Characteristics and Quality Appraisal of the Economic Evaluations Done in Ethiopia: A Systematic Review.


Journal

PharmacoEconomics - open
ISSN: 2509-4254
Titre abrégé: Pharmacoecon Open
Pays: Switzerland
ID NLM: 101700780

Informations de publication

Date de publication:
Nov 2023
Historique:
accepted: 23 07 2023
medline: 25 8 2023
pubmed: 25 8 2023
entrez: 25 8 2023
Statut: ppublish

Résumé

Health economic evaluation identifies, measures, values, and compares alternative strategies to efficiently allocate scarce resources. The validity, methodological quality, and generalizability of economic evaluations must be assessed, as poorly designed studies can lead to incorrect conclusions. Therefore, this study aimed to evaluate the quality and characteristics of published economic evaluations done in Ethiopia, using the Quality of Health Economics Studies (QHES) and Consolidated Health Economic Evaluation Reporting Standards (CHEERS) instruments. Various electronic databases were searched using different keywords. We included only original studies conducted in Ethiopia that evaluated the cost and consequences of at least two health interventions. Abstracts, treatment guidelines, reviews, expert opinions, and studies that included other countries were excluded. Two reviewers independently evaluated each study using the QHES and CHEERS instruments and any disagreements were then resolved by a third reviewer. The study included 21 studies published between 2002 and 2021. HIV was the most frequently evaluated medical condition, examined in four (19.06%) of the 21 studies. Seventeen of the studies (80.95%) compared healthcare services or programs, while the other four examined pharmaceutical products. Cost-utility analysis was the economic evaluation technique used in 14 studies (66.67%). Of the studies that disclosed their funding sources, foreign institutions were involved in funding 71.43% of them. Disability-adjusted life-year (DALY) was an outcome metric used in nine (42.86%) studies. The average QHES score of the studies was 82%. Fourteen studies had QHES scores of ≥75% and two had scores of <50%. The studies evaluated using the CHEERS instrument ranged in quality from 42.9% to 92.9%, with an average of 78.23%. Our study revealed that Ethiopia lacks health economic evaluations, particularly on non-communicable diseases. This indicates that the economic evaluation of healthcare interventions in Ethiopia is still in its early stages. Additionally, Ethiopian institutions have played a very limited role in funding research, highlighting the importance of active participation from local institutions.

Sections du résumé

BACKGROUND BACKGROUND
Health economic evaluation identifies, measures, values, and compares alternative strategies to efficiently allocate scarce resources. The validity, methodological quality, and generalizability of economic evaluations must be assessed, as poorly designed studies can lead to incorrect conclusions. Therefore, this study aimed to evaluate the quality and characteristics of published economic evaluations done in Ethiopia, using the Quality of Health Economics Studies (QHES) and Consolidated Health Economic Evaluation Reporting Standards (CHEERS) instruments.
METHODOLOGY METHODS
Various electronic databases were searched using different keywords. We included only original studies conducted in Ethiopia that evaluated the cost and consequences of at least two health interventions. Abstracts, treatment guidelines, reviews, expert opinions, and studies that included other countries were excluded. Two reviewers independently evaluated each study using the QHES and CHEERS instruments and any disagreements were then resolved by a third reviewer.
RESULT RESULTS
The study included 21 studies published between 2002 and 2021. HIV was the most frequently evaluated medical condition, examined in four (19.06%) of the 21 studies. Seventeen of the studies (80.95%) compared healthcare services or programs, while the other four examined pharmaceutical products. Cost-utility analysis was the economic evaluation technique used in 14 studies (66.67%). Of the studies that disclosed their funding sources, foreign institutions were involved in funding 71.43% of them. Disability-adjusted life-year (DALY) was an outcome metric used in nine (42.86%) studies. The average QHES score of the studies was 82%. Fourteen studies had QHES scores of ≥75% and two had scores of <50%. The studies evaluated using the CHEERS instrument ranged in quality from 42.9% to 92.9%, with an average of 78.23%.
CONCLUSION CONCLUSIONS
Our study revealed that Ethiopia lacks health economic evaluations, particularly on non-communicable diseases. This indicates that the economic evaluation of healthcare interventions in Ethiopia is still in its early stages. Additionally, Ethiopian institutions have played a very limited role in funding research, highlighting the importance of active participation from local institutions.

Identifiants

pubmed: 37624553
doi: 10.1007/s41669-023-00433-y
pii: 10.1007/s41669-023-00433-y
doi:

Types de publication

Systematic Review

Langues

eng

Pagination

877-886

Informations de copyright

© 2023. The Author(s).

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Auteurs

Bereket Bahiru Tefera (BB)

Bahir Dar University College of Medicine and Health Sciences, Bahir Dar, Ethiopia. brktbahiru@gmail.com.

Desalegn Getnet Demsie (DG)

Bahir Dar University College of Medicine and Health Sciences, Bahir Dar, Ethiopia.

Adane Yehualaw (A)

Bahir Dar University College of Medicine and Health Sciences, Bahir Dar, Ethiopia.

Chernet Tafere (C)

Bahir Dar University College of Medicine and Health Sciences, Bahir Dar, Ethiopia.

Kebede Feyisa (K)

Bahir Dar University College of Medicine and Health Sciences, Bahir Dar, Ethiopia.

Malede Berihun Yismaw (MB)

Bahir Dar University College of Medicine and Health Sciences, Bahir Dar, Ethiopia.

Belayneh Kefale (B)

Bahir Dar University College of Medicine and Health Sciences, Bahir Dar, Ethiopia.

Zewdu Yilma (Z)

Bahir Dar University College of Medicine and Health Sciences, Bahir Dar, Ethiopia.

Classifications MeSH