Nicotinamide mononucleotide inhibits oxidative stress-induced damage in a SIRT1/NQO-1-dependent manner.
HUVEC
NQO1
Nicotinamide mononucleotide
Oxidative stress
Senescence
Sirtuin
Journal
Toxicology in vitro : an international journal published in association with BIBRA
ISSN: 1879-3177
Titre abrégé: Toxicol In Vitro
Pays: England
ID NLM: 8712158
Informations de publication
Date de publication:
Dec 2023
Dec 2023
Historique:
received:
02
05
2023
revised:
23
08
2023
accepted:
25
08
2023
medline:
23
10
2023
pubmed:
29
8
2023
entrez:
28
8
2023
Statut:
ppublish
Résumé
Oxidative stress causes endothelial dysfunction, which is associated with vascular cellular aging and is causally related to cardiovascular disease pathogenesis. Preclinical studies indicate that a nicotinamide adenine dinucleotide (NAD
Identifiants
pubmed: 37640247
pii: S0887-2333(23)00132-7
doi: 10.1016/j.tiv.2023.105683
pii:
doi:
Substances chimiques
Actins
0
Hydrogen Peroxide
BBX060AN9V
NAD
0U46U6E8UK
Nicotinamide Mononucleotide
1094-61-7
SIRT1 protein, human
EC 3.5.1.-
Sirtuin 1
EC 3.5.1.-
NQO1 protein, human
EC 1.6.5.2
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
105683Informations de copyright
Copyright © 2023 Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.