In Silico Analysis, Anticonvulsant Activity, and Toxicity Evaluation of Schisandrin B in Zebrafish Larvae and Mice.

Animals Mice Anticonvulsants / toxicity Zebrafish Molecular Docking Simulation Pentylenetetrazole / toxicity Seizures / chemically induced Glutamic Acid Larva Receptors, GABA-A
local field potential recordings mice molecular modeling pentylenetetrazole schisandrin B seizures toxicity zebrafish

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
18 Aug 2023
Historique:
received: 23 07 2023
revised: 16 08 2023
accepted: 16 08 2023
medline: 28 8 2023
pubmed: 26 8 2023
entrez: 26 8 2023
Statut: epublish

Résumé

The aim of this study is to evaluate the anticonvulsant potential of schisandrin B, a main ingredient of

Identifiants

DOI: 10.3390/ijms241612949 PMID: 37629132 PMC: PMC10455331
pubmed: 37629132
pii: ijms241612949
doi: 10.3390/ijms241612949
pmc: PMC10455331
pii:
doi:

Substances chimiques

Anticonvulsants 0
schizandrin B 02XA4X3KZW
Pentylenetetrazole WM5Z385K7T
Glutamic Acid 3KX376GY7L
Receptors, GABA-A 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Références

J Med Chem. 2006 Oct 19;49(21):6177-96
pubmed: 17034125
Arch Pharm (Weinheim). 2021 May;354(5):e2000414
pubmed: 33543794
Mol Neurobiol. 2021 Feb;58(2):877-894
pubmed: 33057948
J Med Chem. 2014 Apr 10;57(7):3005-10
pubmed: 24601604
Exp Ther Med. 2020 Dec;20(6):142
pubmed: 33093880
Adv Sci (Weinh). 2020 Jul 01;7(16):2001048
pubmed: 32832360
Eur J Med Chem. 2004 Mar;39(3):235-40
pubmed: 15051171
Int J Mol Sci. 2020 Apr 05;21(7):
pubmed: 32260588
J Med Chem. 2023 Apr 13;66(7):4434-4467
pubmed: 37012671
J Pharm Biomed Anal. 2013 May 5;78-79:136-40
pubmed: 23474814
Front Neurosci. 2021 Jul 02;15:682821
pubmed: 34276290
Behav Brain Res. 2012 Mar 17;228(2):367-74
pubmed: 22197677
J Ethnopharmacol. 2019 Jun 12;237:354-365
pubmed: 30844489
Neuropsychiatr Dis Treat. 2017 Feb 23;13:585-596
pubmed: 28260906
J Ethnopharmacol. 2013 Mar 7;146(1):347-54
pubmed: 23333311
Int J Mol Sci. 2023 May 23;24(11):
pubmed: 37298103
Cells. 2020 May 16;9(5):
pubmed: 32429356
Neuron. 2021 Aug 4;109(15):2443-2456.e5
pubmed: 34186027
Appl Physiol Nutr Metab. 2019 Jan;44(1):1-6
pubmed: 29742356
Nature. 2019 Jan;565(7740):454-459
pubmed: 30602790
Eur J Pharm Biopharm. 2018 Jun;127:72-84
pubmed: 29427629
J Chromatogr A. 1996 Mar 29;728(1-2):113-28
pubmed: 8673230
Pharm Biol. 2015;53(9):1329-38
pubmed: 25856720
ACS Chem Neurosci. 2019 Feb 20;10(2):996-1007
pubmed: 29944335
Seizure. 2020 Dec;83:216-222
pubmed: 33127274
Neurol Res. 2020 Aug;42(8):693-702
pubmed: 32657248
Eur J Med Chem. 2021 Jan 1;209:112916
pubmed: 33328102
Ann Transl Med. 2021 Oct;9(19):1500
pubmed: 34805362
Med Sci Monit. 2018 Feb 28;24:1219-1224
pubmed: 29487280
Front Neurol. 2021 Jun 22;12:674483
pubmed: 34239494
Eur J Med Chem. 2001 Sep;36(9):719-30
pubmed: 11672881
J Med Chem. 1996 Nov 22;39(24):4750-5
pubmed: 8941388
Neurosci Biobehav Rev. 2019 Dec;107:6-22
pubmed: 31381931
ChemMedChem. 2022 Aug 3;17(15):e202200238
pubmed: 35610178
J Chem Inf Model. 2021 Oct 25;61(10):5293-5303
pubmed: 34528431
Nature. 2020 Aug;584(7819):125-129
pubmed: 32528175
J Pharm Biomed Anal. 2006 Apr 11;41(1):228-32
pubmed: 16406443
J Neurosci. 1988 Nov;8(11):4027-37
pubmed: 3183711
EXCLI J. 2012 Jan 20;11:1-6
pubmed: 27298604
Anal Chem. 1995 Feb 15;67(4):755-62
pubmed: 7702190
Zebrafish. 2017 Aug;14(4):322-330
pubmed: 28488933
Molecules. 2017 Feb 22;22(2):
pubmed: 28241450
Epilepsia. 2001;42 Suppl 3:8-12
