Osteoarticular infection caused by Talaromyces Marneffei and Salmonella in a person living with HIV: a case report.
Case report
HIV
NGS
Salmonella
Talaromyces marneffei
Journal
BMC infectious diseases
ISSN: 1471-2334
Titre abrégé: BMC Infect Dis
Pays: England
ID NLM: 100968551
Informations de publication
Date de publication:
28 Aug 2023
28 Aug 2023
Historique:
received:
16
02
2023
accepted:
22
08
2023
medline:
31
8
2023
pubmed:
29
8
2023
entrez:
28
8
2023
Statut:
epublish
Résumé
Talaromycosis is a common invasive fungal disease in patients with HIV. However, its association with bone destruction is unusual in AIDS patients with talaromycosis. This report covers the case of a 38-year-old male AIDS patient coinfected with Talaromyces marneffei and Salmonella. The case, which involved bone destruction, was identified via metagenomic next-generation sequencing (mNGS). Following treatment with a combination of amphotericin B and piperacillin-tazobactam, the patient's elbow motion noticeably improved. Imaging findings revealed that the progression of bony destruction had halted. Bone damage due to Talaromyces marneffei infection is infrequent in HIV-positive patients. Therefore, healthcare professionals must be vigilant for potential bone lesions associated with this type of infection. Prompt diagnosis and antimicrobial treatment are crucial.
Identifiants
pubmed: 37641024
doi: 10.1186/s12879-023-08554-9
pii: 10.1186/s12879-023-08554-9
pmc: PMC10463968
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
560Subventions
Organisme : Zhejiang TCM Science and Technology Program of China
ID : 2022ZB292
Informations de copyright
© 2023. BioMed Central Ltd., part of Springer Nature.
Références
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