Rendezvous with Vaccinia Virus in the Post-smallpox Era: R&D Advances.
immunomodulation
innovation
monkeypox
poxvirus
purification
safety
smallpox
vaccinia virus
Journal
Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722
Informations de publication
Date de publication:
15 08 2023
15 08 2023
Historique:
received:
28
07
2023
revised:
13
08
2023
accepted:
14
08
2023
medline:
28
8
2023
pubmed:
26
8
2023
entrez:
26
8
2023
Statut:
epublish
Résumé
Smallpox was eradicated in less than 200 years after Edward Jenner's practice of cowpox variolation in 1796. The forty-three years of us living free of smallpox, beginning in 1979, never truly separated us from poxviruses. The recent outbreak of monkeypox in May 2022 might well warn us of the necessity of keeping up both the scientific research and public awareness of poxviruses. One of them in particular, the vaccinia virus (VACV), has been extensively studied as a vector given its broad host range, extraordinary thermal stability, and exceptional immunogenicity. Unceasing fundamental biological research on VACV provides us with a better understanding of its genetic elements, involvement in cellular signaling pathways, and modulation of host immune responses. This enables the rational design of safer and more efficacious next-generation vectors. To address the new technological advancement within the past decade in VACV research, this review covers the studies of viral immunomodulatory genes, modifications in commonly used vectors, novel mechanisms for rapid generation and purification of recombinant virus, and several other innovative approaches to studying its biology.
Identifiants
pubmed: 37632084
pii: v15081742
doi: 10.3390/v15081742
pmc: PMC10457812
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Références
Vaccines (Basel). 2023 Mar 23;11(4):
pubmed: 37112626
Methods Mol Biol. 2019;2023:209-220
pubmed: 31240680
J Gen Virol. 2005 Jul;86(Pt 7):1997-2006
pubmed: 15958679
Lancet. 2013 Mar 23;381(9871):1021-8
pubmed: 23391465
J Virol. 2015 May;89(9):5176-9
pubmed: 25741005
PLoS Pathog. 2008 Feb 8;4(2):e22
pubmed: 18266467
Vaccines (Basel). 2021 Aug 27;9(9):
pubmed: 34579196
Mol Ther Methods Clin Dev. 2021 May 05;21:741-753
pubmed: 34169114
Vaccine. 2006 Mar 15;24(12):2065-70
pubmed: 16337719
Vaccine. 2013 Sep 6;31(39):4220-2
pubmed: 23583893
Curr Genet. 1992 Apr;21(4-5):345-9
pubmed: 1525863
Virology. 2008 Feb 5;371(1):98-107
pubmed: 17950773
PLoS One. 2013 Sep 17;8(9):e74831
pubmed: 24069354
Lancet. 2005 Jan 29-Feb 4;365(9457):398-409
pubmed: 15680454
Biologicals. 2011 Jan;39(1):50-8
pubmed: 21237672
Vaccines (Basel). 2020 Feb 06;8(1):
pubmed: 32041218
Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5995-6000
pubmed: 16581912
Vaccine. 2016 Apr 7;34(16):1915-26
pubmed: 26939903
J Virol. 2014 Mar;88(6):3392-410
pubmed: 24390336
Front Immunol. 2022 Mar 16;13:845887
pubmed: 35371043
NPJ Vaccines. 2022 Jul 25;7(1):83
pubmed: 35879311
Viruses. 2023 May 17;15(5):
pubmed: 37243266
Mol Ther. 2022 May 4;30(5):1885-1896
pubmed: 34687845
Proc Natl Acad Sci U S A. 2022 Jun 14;119(24):e2202069119
pubmed: 35679343
Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):2692-7
