Stabilization of Essential Oil: Polysaccharide-Based Drug Delivery System with Plant-like Structure Based on Biomimetic Concept.

biomimetic drug delivery system emulsion encapsulation essential oil polysaccharides solidification stability

Journal

Polymers
ISSN: 2073-4360
Titre abrégé: Polymers (Basel)
Pays: Switzerland
ID NLM: 101545357

Informations de publication

Date de publication:
08 Aug 2023
Historique:
received: 22 06 2023
revised: 21 07 2023
accepted: 23 07 2023
medline: 26 8 2023
pubmed: 26 8 2023
entrez: 26 8 2023
Statut: epublish

Résumé

Essential oils (EOs) have stability problems, including volatility, oxidation, photosensitivity, heat sensitivity, humidity sensitivity, pH sensitivity, and ion sensitivity. A drug delivery system is an effective way to stabilize EOs, especially due to the protective effect of polymeric drug carriers. Polysaccharides are frequently employed as drug carrier materials because they are highly safe, come in a variety of forms, and have plentiful sources. Interestingly, the EO drug delivery system is based on the biomimetic concept since it corresponds to the structure of plant tissue. In this paper, we associate the biomimetic plant-like structures of the EO drug delivery system with the natural forms of EO in plant tissues, and summarize the characteristics of polysaccharide-based drug carriers for EO protection. Thus, we highlight the research progress on polysaccharides and their modified materials, including gum arabic, starch, cellulose, chitosan, sodium alginate, pectin, and pullulan, and their use as biomimetic drug carriers for EO preparations due to their abilities and potential for EO protection.

Identifiants

pubmed: 37631395
pii: polym15163338
doi: 10.3390/polym15163338
pmc: PMC10457915
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Subventions

Organisme : National Natural Science Foundation of China general projects
ID : 82274066
Organisme : National Key Research and Development Program of China
ID : 2022YFC3501705
Organisme : Shanghai Science and Technology Innovation Project
ID : 22S21901200

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Auteurs

Xue-Yee Lim (XY)

School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.

Jing Li (J)

School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.

Hong-Mei Yin (HM)

Jiangsu Kanion Pharmaceuticals Co., Ltd., Lianyungang 222001, China.

Mu He (M)

School of Acupuncture-Moxibustion and Tuina, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.

Ling Li (L)

School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
College of Pharmacy, Anhui University of Chinese Medicine, Hefei 230012, China.

Tong Zhang (T)

School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.

Classifications MeSH