Alginate templated synthesis, characterization and in vitro osteogenic evaluation of strontium-substituted hydroxyapatite.

Alginate Bone regeneration Crystallization Hydroxyapatite Strontium

Journal

International journal of biological macromolecules
ISSN: 1879-0003
Titre abrégé: Int J Biol Macromol
Pays: Netherlands
ID NLM: 7909578

Informations de publication

Date de publication:
01 Dec 2023
Historique:
received: 09 05 2023
revised: 17 08 2023
accepted: 22 08 2023
medline: 15 11 2023
pubmed: 26 8 2023
entrez: 25 8 2023
Statut: ppublish

Résumé

The objective of this study is to explore the potential role of alginate (Alg) in the crystallization of metal-substituted hydroxyapatite, with application in orthopaedic reconstruction. The alginate at different concentrations (0.5 and 1.0 wt%) facilitated in situ mineralization of hydroxyapatite (HA) and strontium-substituted HA (SHA, 10 and 30 mol%). The incorporation of the biopolymer and dopant induced notable changes in HA, including reduced crystal size from 31.0 to 16.4 nm and increased lattice volume from 577.3 to 598.0 Å

Identifiants

pubmed: 37625758
pii: S0141-8130(23)03374-3
doi: 10.1016/j.ijbiomac.2023.126478
pii:
doi:

Substances chimiques

strontium hydroxyapatite 0
Hydroxyapatites 0
Durapatite 91D9GV0Z28
Strontium YZS2RPE8LE
Alginates 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

126478

Informations de copyright

Copyright © 2023 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

C R Akshata (CR)

Department of Polymer Science, University of Madras, Guindy Campus, Chennai 600025, Tamil Nadu, India. Electronic address: akshata.bang@gmail.com.

E Murugan (E)

Department of Physical Chemistry, University of Madras, Guindy Campus, Chennai 600025, Tamil Nadu, India.

G Harichandran (G)

Department of Polymer Science, University of Madras, Guindy Campus, Chennai 600025, Tamil Nadu, India. Electronic address: umhari@unom.ac.in.

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Classifications MeSH