Comparison of halitosis according to herbal mouthwash containing Glycyrrhiza uralensis extract and saline mouthwash: A randomized, double-blind, placebo-controlled study.

Glycyrrhiza uralensis extract halitosis halitosis-causing oral bacteria mouthwash randomized controlled trial

Journal

International journal of dental hygiene

ISSN: 1601-5037

Titre abrégé: Int J Dent Hyg

Pays: England

ID NLM: 101168070

Informations de publication

Date de publication:
28 Aug 2023

Historique:

revised: 03 08 2023

received: 27 12 2022

accepted: 06 08 2023

medline: 28 8 2023

pubmed: 28 8 2023

entrez: 28 8 2023

Statut: aheadofprint

Résumé

This study was conducted in order to determine the effect on halitosis and the antibacterial effect against halitosis-causing bacteria of the mouthwash made of the natural material, Glycyrrhiza uralensis (G. uralensis) extract. A randomized, double-blind, placebo-controlled study was conducted on 60 patients who visited M dental clinic located in Busan, South Korea, excluding those with systemic disease that may induce halitosis. There were 30 patients classified to the saline gargle group and the remaining 30 patients were classified to the G. uralensis extract gargle group. In addition, their level of halitosis and halitosis-causing bacteria were measured. They visited the dental clinic on a fasted state at baseline before gargle application (Baseline), immediately after gargle application (Treatment) and 5 days after gargle application (After 5 Days). For clinical indicators, participants were tested for halitosis and bacteria immediately after waking up without brushing their teeth and without hydration. The prevalence of halitosis decreased in the G. uralensis extract gargle group compared to the saline gargle group at Treatment and After 5 Days. In cases with pseudo halitosis, there was a significant decrease in halitosis-causing bacteria when G. uralensis extract gargle was applied (p < 0.05). It was identified that using a mouthwash made with G. uralensis extract is effective for halitosis improvement and reduction of halitosis-causing bacteria. Therefore, using a mouthwash containing G. uralensis extract, it will be effective in improving bad breath and oral hygiene will be possible.

Identifiants

DOI: 10.1111/idh.12724 PMID: 37635655

pubmed: 37635655

doi: 10.1111/idh.12724

doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

Subventions

Organisme : This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT)

ID : 2020R1C1C1005306

Informations de copyright

Références

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