Infection-induced seroconversion and seroprevalence of SARS-CoV-2 among a cohort of children and youth in Montreal, Canada.
Canada
SARS‐CoV‐2
adolescents
children
seroconversion
seroprevalence
Journal
Influenza and other respiratory viruses
ISSN: 1750-2659
Titre abrégé: Influenza Other Respir Viruses
Pays: England
ID NLM: 101304007
Informations de publication
Date de publication:
08 2023
08 2023
Historique:
received:
19
05
2023
revised:
02
08
2023
accepted:
07
08
2023
medline:
29
8
2023
pubmed:
28
8
2023
entrez:
28
8
2023
Statut:
epublish
Résumé
The EnCORE study is a prospective serology study of SARS-CoV-2 in a cohort of children from Montreal, Canada. Based on data from our fourth round of data collection (May-October 2022), we estimated SARS-CoV-2 seroprevalence and seroconversion. Using multivariable regression, we identified factors associated with seroconversion. Our results show that previously seronegative children were approximately 9-12 times more likely to seroconvert during the early Omicron-dominant period compared to pre-Omicron rounds. Unlike the pre-Omicron rounds, the adjusted rate of seroconversion among 2- to 4-year-olds was higher than older age groups. As seen previously, higher seroconversion rates were associated with ethnic/racial minority status.
Identifiants
pubmed: 37638094
doi: 10.1111/irv.13186
pii: IRV13186
pmc: PMC10457549
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e13186Informations de copyright
© 2023 The Authors. Influenza and Other Respiratory Viruses published by John Wiley & Sons Ltd.
Déclaration de conflit d'intérêts
JP reports grants from MedImmune, grants and personal fees from Merck and AbbVie, and personal fees from AstraZeneca, all outside the submitted work.
Références
Emerg Infect Dis. 2022 Nov;28(11):2270-2280
pubmed: 36285986
BMJ Open. 2021 Jul 8;11(7):e053245
pubmed: 34244288
MMWR Morb Mortal Wkly Rep. 2022 Apr 29;71(17):606-608
pubmed: 35482574
JAMA Netw Open. 2021 Nov 1;4(11):e2134147
pubmed: 34762110
Int J Infect Dis. 2023 Jun;131:119-126
pubmed: 36963656
JAMA Netw Open. 2021 Nov 1;4(11):e2135975
pubmed: 34812845
Signal Transduct Target Ther. 2022 May 7;7(1):151
pubmed: 35525870
JAMA Pediatr. 2022 Aug 1;176(8):811-813
pubmed: 35363246
Pediatrics. 2023 Apr 1;151(4):
pubmed: 36866446
Influenza Other Respir Viruses. 2023 Aug 25;17(8):e13186
pubmed: 37638094
Nat Commun. 2022 Jan 10;13(1):128
pubmed: 35013206