The Dual Role of Necroptosis in Pancreatic Ductal Adenocarcinoma.
cell death
necroptosis
pancreatic cancer
tumor microenvironment
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
10 Aug 2023
10 Aug 2023
Historique:
received:
09
07
2023
revised:
05
08
2023
accepted:
08
08
2023
medline:
28
8
2023
pubmed:
26
8
2023
entrez:
26
8
2023
Statut:
epublish
Résumé
Pancreatic cancer (PC) is the seventh leading cause of cancer-related death. PC incidence has continued to increase by about 1% each year in both men and women. Although the 5-year relative survival rate of PC has increased from 3% to 12%, it is still the lowest among cancers. Hence, novel therapeutic strategies are urgently needed. Challenges in PC-targeted therapeutic strategies stem from the high PC heterogeneity and from the poorly understood interplay between cancer cells and the surrounding microenvironment. Signaling pathways that drive PC cell growth have been the subject of intense scrutiny and interest has been attracted by necroptosis, a distinct type of programmed cell death. In this review, we provide a historical background on necroptosis and a detailed analysis of the ongoing debate on the role of necroptosis in PC malignant progression.
Identifiants
pubmed: 37628814
pii: ijms241612633
doi: 10.3390/ijms241612633
pmc: PMC10454309
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Références
Radiology. 2018 May;287(2):374-390
pubmed: 29668413
PLoS One. 2020 Jan 30;15(1):e0228015
pubmed: 31999765
Biomolecules. 2022 Jun 13;12(6):
pubmed: 35740953
World J Gastrointest Surg. 2020 Dec 27;12(12):468-490
pubmed: 33437400
JAMA. 2021 Sep 7;326(9):851-862
pubmed: 34547082
Histopathology. 2020 Jan;76(2):182-188
pubmed: 31433515
Carcinogenesis. 2016 May;37(5):522-9
pubmed: 26992898
J Pathol. 2018 Dec;246(4):395-404
pubmed: 30105857
World J Gastroenterol. 2014 Aug 21;20(31):10778-89
pubmed: 25152581
Front Physiol. 2013 Nov 01;4:318
pubmed: 24198790
Ann Surg. 2013 Aug;258(2):324-30
pubmed: 23532107
Hum Pathol. 2006 Nov;37(11):1498-502
pubmed: 16996571
J Pathol. 2017 Oct;243(2):148-154
pubmed: 28722124
Cell Res. 2018 Aug;28(8):868-870
pubmed: 29941926
Mol Cancer. 2003 Jan 07;2:6
pubmed: 12605713
Mod Pathol. 2019 Dec;32(12):1806-1813
pubmed: 31285527
Semin Diagn Pathol. 2000 Feb;17(1):31-42
pubmed: 10721805
Sci Rep. 2011;1:161
pubmed: 22355676
Cell. 2021 Dec 9;184(25):6081-6100.e26
pubmed: 34861191
J Hepatobiliary Pancreat Surg. 2007;14(3):224-32
pubmed: 17520196
Ann Oncol. 2010 May;21 Suppl 5:v55-8
pubmed: 20555103
Int J Mol Sci. 2021 Dec 30;23(1):
pubmed: 35008832
Int J Radiat Oncol Biol Phys. 2003 Sep 1;57(1):90-7
pubmed: 12909220