pubmed: 10077573
Front Microbiol. 2022 Nov 18;13:967019
pubmed: 36466631
Front Immunol. 2022 Jan 27;12:824728
pubmed: 35154086
Proc Natl Acad Sci U S A. 2021 Jul 13;118(28):
pubmed: 34162739
Nucleic Acids Res. 2008 Jan;36(Database issue):D923-8
pubmed: 18025042
Microorganisms. 2013 Nov 01;1(1):100-121
pubmed: 27694766
Curr Protoc Protein Sci. 2017 Aug 1;89:5.13.1-5.13.18
pubmed: 28762491
PLoS One. 2015 Nov 24;10(11):e0143552
pubmed: 26599077
J Gen Virol. 2002 Apr;83(Pt 4):873-878
pubmed: 11907337
PLoS One. 2017 Mar 3;12(3):e0173056
pubmed: 28257484
PLoS One. 2013 Jun 27;8(6):e66894
pubmed: 23826170
BMC Proc. 2011 Nov 22;5 Suppl 8:P52
pubmed: 22373530
Mol Biol Cell. 2005 Jun;16(6):2822-35
pubmed: 15800065
PLoS Pathog. 2011 Sep;7(9):e1002247
pubmed: 21931555
Vaccine. 2020 Jun 19;38(30):4773-4779
pubmed: 32473878
Vaccine. 2010 Feb 3;28(5):1209-16
pubmed: 19944151
J Gen Virol. 2002 Aug;83(Pt 8):1953-1964
pubmed: 12124459
J Gen Virol. 1998 Feb;79 ( Pt 2):347-52
pubmed: 9472619
Virology. 2003 Feb 1;306(1):181-95
pubmed: 12620810
Nat Biotechnol. 2013 Mar;31(3):233-9
pubmed: 23360965
J Virol. 2017 Apr 13;91(9):
pubmed: 28179536
Sci Transl Med. 2023 Jul 12;15(704):eadf1782
pubmed: 37437014
J Virol. 2004 Oct;78(19):10230-7
pubmed: 15367588
Front Immunol. 2023 Apr 21;14:1182963
pubmed: 37153588
Methods Mol Biol. 2019;2023:221-235
pubmed: 31240681
J Virol. 2019 Feb 19;93(5):
pubmed: 30541829
Microb Biotechnol. 2008 Jan;1(1):2-16
pubmed: 21261817
Vaccine. 2015 Nov 27;33(48):6938-46
pubmed: 26403370
Virology. 2015 May;479-480:619-26
pubmed: 25728299
Front Immunol. 2023 Jul 07;14:1177324
pubmed: 37483628
J Virol. 2012 May;86(9):5026-38
pubmed: 22419805
J Infect Dis. 2011 Jan 1;203(1):95-102
pubmed: 21148501
Nat Commun. 2017 Jun 08;8:15711
pubmed: 28593989
Virol Sin. 2021 Jun;36(3):365-372
pubmed: 32696399
Proc Natl Acad Sci U S A. 1988 Jul;85(14):5166-70
pubmed: 2839833
Virology. 2004 Dec 5;330(1):127-46
pubmed: 15527840
Proc Natl Acad Sci U S A. 1988 Mar;85(5):1394-7
pubmed: 2830617
Viruses. 2018 Feb 28;10(3):
pubmed: 29495547
Vaccine. 2016 Nov 21;34(48):5878-5885
pubmed: 27997338
J Virol. 2018 Mar 14;92(7):
pubmed: 29343579
Methods Mol Biol. 2013;960:219-245
pubmed: 23329491
J Gen Virol. 2013 Sep;94(Pt 9):2070-2081
pubmed: 23761407
Virology. 1992 May;188(1):217-32
pubmed: 1566575
Nucleic Acids Res. 2014 Jan;42(Database issue):D1124-32
pubmed: 24259431
EMBO J. 2008 Aug 6;27(15):2147-57
pubmed: 18636090
Mol Ther Methods Clin Dev. 2020 Mar 30;17:731-738
pubmed: 32346550
PLoS Pathog. 2008 Jan;4(1):e5
pubmed: 18208323
Eff Clin Pract. 2002 Mar-Apr;5(2):84-90
pubmed: 11990216
Semin Cell Dev Biol. 2002 Apr;13(2):121-8
pubmed: 12127145
Adv Drug Deliv Rev. 2009 Jul 2;61(7-8):527-41
pubmed: 19394373
Hum Gene Ther. 1998 Sep 1;9(13):1939-50
pubmed: 9741432
Can J Vet Res. 2011 Oct;75(4):278-84
pubmed: 22468025
Viruses. 2014 Oct 07;6(10):3787-808
pubmed: 25296112
Pathogens. 2023 Jun 23;12(7):
pubmed: 37513714
J Gen Virol. 2013 Nov;94(Pt 11):2367-2392
pubmed: 23999164
J Gen Virol. 2000 May;81(Pt 5):1223-30
pubmed: 10769064
Sci Rep. 2017 Dec 11;7(1):17286
pubmed: 29230061
Vaccine. 2009 Mar 4;27(10):1637-44
pubmed: 19071184
