Is Head and Neck Free Flap Reconstruction Feasible in Jehovah's Witness Patients?


Journal

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
ISSN: 1531-5053
Titre abrégé: J Oral Maxillofac Surg
Pays: United States
ID NLM: 8206428

Informations de publication

Date de publication:
11 2023
Historique:
received: 14 01 2023
revised: 07 08 2023
accepted: 08 08 2023
medline: 6 11 2023
pubmed: 29 8 2023
entrez: 28 8 2023
Statut: ppublish

Résumé

Jehovah's Witnesses (JW) population are members of a religious group that refuses blood transfusion. This presents a dilemma for surgical teams when performing major surgical procedures on these patients. This study aimed to assess the safety and feasibility of undergoing microvascular free flaps for maxillofacial reconstruction in JW patients and whether the type of underlying pathology impacts outcomes. This was a multi-institutional retrospective cohort study. The sample consisted of all JW patients who have undergone microvascular free tissue transfer for maxillofacial pathology between January 2016 and January 2021. The primary predictor variable was the underlying pathology for which patients underwent head and neck free flap reconstruction; this was benign versus malignant disease. The primary outcome variables were safety, defined as discharge from the hospital with no mortality, and feasibility defined as successful free flap reconstruction. Other variables included age, race, sex, length of surgery, length of hospital stay, and intraoperative use of vasopressors. Data analysis was performed utilizing t-tests for means and χ A total of 12 participants from 7 participating sites met the inclusion criteria. There were 9 males and 3 females with a mean age of 58.3 ± 8.3 years. There were no deaths in this cohort and all patients were discharged from the hospital. All 12 free flap reconstructions were successful with no incidents of free flap loss; none of the patients received any blood transfusions or any other blood products. Subgroup analysis showed that patients treated for malignant disease versus benign disease had longer operations (11.2 ± 2.9 vs 6.3 ± 0.2 hours, P < .01) and a longer hospital length of stay (11.8 ± 4.9 vs 5.3 ± 0.5 days, P = .04). Our series supports the safety and feasibility of maxillofacial free flap reconstruction in this challenging subset of patients. Microvascular reconstructive surgeries for malignant diseases often result in longer operative times and hospital stays.

Sections du résumé

BACKGROUND
Jehovah's Witnesses (JW) population are members of a religious group that refuses blood transfusion. This presents a dilemma for surgical teams when performing major surgical procedures on these patients.
PURPOSE
This study aimed to assess the safety and feasibility of undergoing microvascular free flaps for maxillofacial reconstruction in JW patients and whether the type of underlying pathology impacts outcomes.
STUDY DESIGN, SETTING, AND SAMPLE
This was a multi-institutional retrospective cohort study. The sample consisted of all JW patients who have undergone microvascular free tissue transfer for maxillofacial pathology between January 2016 and January 2021.
PREDICTOR VARIABLE
The primary predictor variable was the underlying pathology for which patients underwent head and neck free flap reconstruction; this was benign versus malignant disease.
MAIN OUTCOME VARIABLES
The primary outcome variables were safety, defined as discharge from the hospital with no mortality, and feasibility defined as successful free flap reconstruction.
COVARIATES
Other variables included age, race, sex, length of surgery, length of hospital stay, and intraoperative use of vasopressors.
ANALYSIS
Data analysis was performed utilizing t-tests for means and χ
RESULTS
A total of 12 participants from 7 participating sites met the inclusion criteria. There were 9 males and 3 females with a mean age of 58.3 ± 8.3 years. There were no deaths in this cohort and all patients were discharged from the hospital. All 12 free flap reconstructions were successful with no incidents of free flap loss; none of the patients received any blood transfusions or any other blood products. Subgroup analysis showed that patients treated for malignant disease versus benign disease had longer operations (11.2 ± 2.9 vs 6.3 ± 0.2 hours, P < .01) and a longer hospital length of stay (11.8 ± 4.9 vs 5.3 ± 0.5 days, P = .04).
CONCLUSION AND RELEVANCE
Our series supports the safety and feasibility of maxillofacial free flap reconstruction in this challenging subset of patients. Microvascular reconstructive surgeries for malignant diseases often result in longer operative times and hospital stays.

Identifiants

pubmed: 37640237
pii: S0278-2391(23)00802-9
doi: 10.1016/j.joms.2023.08.006
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1435-1442

Informations de copyright

Copyright © 2023 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

Auteurs

Mohammed Qaisi (M)

Professor, Oral & Maxillofacial Surgery (MWU), Program Director, Division of Oral & Maxillofacial Surgery, Adjunct Attending Physician, Division of Otolaryngology, Cook County Health, Chicago, IL. Electronic address: mqaisi@yahoo.com.

Thaer Al Azzawi (T)

Research Fellow, Division of Oral and Maxillofacial Surgery, Cook County Health, Chicago, IL.

James Murphy (J)

Associate Professor, Oral & Maxillofacial Surgery (MWU), Division of Oral and Maxillofacial Surgery, Cook County Health, Chicago, IL.

Joshua Lubek (J)

Professor, Oral & Maxillofacial Surgery, Fellowship Director, Oral-Head & Neck Oncology/Microvascular Surgery Fellowship, University of Maryland Medical Center, Baltimore, MD.

Waleed Zaid (W)

Associate Professor, Department of Oral and Maxillofacial Surgery, Louisiana State University Health Sciences Center, Chief of Oral & Maxillofacial Surgery, Our Lady of the Lake Regional Medical Center, Baton Rouge, LA.

Ramzey Tursun (R)

Fellowship Director, Oral, Head, & Neck Oncologic and Microvascular Reconstructive Surgery, Associate Professor of Clinical Surgery, Jackson Memorial Hospital, Miami, FL.

Arshad Kaleem (A)

Assistant Professor, Oral & Maxillofacial Surgery, Jackson Memorial Hospital, Miami, FL.

Ketan Patel (K)

Attending Surgeon, Division of Oral and Maxillofacial Surgery, North Memorial Health Hospital, Robbinsdale, MN.

Michael R Markiewicz (MR)

Associate Dean for Hospital Affairs, Professor and Chair, Department of Oral & Maxillofacial Surgery, University of Buffalo School of Dental Medicine, Buffalo, NY.

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