Sci Transl Med. 2011 Aug 10;3(95):95ra73
pubmed: 21832238
Front Physiol. 2022 Mar 04;13:856803
pubmed: 35309060
Pancreas. 2020 Aug;49(7):999-1003
pubmed: 32658072
Cell. 2011 Nov 11;147(4):742-58
pubmed: 22078876
Signal Transduct Target Ther. 2022 Aug 13;7(1):286
pubmed: 35963853
Toxicol Pathol. 2007 Jun;35(4):495-516
pubmed: 17562483
Cell Death Dis. 2014 Aug 21;5:e1384
pubmed: 25144719
Cancer Lett. 2016 Oct 10;381(1):269-77
pubmed: 27461582
Cancer Res. 2009 Apr 1;69(7):2809-16
pubmed: 19339267
Nature. 2016 Aug 11;536(7615):215-8
pubmed: 27487218
Nanotheranostics. 2021 Apr 15;5(4):378-390
pubmed: 33912378
Histopathology. 2022 Sep;81(3):297-309
pubmed: 35583805
Int J Mol Sci. 2020 Nov 22;21(22):
pubmed: 33266496
Science. 2015 Oct 16;350(6258):328-34
pubmed: 26405229
BMC Gastroenterol. 2020 Jun 26;20(1):202
pubmed: 32590950
Am J Gastroenterol. 1990 Apr;85(4):350-5
pubmed: 2183589
Mod Pathol. 2017 Dec;30(12):1760-1772
pubmed: 28776573
Semin Cell Dev Biol. 2021 Jan;109:106-113
pubmed: 32988742
Clin Cancer Res. 2019 Apr 1;25(7):2185-2193
pubmed: 30617137
Gastroenterology. 2011 Oct;141(4):1486-97, 1497.e1-14
pubmed: 21704588
Virchows Arch. 2016 Nov;469(5):523-532
pubmed: 27591765
Nat Rev Gastroenterol Hepatol. 2020 Mar;17(3):153-168
pubmed: 32005945
Cells. 2019 Nov 21;8(12):
pubmed: 31766571
Endosc Ultrasound. 2017 Dec;6(Suppl 3):S58-S61
pubmed: 29387690
Nature. 2016 Apr 14;532(7598):245-9
pubmed: 27049944
Ir J Med Sci. 2017 Feb;186(1):57-62
pubmed: 27156054
Cell Death Dis. 2022 Oct 25;13(10):897
pubmed: 36284087
J Hematol Oncol. 2022 Dec 8;15(1):174
pubmed: 36482419
Front Med (Lausanne). 2022 Apr 11;9:845271
pubmed: 35479956
Am J Surg Pathol. 2009 Aug;33(8):1164-72
pubmed: 19440145
Cell Biol Int. 2021 Oct;45(10):2017-2030
pubmed: 34189798
Cancer Cell. 2016 Nov 14;30(5):668-681
pubmed: 27846389
Cancer Res. 2014 Jun 1;74(11):2913-21
pubmed: 24840647
Clin Cancer Res. 2017 Oct 1;23(19):5959-5969
pubmed: 28600474
Cell. 2016 Sep 8;166(6):1485-1499.e15
pubmed: 27569912
PLoS Med. 2009 Apr 7;6(4):e1000046
pubmed: 19360088
Nat Biomed Eng. 2023 Jan;7(1):24-37
pubmed: 36509913
Oxid Med Cell Longev. 2018 Jan 31;2018:3537471
pubmed: 29636841
World J Gastrointest Oncol. 2020 Feb 15;12(2):173-181
pubmed: 32104548
Mol Cancer. 2018 Jul 30;17(1):108
pubmed: 30060755
Science. 1996 Jan 19;271(5247):350-3
pubmed: 8553070
Am J Surg Pathol. 2004 Jul;28(7):839-48
pubmed: 15223952
Ann Oncol. 2012 Jul;23(7):1880-8
pubmed: 22104574
Best Pract Res Clin Gastroenterol. 2010 Jun;24(3):349-58
pubmed: 20510834
Cell Mol Life Sci. 2016 Jun;73(11-12):2405-10
pubmed: 27048813
J Exp Clin Cancer Res. 2018 Dec 19;37(1):319
pubmed: 30567565
