Potential Use of Vivascope for Real-Time Histological Evaluation in Endoscopic Laryngeal Surgery.
artificial intelligence
confocal laser scanning microscopy
endoscopic laryngeal surgery
laryngeal dysplasia
Journal
Journal of personalized medicine
ISSN: 2075-4426
Titre abrégé: J Pers Med
Pays: Switzerland
ID NLM: 101602269
Informations de publication
Date de publication:
12 Aug 2023
12 Aug 2023
Historique:
received:
07
07
2023
revised:
02
08
2023
accepted:
10
08
2023
medline:
25
8
2023
pubmed:
25
8
2023
entrez:
25
8
2023
Statut:
epublish
Résumé
We aimed to assess the feasibility of using confocal laser scanning microscopy (CLSM) for the real-time ex vivo examination of histological samples of laryngeal lesions and to evaluate the correlation between CLSM and definitive histological results. This preliminary study included eight consecutive patients with "suspected" laryngeal lesions who were candidates for endoscopic laryngeal surgery. The obtained samples were evaluated using CLSM and classified as "inadequate" or "adequate" (high- and low-grade dysplasia, in situ and invasive carcinoma, positive surgical margin, and inflammatory outbreaks). CLSM showed the macro image in all cases and generated a digital version. All the samples were defined as adequate during CLSM and confirmed at histopathology: low-grade dysplasia (
Identifiants
pubmed: 37623502
pii: jpm13081252
doi: 10.3390/jpm13081252
pmc: PMC10455566
pii:
doi:
Types de publication
Journal Article
Langues
eng
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