Dietary Flaxseed and Flaxseed Oil Differentially Modulate Aspects of the Microbiota Gut-Brain Axis Following an Acute Lipopolysaccharide Challenge in Male C57Bl/6 Mice.

LPS PICRUSt2 Qiime2 flaxseed flaxseed oil gut–brain axis inflammation lipopolysaccharide microbiota microbiota gut–brain axis

Journal

Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595

Informations de publication

Date de publication:
11 Aug 2023
Historique:
received: 15 07 2023
revised: 03 08 2023
accepted: 05 08 2023
medline: 28 8 2023
pubmed: 26 8 2023
entrez: 26 8 2023
Statut: epublish

Résumé

The microbiota gut-brain axis (mGBA) is an important contributor to mental health and neurological and mood disorders. Lipopolysaccharides (LPS) are endotoxins that are components of Gram-negative bacteria cell walls and have been widely shown to induce both systemic and neuro-inflammation. Flaxseed (

Identifiants

pubmed: 37630732
pii: nu15163542
doi: 10.3390/nu15163542
pmc: PMC10459276
pii:
doi:

Substances chimiques

Linseed Oil 8001-26-1
Lipopolysaccharides 0
Interleukin-10 130068-27-8
methylglyoxal bis(3-aminopropylamidinohydrazone) 121496-63-7
Tumor Necrosis Factor-alpha 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Natural Sciences and Engineering Research Council
ID : 2018-06545

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Auteurs

Dawson B H Livingston (DBH)

Faculty of Medicine, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H 8L1, Canada.

Allison Sweet (A)

Faculty of Medicine, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H 8L1, Canada.

Alexane Rodrigue (A)

Faculty of Medicine, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H 8L1, Canada.

Lalit Kishore (L)

Faculty of Health Science, School of Nutrition Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada.

Julia Loftus (J)

Faculty of Science, Department of Biochemistry, University of Ottawa, Ottawa, ON K1N 6N5, Canada.

Farida Ghali (F)

Faculty of Health Science, School of Nutrition Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada.

Salma Mahmoodianfard (S)

Faculty of Health Science, School of Human Kinetics, University of Ottawa, Ottawa, ON K1N 6N5, Canada.

Colleen Celton (C)

Faculty of Science, Department of Chemistry, Carleton University, Ottawa, ON K1S 5B6, Canada.

Farah Hosseinian (F)

Faculty of Science, Department of Chemistry, Carleton University, Ottawa, ON K1S 5B6, Canada.
Faculty of Science, Institute of Biochemistry, Carleton University, Ottawa, ON K1S 5B6, Canada.

Krista A Power (KA)

Faculty of Medicine, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON K1H 8L1, Canada.
Faculty of Health Science, School of Nutrition Sciences, University of Ottawa, Ottawa, ON K1N 6N5, Canada.

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Classifications MeSH