Oncoimmunology. 2016 Mar 10;5(6):e1149673
pubmed: 27471616
Transl Gastroenterol Hepatol. 2019 Jun 27;4:50
pubmed: 31304427
J Clin Transl Res. 2021 Mar 24;7(2):257-262
pubmed: 34104829
Case Rep Gastroenterol. 2016 Oct 18;10(3):605-612
pubmed: 27920649
Cancer Cell. 2018 Nov 12;34(5):757-774.e7
pubmed: 30423296
Biomed Res Int. 2014;2014:474905
pubmed: 24783207
Mod Pathol. 2015 Feb;28(2):248-60
pubmed: 25103069
Cancer Treat Rev. 2021 Nov;100:102262
pubmed: 34418781
Cells. 2020 Aug 01;9(8):
pubmed: 32752206
Annu Rev Pathol. 2017 Jan 24;12:103-130
pubmed: 27959630
Cell Death Dis. 2016 Jan 14;7:e2051
pubmed: 26775703
J Clin Oncol. 2015 Oct 1;33(28):3124-9
pubmed: 25940717
Am J Pathol. 1993 May;142(5):1534-43
pubmed: 8494051
Am J Pathol. 1993 Aug;143(2):545-54
pubmed: 8342602
J Clin Invest. 2016 Nov 1;126(11):4140-4156
pubmed: 27701147
Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21188-93
pubmed: 22158988
Cell Rep. 2017 Apr 4;19(1):175-187
pubmed: 28380356
Mol Cell Oncol. 2015 May 26;3(1):e1035690
pubmed: 27308554
Sci Transl Med. 2011 Jul 20;3(92):92ra66
pubmed: 21775669
Gastroenterology. 2020 Feb;158(3):573-582.e2
pubmed: 31678302
Nat Commun. 2019 Sep 5;10(1):4016
pubmed: 31488817
Exp Mol Med. 2022 Oct;54(10):1695-1704
pubmed: 36224345
Cell Mol Life Sci. 2016 Jun;73(11-12):2177-81
pubmed: 27066893
CA Cancer J Clin. 2023 Jan;73(1):17-48
pubmed: 36633525
Cell. 2000 Jan 7;100(1):57-70
pubmed: 10647931
Cell Death Dis. 2017 Oct 5;8(10):e3084
pubmed: 28981102
Int J Oncol. 2000 Sep;17(3):535-41
pubmed: 10938395
World J Gastroenterol. 2018 Nov 21;24(43):4846-4861
pubmed: 30487695
Lab Invest. 2021 Feb;101(2):177-192
pubmed: 33009500
Signal Transduct Target Ther. 2021 Jul 5;6(1):249
pubmed: 34219130
Nat Rev Immunol. 2019 Nov;19(11):665-674
pubmed: 31570879
Exp Mol Pathol. 2012 Dec;93(3):345-9
pubmed: 22902940
Cell Stress. 2019 Dec 19;4(1):1-8
pubmed: 31922095
Cancer Lett. 2020 Oct 10;490:20-30
pubmed: 32585413
J Pathol. 2012 Sep;228(1):113-8
pubmed: 22374786
Gastroenterology. 2018 Mar;154(4):1061-1065
pubmed: 29158190
J Hematol Oncol. 2020 Oct 2;13(1):130
pubmed: 33008426
Cell Death Dis. 2015 Feb 12;6:e1636
pubmed: 25675296
Cancer Biol Ther. 2016 Sep;17(9):899-910
pubmed: 27434654
Cell Death Differ. 2018 Mar;25(3):486-541
pubmed: 29362479
Cell Death Differ. 2016 Jan;23(1):76-88
pubmed: 26024392
Surgery. 2010 Jun;147(6):812-7
pubmed: 20060146
Cell Res. 2015 Jun;25(6):707-25
pubmed: 25952668
Gastrointest Endosc. 2013 Apr;77(4):669-70
pubmed: 23498145
World J Gastroenterol. 2016 Nov 28;22(44):9694-9705
pubmed: 27956793
J Biochem Mol Toxicol. 2021 Apr;35(4):e22708
pubmed: 33491255
Nat Commun. 2020 Aug 14;11(1):4085
pubmed: 32796935