Prevalence and Auditory Characteristics of Auditory Neuropathy Spectrum Disorder in Adult Population with Sensory Neural Hearing Loss: A Hospital Based Study in South India.
Auditory brainstem response
Auditory neuropathy spectrum disorder
Cochlear microphonics
Otoacoustic emission
Sensory neural hearing loss
Journal
Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
ISSN: 2231-3796
Titre abrégé: Indian J Otolaryngol Head Neck Surg
Pays: India
ID NLM: 9422551
Informations de publication
Date de publication:
Sep 2023
Sep 2023
Historique:
received:
03
07
2022
accepted:
31
03
2023
pmc-release:
01
09
2024
medline:
28
8
2023
pubmed:
28
8
2023
entrez:
28
8
2023
Statut:
ppublish
Résumé
Auditory neuropathy spectrum disorder (ANSD) is a heterogenous group of disorder characterized by abnormalities in auditory brainstem responses (ABR) with preserved otoacoustic emissions and/or cochlear microphonics. The aim of the study is to estimate the prevalence and evaluate the audiological characteristics of ANSD in adult population with sensory neural hearing loss. A prospective study was conducted on the adult population (≥ 18 years) attending ENT outpatients clinic at Rajiv Gandhi Government General Hospital, Chennai. All patients reported to the department with auditory and vestibular symptoms underwent case history, otoscopic examination, and routine audiological evaluation (pure tone audiometry, speech audiometry and immittance audiometry). Patients with indications of ANSD in case history and routine audiological evaluation were further evaluated using distortion product otoacoustic emissions and ABR. A total of 8682 adult population was evaluated during the period of 2017 to 2018. Out of 8682 patients, 1343 (15.46%) of them had sensory neural hearing loss of varying degrees. Out of 1343 adults with sensory neural hearing loss, 24 (1.78%) adults were diagnosed as ANSD. The prevalence of ANSD in adult population with sensory neural hearing loss in our study is 1.32% per 1000 adults. The clinical characteristics of ANSD shows impairment in speech perception irrespective of degree of hearing loss, preserved cochlear functions and abnormal ABR. Hence ANSD is not a rare clinical finding in adults with sensory neural hearing loss, but its prevalence was estimated to be lower in Indian population. Often young females are affected causing significant impairment in speech perception and disability.
Identifiants
pubmed: 37636754
doi: 10.1007/s12070-023-03766-6
pii: 3766
pmc: PMC10447738
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1906-1911Informations de copyright
© Association of Otolaryngologists of India 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
Déclaration de conflit d'intérêts
Conflict of InterestResearch involves Human Participants. Authors declare that there is no conflict of interest in this study.
Références
J Neurophysiol. 2005 Jun;93(6):3050-63
pubmed: 15615831
Ann Indian Acad Neurol. 2015 Apr-Jun;18(2):171-80
pubmed: 26019414
Indian J Otolaryngol Head Neck Surg. 2016 Jun;68(2):196-201
pubmed: 27340636
Int J Audiol. 2006 Jun;45(6):360-6
pubmed: 16777783
Int J Pediatr Otorhinolaryngol. 2011 Feb;75(2):151-8
pubmed: 21176974
Pediatrics. 2005 Oct;116(4):933-8
pubmed: 16199704
J Assoc Res Otolaryngol. 2000 Aug;1(1):33-45
pubmed: 11548236
Int J Pediatr Otorhinolaryngol. 2006 Aug;70(8):1415-22
pubmed: 16574250
J Am Acad Audiol. 2003 Aug;14(6):302-13
pubmed: 14552424
Acta Neurol Scand. 2003 Aug;108(2):130-5
pubmed: 12859291
J Perinatol. 2007 Nov;27(11):718-23
pubmed: 17703185
Int J Pediatr Otorhinolaryngol. 2009 Jul;73(7):937-9
pubmed: 19409623
J Clin Med. 2020 Apr 10;9(4):
pubmed: 32290039
Neuroreport. 1999 Nov 8;10(16):3429-35
pubmed: 10599857
Trends Amplif. 2005;9(1):1-43
pubmed: 15920648
Ear Hear. 2004 Feb;25(1):34-46
pubmed: 14770016
Brain. 2015 Nov;138(Pt 11):3141-58
pubmed: 26463676
Eur J Pediatr. 2016 Jul;175(7):993-1000
pubmed: 27220871
Int J Pediatr Otorhinolaryngol. 2012 Sep;76(9):1351-4
pubmed: 22795739
Ear Hear. 2002 Jun;23(3):239-53
pubmed: 12072616
Brain. 1996 Jun;119 ( Pt 3):741-53
pubmed: 8673487
Ear Hear. 1999 Jun;20(3):238-52
pubmed: 10386850
Int J Audiol. 2010 Jan;49(1):30-43
pubmed: 20053155
J Basic Clin Physiol Pharmacol. 2000;11(3):215-30
pubmed: 11041385
Braz J Otorhinolaryngol. 2013 Aug;79(4):429-33
pubmed: 23929141
Int J Pediatr Otorhinolaryngol. 2012 Nov;76(11):1668-70
pubmed: 22939890