Vaccine. 2010 Sep 14;28(40):6627-36
pubmed: 20659519
Nat Med. 2003 Sep;9(9):1125-30
pubmed: 12925845
Cell Rep Med. 2022 Jul 19;3(7):100685
pubmed: 35858586
Virology. 1991 Mar;181(1):158-64
pubmed: 1994573
Virology. 2007 Oct 25;367(2):398-412
pubmed: 17619043
Virology. 1992 Apr;187(2):643-53
pubmed: 1546459
J Eukaryot Microbiol. 2016 Sep;63(5):679-90
pubmed: 27315329
Front Immunol. 2022 Jun 14;13:841471
pubmed: 35774800
Ann Intern Med. 2003 Mar 18;138(6):488-93
pubmed: 12639083
J Virol. 2012 Dec;86(23):12605-15
pubmed: 22973033
mBio. 2017 Jun 6;8(3):
pubmed: 28588133
Nat Commun. 2023 May 22;14(1):2898
pubmed: 37217469
Mol Ther. 2017 Oct 4;25(10):2332-2344
pubmed: 28720468
Virus Res. 2016 Jul 15;220:1-11
pubmed: 27036935
J Virol. 2022 May 11;96(9):e0038922
pubmed: 35412347
J Infect Dis. 1992 Dec;166(6):1245-50
pubmed: 1431243
Biomedicines. 2021 Aug 31;9(9):
pubmed: 34572308
Front Immunol. 2019 Dec 18;10:2941
pubmed: 31921191
Sci Rep. 2018 Feb 16;8(1):3154
pubmed: 29453406
J Virol. 2005 Sep;79(18):11724-33
pubmed: 16140750
Expert Opin Investig Drugs. 2008 Apr;17(4):555-64
pubmed: 18363519
Mol Biol Cell. 2001 Jul;12(7):2031-46
pubmed: 11452001
Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10775-80
pubmed: 11517299
Nature. 2019 Feb;566(7743):259-263
pubmed: 30728498
MethodsX. 2020 May 15;7:100918
pubmed: 32509537
J Virol. 2018 May 14;92(11):
pubmed: 29514907
Vaccine. 2009 Jan 29;27(5):748-56
pubmed: 19071186
Sci Rep. 2021 Mar 22;11(1):6492
pubmed: 33753816
Vaccines (Basel). 2019 Dec 06;7(4):
pubmed: 31817622
Vaccine. 2019 Apr 3;37(15):2122-2130
pubmed: 30851967
J Gen Virol. 1999 Aug;80 ( Pt 8):2137-2148
pubmed: 10466813
J Virol. 2006 Jun;80(12):6033-47
pubmed: 16731942
Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):E1333-42
pubmed: 25739961
J Exp Med. 2003 Feb 3;197(3):343-51
pubmed: 12566418
J Infect Dis. 1980 Oct;142(4):636-8
pubmed: 7003037
PLoS One. 2011;6(9):e24643
pubmed: 21931792
Mol Ther Methods Clin Dev. 2015 Sep 16;2:15035
pubmed: 26417609
J Virol. 2005 Jun;79(12):7845-51
pubmed: 15919938
J Infect Dis. 2011 Nov;204(9):1395-402
pubmed: 21921208
PLoS One. 2014 Mar 12;9(3):e91516
pubmed: 24621656
Viruses. 2018 Aug 08;10(8):
pubmed: 30096846
Mol Ther Methods Clin Dev. 2017 Sep 30;7:112-122
pubmed: 29085848
EBioMedicine. 2018 Mar;29:146-154
pubmed: 29519670
J Immunol. 2022 Jun 15;208(12):2663-2674
pubmed: 35613727
EMBO J. 2001 Jul 16;20(14):3728-37
pubmed: 11447114
Rev Med Virol. 2019 Jan;29(1):e2009
pubmed: 30260068
Cell. 2013 Sep 12;154(6):1370-9
pubmed: 23992847
Methods Mol Biol. 2019;2023:269-285
pubmed: 31240684
J Gen Virol. 2002 Aug;83(Pt 8):1977-1986
pubmed: 12124461
Vaccine. 2006 Nov 17;24(47-48):7009-22
pubmed: 17052815
Methods Mol Biol. 2004;269:65-76
pubmed: 15114008
J Mol Biol. 2021 Apr 30;433(9):166896
pubmed: 33639215
Viruses. 2017 Dec 27;10(1):
pubmed: 29280955
Lancet Infect Dis. 2022 Jun;22(6):857-866
pubmed: 35305317
PLoS One. 2020 Apr 2;15(4):e0230711
pubmed: 32240193
J Gen Virol. 2008 Dec;89(Pt 12):2992-2997
pubmed: 19008384
J Infect Dis. 1970 Oct;122(4):303-9
pubmed: 4396189
J Exp Med. 2005 Mar 21;201(6):1007-18
pubmed: 15767367
Sci Rep. 2018 Nov 26;8(1):17385
pubmed: 30478418
