Alginate templated synthesis, characterization and in vitro osteogenic evaluation of strontium-substituted hydroxyapatite.
Alginate
Bone regeneration
Crystallization
Hydroxyapatite
Strontium
Journal
International journal of biological macromolecules
ISSN: 1879-0003
Titre abrégé: Int J Biol Macromol
Pays: Netherlands
ID NLM: 7909578
Informations de publication
Date de publication:
01 Dec 2023
01 Dec 2023
Historique:
received:
09
05
2023
revised:
17
08
2023
accepted:
22
08
2023
medline:
15
11
2023
pubmed:
26
8
2023
entrez:
25
8
2023
Statut:
ppublish
Résumé
The objective of this study is to explore the potential role of alginate (Alg) in the crystallization of metal-substituted hydroxyapatite, with application in orthopaedic reconstruction. The alginate at different concentrations (0.5 and 1.0 wt%) facilitated in situ mineralization of hydroxyapatite (HA) and strontium-substituted HA (SHA, 10 and 30 mol%). The incorporation of the biopolymer and dopant induced notable changes in HA, including reduced crystal size from 31.0 to 16.4 nm and increased lattice volume from 577.3 to 598.0 Å
Identifiants
pubmed: 37625758
pii: S0141-8130(23)03374-3
doi: 10.1016/j.ijbiomac.2023.126478
pii:
doi:
Substances chimiques
strontium hydroxyapatite
0
Hydroxyapatites
0
Durapatite
91D9GV0Z28
Strontium
YZS2RPE8LE
Alginates
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
126478Informations de copyright
Copyright © 2023 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.