Intake of the Total, Classes, and Subclasses of (Poly)Phenols and Risk of Prostate Cancer: A Prospective Analysis of the EPIC Study.

EPIC cohort diet intake polyphenols prostate cancer

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
11 Aug 2023
Historique:
received: 26 06 2023
revised: 08 08 2023
accepted: 10 08 2023
medline: 26 8 2023
pubmed: 26 8 2023
entrez: 26 8 2023
Statut: epublish

Résumé

Existing epidemiological evidence regarding the potential role of (poly)phenol intake in prostate cancer (PCa) risk is scarce and, in the case of flavonoids, it has been suggested that their intake may increase PCa risk. We investigated the associations between the intake of the total and individual classes and subclasses of (poly)phenols and the risk of PCa, including clinically relevant subtypes. The European Prospective Investigation into Cancer and Nutrition (EPIC) cohort included 131,425 adult men from seven European countries. (Poly)phenol intake at baseline was assessed by combining validated center/country-specific dietary questionnaires and the Phenol-Explorer database. Multivariable-adjusted Cox proportional hazards models were used to estimate the hazard ratios (HR) and 95% confidence intervals (CI). In total, 6939 incident PCa cases (including 3501 low-grade and 710 high-grade, 2446 localized and 1268 advanced, and 914 fatal Pca cases) were identified during a mean follow-up of 14 years. No associations were observed between the total intake of (poly)phenols and the risk of PCa, either overall (HR

Identifiants

pubmed: 37627095
pii: cancers15164067
doi: 10.3390/cancers15164067
pmc: PMC10452452
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : La Marató de TV-3
ID : 553/C/2019
Organisme : Instituto de Salud Carlos III
ID : PI18/0191
Organisme : Instituto de Salud Carlos III
ID : PI22/0412
Organisme : Instituto de Salud Carlos III
ID : CB16/10/00269
Organisme : Agency for Administration of University and Research
ID : 2021SGR00687
Organisme : Ministerio de Ciencia e Innovación España
ID : CEX2021-001234-M
Organisme : Ministerio de Ciencia e Innovación España
ID : PID2020-114921RB-C21
Organisme : Instituto de Salud Carlos III
ID : CD20/00071
Organisme : Instituto de Salud Carlos III
ID : CPII20/00009
Organisme : Agency for Administration of University and Research
ID : 2021SGR00481

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Auteurs

Enrique Almanza-Aguilera (E)

Unit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), 08908 Barcelona, Spain.

Daniel Guiñón-Fort (D)

Unit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), 08908 Barcelona, Spain.

Aurora Perez-Cornago (A)

Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.

Miriam Martínez-Huélamo (M)

Biomarkers and Nutrimetabolomics Laboratory, Department of Nutrition, Food Sciences and Gastronomy, Nutrition and Food Safety Research Institute (INSA), Food Innovation Network (XIA), Faculty of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain.
Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, 28029 Madrid, Spain.

Cristina Andrés-Lacueva (C)

Biomarkers and Nutrimetabolomics Laboratory, Department of Nutrition, Food Sciences and Gastronomy, Nutrition and Food Safety Research Institute (INSA), Food Innovation Network (XIA), Faculty of Pharmacy and Food Sciences, University of Barcelona, 08028 Barcelona, Spain.
Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (CIBERFES), Instituto de Salud Carlos III, 28029 Madrid, Spain.

Anne Tjønneland (A)

Danish Cancer Society Research Center, Danish Cancer Society, 2100 Copenhagen, Denmark.
Department of Public Health, University of Copenhagen, 2177 Copenhagen, Denmark.

Anne Kirstine Eriksen (AK)

Danish Cancer Society Research Center, Danish Cancer Society, 2100 Copenhagen, Denmark.

Verena Katzke (V)

Department of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.

Rashmita Bajracharya (R)

Department of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.

Matthias B Schulze (MB)

Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, 14558 Nuthetal, Germany.
Institute of Nutritional Science, University of Potsdam, 14558 Nuthetal, Germany.

Giovanna Masala (G)

Cancer Risk Factors and Life-Style Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network-ISPRO, 50139 Florence, Italy.

Andreina Oliverio (A)

Epidemiology and Prevention Unit, Department of Epidemiology and Data Science, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, 20133 Milan, Italy.

Rosario Tumino (R)

Hyblean Association for Epidemiological Research (AIRE-ONLUS), 97100 Ragusa, Italy.

Luca Manfredi (L)

Department of Clinical and Biological Sciences, University of Turin, 10043 Orbassano, Italy.

Cristina Lasheras (C)

Functional Biology Department, University of Oviedo, 33003 Oviedo, Spain.

Marta Crous-Bou (M)

Unit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), 08908 Barcelona, Spain.

Maria-José Sánchez (MJ)

Granada Cancer Registry, Andalusian School of Public Health (EASP), Instituto de Investigación Biosanitaria Ibs. GRANADA, University of Granada, 18011 Granada, Spain.
Instituto de Investigación Biosanitaria Ibs. GRANADA, 18012 Granada, Spain.
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), 28029 Madrid, Spain.
Department of Preventive Medicine and Public Health, University of Granada, 18071 Granada, Spain.

Pilar Amiano (P)

Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), 28029 Madrid, Spain.
Ministry of Health of the Basque Government, Sub Directorate for Public Health and Addictions of Gipuzkoa, 20013 San Sebastian, Spain.
Epidemiology of Chronic and Communicable Diseases Group, BioGipuzkoa Health Research Institute, 20014 San Sebastian, Spain.

Sandra M Colorado-Yohar (SM)

Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), 28029 Madrid, Spain.
Department of Epidemiology, Murcia Regional Health Council, IMIB-Arrixaca, Murcia University, 30003 Murcia, Spain.
Research Group on Demography and Health, National Faculty of Public Health, University of Antioquia, Medellín 050010, Colombia.

Marcela Guevara (M)

Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), 28029 Madrid, Spain.
Navarra Public Health Institute, 31003 Pamplona, Spain.
Navarra Institute for Health Research (IdiSNA), 31008 Pamplona, Spain.

Emily Sonestedt (E)

Nutritional Epidemiology, Department of Clinical Sciences Malmö, Lund University, 214 28 Malmö, Sweden.

Anders Bjartell (A)

Department of Urology, Skåne University Hospital, 205 02 Malmö, Sweden.

Elin Thysell (E)

Department of Medical Biosciences, Umeå University, 901 87 Umeå, Sweden.

Elisabete Weiderpass (E)

International Agency for Research on Cancer (IARC/WHO), 69372 Lyon, France.

Dagfinn Aune (D)

Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London W2 1PG, UK.
Department of Nutrition, Oslo New University College, 0456 Oslo, Norway.
Department of Endocrinology, Morbid Obesity and Preventive Medicine, Oslo University Hospital, 0424 Oslo, Norway.

Elom K Aglago (EK)

Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London W2 1PG, UK.

Ruth C Travis (RC)

Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.

Raul Zamora-Ros (R)

Unit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), 08908 Barcelona, Spain.

Classifications MeSH