pubmed: 11520315
J Pharmacol Exp Ther. 2005 Jun;313(3):1254-62
pubmed: 15743928
Mol Neurobiol. 2020 Apr;57(4):1904-1916
pubmed: 31875924
Neural Regen Res. 2017 Oct;12(10):1733-1741
pubmed: 29171440
Biomed Res Int. 2014;2014:876712
pubmed: 24605339
Toxins (Basel). 2022 Jul 29;14(8):
pubmed: 36006180
Pharmacol Rev. 2011 Jun;63(2):316-47
pubmed: 21444610
Seizure. 2007 Oct;16(7):636-44
pubmed: 17570689
Biomedicines. 2019 Mar 26;7(1):
pubmed: 30917585
Eur J Pharmacol. 1985 Oct 29;117(1):121-5
pubmed: 4085541
Int J Mol Sci. 2018 Jul 06;19(7):
pubmed: 29986408
Int J Mol Sci. 2021 Jul 20;22(14):
pubmed: 34299361
Biol Pharm Bull. 2010;33(5):825-9
pubmed: 20460761
PLoS One. 2021 Jun 4;16(6):e0239111
pubmed: 34086671
J Chem Inf Comput Sci. 2000 Nov-Dec;40(6):1349-55
pubmed: 11128093
Biomed Pharmacother. 2018 Jul;103:509-516
pubmed: 29677536
Methods Cell Biol. 2016;132:359-99
pubmed: 26928552
Expert Opin Drug Discov. 2015 May;10(5):449-61
pubmed: 25835573
J Ethnopharmacol. 2021 Feb 10;266:113426
pubmed: 33007392
Adv Drug Deliv Rev. 2001 Mar 1;46(1-3):3-26
pubmed: 11259830
J Med Chem. 2006 Dec 28;49(26):7559-83
pubmed: 17181137
Lancet Neurol. 2012 Sep;11(9):792-802
pubmed: 22832500
Evid Based Complement Alternat Med. 2021 Aug 4;2021:6422451
pubmed: 34394390
Free Radic Res. 2011 Aug;45(8):950-8
pubmed: 21615274
Biomed Res Int. 2017;2017:4237973
pubmed: 28706944
PLoS One. 2013 Oct 16;8(10):e77548
pubmed: 24147021
Epilepsia. 2021 Sep;62(9):e147-e152
pubmed: 34331457
Nat Struct Mol Biol. 2022 Jun;29(6):507-518
pubmed: 35637422
Epilepsy Behav. 2005 Sep;7(2):161-71
pubmed: 16054870
Biomed Chromatogr. 2018 Feb;32(2):
pubmed: 28833320
Arch Pharm (Weinheim). 2019 May;352(5):e1800373
pubmed: 31025433
J Pharm Sci. 1997 Mar;86(3):310-5
pubmed: 9050798
Curr Drug Targets. 2021;22(3):356-367
pubmed: 33023444
PLoS One. 2013;8(1):e54166
pubmed: 23342097
Neuroscience. 2005;131(3):759-68
pubmed: 15730879
Chemosphere. 2022 May;295:133863
pubmed: 35124091
Brain Res. 1991 Jul 12;553(2):181-7
pubmed: 1681980
Trends Neurosci. 2001 Jan;24(1):47-53
pubmed: 11163887
Fitoterapia. 2014 Jul;96:123-30
pubmed: 24785966
Oxid Med Cell Longev. 2020 Mar 14;2020:2172740
pubmed: 32256947
Eur J Neurosci. 1993 Nov 1;5(11):1545-50
pubmed: 7904524
Neuropharmacology. 2016 Sep;108:292-304
pubmed: 27085605
Cell. 2020 Sep 17;182(6):1574-1588.e19
pubmed: 32946782
Bioorg Med Chem. 2010 Oct 1;18(19):7078-84
pubmed: 20810286
J Chem Inf Comput Sci. 2002 May-Jun;42(3):651-66
pubmed: 12086527
J Pharm Biomed Anal. 2014 Jan;88:416-22
pubmed: 24176746
Curr Top Med Chem. 2013;13(7):813-20
pubmed: 23578025
Neurol Res. 2019 Aug;41(8):749-761
pubmed: 31038018
Int J Pharm. 2007 Mar 21;333(1-2):127-35
pubmed: 17095172
Biomed Pharmacother. 2015 Oct;75:165-72
pubmed: 26282218
J Chromatogr A. 2001 Apr 20;914(1-2):233-44
pubmed: 11358218
Pharm Res. 2008 Aug;25(8):1737-50
pubmed: 18058202
Neurosci Biobehav Rev. 2020 Sep;116:1-20
pubmed: 32544542
Pharmaceuticals (Basel). 2010 Jul 05;3(7):2090-2110
pubmed: 27713344
Molecules. 2022 Oct 01;27(19):
pubmed: 36235029
Front Physiol. 2022 Apr 11;13:827282
pubmed: 35480044
Br J Pharmacol. 2015 May;172(10):2479-92
pubmed: 25573619
Synapse. 1990;5(2):113-9
pubmed: 2137942
Neurochem Res. 2019 May;44(5):1043-1055
pubmed: 30689162
Int J Mol Sci. 2022 Sep 07;23(18):
pubmed: 36142236
Curr Psychiatry Rep. 2019 Apr 29;21(6):40
pubmed: 31037466
Brain Res Bull. 2019 Sep;151:46-54
pubmed: 30468847
J Med Chem. 1988 Mar;31(3):656-71
pubmed: 2894467

Auteurs

Dorota Nieoczym (D)

Department of Animal Physiology and Pharmacology, Institute of Biological Sciences, Faculty of Biology and Biotechnology, Maria Curie-Skłodowska University, Akademicka 19, 20-033 Lublin, Poland.
ORCID: 0000-0002-9446-7343

Nancy Saana Banono (NS)

Chemical Neuroscience Group, Centre for Molecular Medicine Norway, University of Oslo, Gaustadalleen 21, Forskningsparken, 0349 Oslo, Norway.
ORCID: 0000-0002-3061-1633

Katarzyna Stępnik (K)

Department of Physical Chemistry, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Skłodowska University, Pl. M. Curie-Skłodowskiej 3/243, 20-031 Lublin, Poland.

Agnieszka A Kaczor (AA)

Department of Synthesis and Chemical Technology of Pharmaceutical Substances with Computer Modeling Laboratory, Faculty of Pharmacy, Medical University of Lublin, 4A Chodzki St., 20-093 Lublin, Poland.
ORCID: 0000-0001-8679-9623

Przemysław Szybkowski (P)

Department of Experimental and Clinical Pharmacology, Medical University of Lublin, Jaczewskiego St. 8b, 20-090 Lublin, Poland.
Clinical Provincial Hospital No. 2 St. Jadwiga Krolowej in Rzeszow, Lwowska St. 60, 35-301 Rzeszow, Poland.

Camila Vicencio Esguerra (CV)

Chemical Neuroscience Group, Centre for Molecular Medicine Norway, University of Oslo, Gaustadalleen 21, Forskningsparken, 0349 Oslo, Norway.

Wirginia Kukula-Koch (W)

Department of Pharmacognosy with Medicinal Plants Garden, Medical University of Lublin, Chodźki St. 1, 20-093 Lublin, Poland.
ORCID: 0000-0001-7076-600X

Kinga Gawel (K)

Department of Experimental and Clinical Pharmacology, Medical University of Lublin, Jaczewskiego St. 8b, 20-090 Lublin, Poland.
ORCID: 0000-0001-8857-847X

Articles similaires

Evaluating the efficacy of telesurgery with dual console SSI Mantra Surgical Robotic System: experiment on animal model and clinical trials.

Sudhir Prem Srivastava, Vishwajyoti Pascual Srivastava, Avinesh Singh et al.
1.00
Robotic Surgical Procedures Animals Humans Telemedicine Models, Animal

Odour generalisation and detection dog training.

Lyn Caldicott, Thomas W Pike, Helen E Zulch et al.
1.00
Animals Odorants Dogs Generalization, Psychological Smell

FBXO22 inhibits colitis and colorectal carcinogenesis by regulating the degradation of the S2448-phosphorylated form of mTOR.

Minle Li, Xuan Chen, Pengfei Qu et al.
1.00
Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice

Use of organic material provided by an automatic enrichment device by weaner pigs and its influence on tail lesions.

Philipp Heseker, Jeanette Probst, Stefanie Ammer et al.
1.00
Animals Tail Swine Behavior, Animal Animal Husbandry

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › In Silico Analysis, Anticonvulsant Activity,...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › In Silico Analysis, Anticonvulsant Activity,...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents du système nerveux central › Anticonvulsivants › In Silico Analysis, Anticonvulsant Activity,...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Poissons › Cypriniformes › Cyprinidae › Danio zébré › In Silico Analysis, Anticonvulsant Activity,...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de docking moléculaire › In Silico Analysis, Anticonvulsant Activity,...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Azépines › Pentétrazol › In Silico Analysis, Anticonvulsant Activity,...
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Manifestations neurologiques › Crises épileptiques › In Silico Analysis, Anticonvulsant Activity,...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Acides aminés excitateurs › Acide glutamique › In Silico Analysis, Anticonvulsant Activity,...
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Morphogenèse › Métamorphose biologique › Étapes du cycle de vie › Larve › In Silico Analysis, Anticonvulsant Activity,...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux neuromédiateurs › Récepteurs aux acides aminés › Récepteurs GABA › Récepteurs GABA-A › In Silico Analysis, Anticonvulsant Activity,...