Periodontal Disease and Its Association with Metabolic Syndrome-A Comprehensive Review.

cardiovascular disease diabetes mellitus dyslipidemia insulin resistance metabolic syndrome obesity osteoporosis periodontitis

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
21 Aug 2023
Historique:
received: 27 06 2023
revised: 07 08 2023
accepted: 17 08 2023
medline: 28 8 2023
pubmed: 26 8 2023
entrez: 26 8 2023
Statut: epublish

Résumé

Periodontal disease is a complex and progressive chronic inflammatory condition that leads to the loss of alveolar bone and teeth. It has been associated with various systemic diseases, including diabetes mellitus and obesity, among others. Some of these conditions are part of the metabolic syndrome cluster, a group of interconnected systemic diseases that significantly raise the risk of cardiovascular diseases, diabetes mellitus, and stroke. The metabolic syndrome cluster encompasses central obesity, dyslipidemia, insulin resistance, and hypertension. In this review, our objective is to investigate the correlation between periodontal disease and the components and outcomes of the metabolic syndrome cluster. By doing so, we aim to gain insights into the fundamental mechanisms that link each systemic condition with the metabolic syndrome. This deeper understanding of the interplay between these conditions and periodontal disease can pave the way for more effective treatments that take into account the broader impact of managing periodontal disease on the comprehensive treatment of systemic diseases, and vice versa.

Identifiants

pubmed: 37629193
pii: ijms241613011
doi: 10.3390/ijms241613011
pmc: PMC10455993
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Références