J Mol Biol. 1981 Aug 25;150(4):467-86
pubmed: 6276557
Front Cell Infect Microbiol. 2023 May 29;13:1187193
pubmed: 37313341
Viruses. 2016 May 23;8(5):
pubmed: 27223301
Nature. 1988 Sep 8;335(6186):176-8
pubmed: 3412473
Sci Immunol. 2022 Jul 22;7(73):eabl4102
pubmed: 35867800
Commun Biol. 2020 Nov 3;3(1):643
pubmed: 33144673
Pharmaceuticals (Basel). 2022 Mar 15;15(3):
pubmed: 35337151
J Virol. 2017 Jun 9;91(13):
pubmed: 28424281
Lancet Microbe. 2022 Apr;3(4):e252-e264
pubmed: 35287430
Vaccine. 2017 Feb 7;35(6):929-937
pubmed: 28069361
NPJ Vaccines. 2023 Mar 16;8(1):41
pubmed: 36928589
J Virol. 2002 Oct;76(19):9773-86
pubmed: 12208956
Int J Infect Dis. 2004 Oct;8 Suppl 2:S31-44
pubmed: 15491873
Nat Commun. 2020 Nov 30;11(1):6121
pubmed: 33257686
Biotechniques. 2011 May;50(5):303-9
pubmed: 21548892
Nat Commun. 2023 Aug 8;14(1):4789
pubmed: 37553348
Front Immunol. 2018 Aug 02;9:1756
pubmed: 30116244
Cancer Gene Ther. 2023 Jul;30(7):1029-1039
pubmed: 37016144
J Virol. 2019 Jan 17;93(3):
pubmed: 30429343
Front Immunol. 2022 Jul 22;13:914969
pubmed: 35935987
Vaccines (Basel). 2022 Aug 17;10(8):
pubmed: 36016218
PLoS Pathog. 2020 Jun 26;16(6):e1008522
pubmed: 32589686
J Virol Methods. 2015 Mar;213:18-25
pubmed: 25479355
Hum Vaccin Immunother. 2013 Jan;9(1):50-62
pubmed: 23143773
J Virol. 2018 Mar 28;92(8):
pubmed: 29437967
Biomedicines. 2020 Nov 26;8(12):
pubmed: 33256205
Curr Opin Immunol. 2021 Aug;71:27-33
pubmed: 33873076
Vaccines (Basel). 2023 May 21;11(5):
pubmed: 37243110
Zentralbl Bakteriol B. 1978 Dec;167(5-6):375-90
pubmed: 219640
Front Immunol. 2021 Sep 17;12:747866
pubmed: 34603336
PLoS One. 2011;6(8):e24244
pubmed: 21909386
Vaccine. 2011 Jan 10;29(3):501-11
pubmed: 21055490
Virology. 1990 Nov;179(1):276-86
pubmed: 2171207
J Gen Virol. 2011 Oct;92(Pt 10):2405-2410
pubmed: 21715598
J Virol. 2019 Jan 17;93(3):
pubmed: 30429340
J Virol. 2009 Oct;83(20):10627-36
pubmed: 19656868
Antiviral Res. 2018 May;153:49-59
pubmed: 29550516
Nat Neurosci. 2023 Feb;26(2):226-238
pubmed: 36624276
J Infect Dis. 2023 Apr 20;:
pubmed: 37079393
Dev Biol Stand. 1994;82:65-9
pubmed: 7958484
Appl Microbiol Biotechnol. 2017 Oct;101(20):7435-7443
pubmed: 28887634
PLoS Pathog. 2014 May 01;10(5):e1004090
pubmed: 24788700
PLoS Pathog. 2019 Feb 28;15(2):e1007564
pubmed: 30817809
J Virol. 1996 Sep;70(9):6479-85
pubmed: 8709286
Front Immunol. 2019 Dec 04;10:2793
pubmed: 31867001
JAMA. 2009 Mar 11;301(10):1025-33
pubmed: 19278946
PLoS One. 2010 Aug 24;5(8):e12395
pubmed: 20811493
Cell. 1995 May 19;81(4):551-60
pubmed: 7758109
Sci Rep. 2023 Jul 14;13(1):11384
pubmed: 37452062
Hum Vaccin Immunother. 2012 Jul;8(7):961-70
pubmed: 22777090
Front Immunol. 2023 Jun 19;14:1160065
pubmed: 37404819
J Virol. 2012 Sep;86(17):9514-9
pubmed: 22740406
J Virol. 1990 Jun;64(6):3108-11
pubmed: 2159565
NPJ Vaccines. 2023 Feb 15;8(1):19
pubmed: 36792640
NPJ Vaccines. 2020 Jun 2;5(1):44
pubmed: 32550013
Vaccine. 2004 Sep 3;22(25-26):3358-66
pubmed: 15308360
Annu Rev Microbiol. 1994;48:345-69
pubmed: 7826010
Virol J. 2010 Mar 15;7:59
pubmed: 20230632
J Virol. 2006 Aug;80(15):7714-28
pubmed: 16840350
Vaccine. 2019 May 31;37(25):3335-3342
pubmed: 31076161