.

Walid Bennour (W)

Department of Cardiothoracic Surgery, Heart Center, University Hospital of Cologne, 50937 Cologne, Germany.

Alina Chigri (A)

Department of Cardiothoracic Surgery, Heart Center, University Hospital of Cologne, 50937 Cologne, Germany.

Ahmed Elderia (A)

Department of Cardiothoracic Surgery, Heart Center, University Hospital of Cologne, 50937 Cologne, Germany.

Ihor Krasivskyi (I)

Department of Cardiothoracic Surgery, Heart Center, University Hospital of Cologne, 50937 Cologne, Germany.

Clara Großmann (C)

Department of Cardiothoracic Surgery, Heart Center, University Hospital of Cologne, 50937 Cologne, Germany.

Christopher Gaisendrees (C)

Department of Cardiothoracic Surgery, Heart Center, University Hospital of Cologne, 50937 Cologne, Germany.

Borko Ivanov (B)

Department of Cardiothoracic Surgery, Heart Center, University Hospital of Cologne, 50937 Cologne, Germany.

Soi Avgeridou (S)

Department of Cardiothoracic Surgery, Heart Center, University Hospital of Cologne, 50937 Cologne, Germany.

Kaveh Eghbalzadeh (K)

Department of Cardiothoracic Surgery, Heart Center, University Hospital of Cologne, 50937 Cologne, Germany.

Parwis Rahmanian (P)

Department of Cardiothoracic Surgery, Heart Center, University Hospital of Cologne, 50937 Cologne, Germany.

Ferdinand Kuhn-Régnier (F)

Department of Cardiothoracic Surgery, Heart Center, University Hospital of Cologne, 50937 Cologne, Germany.

Navid Mader (N)

Department of Cardiothoracic Surgery, Heart Center, University Hospital of Cologne, 50937 Cologne, Germany.

Ilija Djordjevic (I)

Department of Cardiothoracic Surgery, Heart Center, University Hospital of Cologne, 50937 Cologne, Germany.

Anton Sabashnikov (A)

Department of Cardiothoracic Surgery, Heart Center, University Hospital of Cologne, 50937 Cologne, Germany.

Thorsten Wahlers (T)

Department of Cardiothoracic Surgery, Heart Center, University Hospital of Cologne, 50937 Cologne, Germany.

Classifications MeSH