Med Oral Patol Oral Cir Bucal. 2017 Sep 1;22(5):e586-e594
pubmed: 28809366
BMC Gastroenterol. 2012 Feb 16;12:16
pubmed: 22340817
Oral Dis. 2016 Oct;22(7):673-80
pubmed: 27265537
Int Dent J. 2017 Apr;67(2):67-77
pubmed: 27861820
J Clin Periodontol. 2018 Jun;45 Suppl 20:S162-S170
pubmed: 29926490
Int J Environ Res Public Health. 2020 Jul 29;17(15):
pubmed: 32751340
J Clin Periodontol. 2013 Nov;40(11):994-1000
pubmed: 24007401
Diabetes Care. 2005 Nov;28(11):2777-9
pubmed: 16249557
J Am Coll Cardiol. 2017 Jul 4;70(1):1-25
pubmed: 28527533
J Clin Periodontol. 2020 Mar;47(3):268-288
pubmed: 32011025
Front Endocrinol (Lausanne). 2022 Oct 24;13:999455
pubmed: 36353241
Periodontol 2000. 2016 Oct;72(1):76-95
pubmed: 27501492
J Clin Med. 2021 Jan 06;10(2):
pubmed: 33419028
Int J Dent Hyg. 2018 Nov;16(4):484-491
pubmed: 29900658
Cochrane Database Syst Rev. 2021 Dec 12;12:CD009409
pubmed: 34897644
Aging (Albany NY). 2020 Jul 7;12(13):13090-13114
pubmed: 32634783
Periodontol 2000. 2020 Feb;82(1):214-224
pubmed: 31850631
J Periodontal Res. 2016 Oct;51(5):604-12
pubmed: 26667347
Braz Dent J. 2022 Sep-Oct;33(5):64-73
pubmed: 36287500
ISME J. 2017 Sep;11(9):2075-2089
pubmed: 28534880
Clin Oral Investig. 2022 Sep;26(9):5557-5574
pubmed: 35716205
Diabetes Metab J. 2012 Dec;36(6):404-11
pubmed: 23275933
Cochrane Database Syst Rev. 2022 Apr 14;4:CD004714
pubmed: 35420698
J Contemp Dent Pract. 2013 Sep 01;14(5):785-9
pubmed: 24685775
J Oral Rehabil. 2016 Jan;43(1):31-8
pubmed: 26332936
Am J Hypertens. 2016 Mar;29(3):388-96
pubmed: 26208668
Front Physiol. 2021 Jan 14;11:609614
pubmed: 33519515
J Clin Periodontol. 2013 Jul;40(7):681-7
pubmed: 23639076
Oral Dis. 2012 Apr;18(3):299-306
pubmed: 22151458
J Periodontol. 2012 Apr;83(4):426-34
pubmed: 21859322
J Clin Periodontol. 2010 Jul;37(7):601-8
pubmed: 20492076
J Periodontol. 2014 Nov;85(11):1629-36
pubmed: 24921432
Nat Rev Endocrinol. 2020 Mar;16(3):177-189
pubmed: 32020062
Microb Pathog. 2019 Mar;128:215-229
pubmed: 30625362
Arch Oral Biol. 2014 Aug;59(8):855-70
pubmed: 24880501
J Clin Periodontol. 2012 Feb;39(2):107-14
pubmed: 22150475
BMJ Open Diabetes Res Care. 2021 Apr;9(1):
pubmed: 33879517
J Clin Periodontol. 2017 Mar;44(3):266-274
pubmed: 28036104
J Periodontol. 2013 Apr;84 Suppl 4S:S24-S29
pubmed: 29537596
J Clin Periodontol. 2016 Dec;43(12):1003-1012
pubmed: 27717180
Periodontol 2000. 2021 Oct;87(1):50-75
pubmed: 34463996
Curr Cardiol Rev. 2014 Nov;10(4):355-61
pubmed: 24739001
Front Cell Infect Microbiol. 2022 Dec 02;12:1061125
pubmed: 36530437
Cardiovasc Res. 2020 Jan 1;116(1):28-39
pubmed: 31549149
J Periodontol. 2015 Nov;86(11):1201-11
pubmed: 26205747
Blood Press. 2013 Aug;22(4):193-278
pubmed: 23777479
Int J Environ Res Public Health. 2022 Oct 04;19(19):
pubmed: 36231983
Colomb Med (Cali). 2013 Jun 30;44(2):80-6
pubmed: 24892452
Adv Med Sci. 2014 Mar;59(1):126-31
pubmed: 24797988
Mediators Inflamm. 2013;2013:728987
pubmed: 24068858
J Clin Periodontol. 2014 Aug;41(8):772-8
pubmed: 24813869
Clin Oral Investig. 2021 Jun;25(6):3719-3727
pubmed: 33226499
Eur J Med Res. 2022 Sep 16;27(1):181
pubmed: 36114562
J Periodontol. 2009 Feb;80(2):267-73
pubmed: 19186967
Nutr Metab (Lond). 2012 Sep 25;9(1):88
pubmed: 23009606
J Diabetes Res. 2017;2017:2643079
pubmed: 29138754
J Clin Periodontol. 2018 Jun;45(6):650-662
pubmed: 29125699
J Indian Soc Periodontol. 2013 Sep;17(5):597-600
pubmed: 24174752
J Periodontol. 2013 Jan;84(1):13-23
pubmed: 22348694
Int J Mol Sci. 2019 Mar 20;20(6):
pubmed: 30897827
J Clin Endocrinol Metab. 2013 Mar;98(3):913-20
pubmed: 23386648
Diabetol Metab Syndr. 2019 Dec 30;11:113
pubmed: 31892956
J Clin Periodontol. 2015 Mar;42(3):247-61
pubmed: 25580635
J Clin Periodontol. 2015 Jun;42(6):495-505
pubmed: 25952821
Clin Oral Investig. 2022 Oct;26(10):6139-6149
pubmed: 35624385
Diabetologia. 2012 Jan;55(1):21-31
pubmed: 22057194
Med Oral Patol Oral Cir Bucal. 2017 Nov 1;22(6):e708-e715
pubmed: 29053651
Compr Physiol. 2013 Jan;3(1):1-58
pubmed: 23720280
Periodontol 2000. 2007;43:254-66
pubmed: 17214843
Diabetes Res Clin Pract. 2022 Dec;194:110150
pubmed: 36375565
Circ Res. 2010 Oct 29;107(9):1058-70
pubmed: 21030723
J Dent Res. 2015 Feb;94(2):362-70
pubmed: 25503900
Diabetes Care. 2012 Nov;35(11):2235-42
pubmed: 22837370
Int J Obes (Lond). 2010 Dec;34(12):1695-705
pubmed: 20514047
J Clin Periodontol. 2018 Feb;45(2):188-195
pubmed: 29277978
PLoS One. 2018 Oct 1;13(10):e0204724
pubmed: 30273364
Front Endocrinol (Lausanne). 2020 Jun 09;11:336
pubmed: 32582028
Can J Dent Hyg. 2022 Feb 1;56(1):22-30
pubmed: 35401764
J Clin Periodontol. 2023 Jan;50(1):11-21
pubmed: 36053828
J Periodontol. 2010 Dec;81(12):1708-24
pubmed: 20722533
Antioxidants (Basel). 2021 Oct 30;10(11):
pubmed: 34829612
Clin Oral Investig. 2012 Jun;16(3):727-34
pubmed: 21556849
Am J Med Sci. 2013 Apr;345(4):271-273
pubmed: 23531957
J Educ Health Promot. 2018 Dec 28;7:152
pubmed: 30788374
Int J Oral Sci. 2015 Jun 26;7(2):63-72
pubmed: 25857702
JAMA. 2001 May 16;285(19):2486-97
pubmed: 11368702
Int J Environ Res Public Health. 2021 Aug 07;18(16):
pubmed: 34444121
Cochrane Database Syst Rev. 2015 Nov 06;(11):CD004714
pubmed: 26545069
Gerodontology. 2016 Jun;33(2):193-200
pubmed: 24924482
J Clin Periodontol. 2016 Jul;43(7):557-65
pubmed: 26970086
Diabetes Care. 2003 Nov;26(11):3160-7
pubmed: 14578255
J Med Life. 2020 Jul-Sep;13(3):289-292
pubmed: 33072198
Mediators Inflamm. 2015;2015:379626
pubmed: 26347009
Circulation. 2005 Oct 25;112(17):2735-52
pubmed: 16157765
J Hypertens. 2018 Oct;36(10):1953-2041
pubmed: 30234752
J Diabetes Res. 2014;2014:137919
pubmed: 25019091
J Periodontol. 2021 Oct;92(10):1410-1419
pubmed: 33386623
J Appl Oral Sci. 2013 Jan-Feb;21(1):1-12
pubmed: 23559105
Int J Environ Res Public Health. 2021 Oct 22;18(21):
pubmed: 34769630
Clin Exp Dent Res. 2019 Mar 09;5(3):243-249
pubmed: 31249705
Br Dent J. 2019 Oct;227(7):577-584
pubmed: 31605062
ISME J. 2020 Feb;14(2):519-530
pubmed: 31673077
Bone. 2019 Jan;118:2-7
pubmed: 29782940

Auteurs

Itay Aizenbud (I)

Medical Corps, Israel Defense Forces, Jerusalem 60930, Israel.

Asaf Wilensky (A)

Department of Periodontology, Hadassah Medical Center, Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem 91120, Israel.

Galit Almoznino (G)

Faculty of Dental Medicine, Hebrew University of Jerusalem, Israel, Big Biomedical Data Research Laboratory, Dean's Office, Hadassah Medical Center, Jerusalem 91120, Israel.
Faculty of Dental Medicine, Hebrew University of Jerusalem, Department of Oral Medicine, Sedation & Maxillofacial Imaging, Hadassah Medical Center, Jerusalem 91120, Israel.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH