Chemerin triggers migration of a CD8 T cell subset with natural killer cell functions.

CMKLR1 T cell trafficking chemerin chemoattractant immune oncology integrin

Journal

Molecular therapy : the journal of the American Society of Gene Therapy
ISSN: 1525-0024
Titre abrégé: Mol Ther
Pays: United States
ID NLM: 100890581

Informations de publication

Date de publication:
04 Oct 2023
Historique:
received: 05 04 2023
revised: 31 07 2023
accepted: 25 08 2023
pmc-release: 04 10 2024
pubmed: 29 8 2023
medline: 29 8 2023
entrez: 29 8 2023
Statut: ppublish

Résumé

The recruitment of cells with effector functions into the tumor microenvironment holds potential for delaying cancer progression. We show that subsets of human CD28-effector CD8 T cells, CCR7

Identifiants

pubmed: 37641406
pii: S1525-0016(23)00447-1
doi: 10.1016/j.ymthe.2023.08.015
pmc: PMC10556222
mid: NIHMS1932080
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2887-2900

Subventions

Organisme : BLRD VA
ID : I01 BX004115
Pays : United States

Informations de copyright

Published by Elsevier Inc.

Déclaration de conflit d'intérêts

Declaration of interests The authors declare no competing interests.

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Auteurs

Romain Ballet (R)

Palo Alto Veterans Institute for Research (PAVIR), Veterans Affairs Palo Alto Health Care System (VAPAHCS), Palo Alto, CA 94304, USA; Laboratory of Immunology and Vascular Biology, Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.

Melissa LaJevic (M)

Palo Alto Veterans Institute for Research (PAVIR), Veterans Affairs Palo Alto Health Care System (VAPAHCS), Palo Alto, CA 94304, USA; Laboratory of Immunology and Vascular Biology, Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.

Noelle Huskey-Mullin (N)

Pfizer Centers for Therapeutic Innovation, La Jolla, CA 92121, USA.

Rachel Roach (R)

Pfizer Centers for Therapeutic Innovation, La Jolla, CA 92121, USA.

Kevin Brulois (K)

Palo Alto Veterans Institute for Research (PAVIR), Veterans Affairs Palo Alto Health Care System (VAPAHCS), Palo Alto, CA 94304, USA; Laboratory of Immunology and Vascular Biology, Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.

Ying Huang (Y)

Pfizer Centers for Therapeutic Innovation, La Jolla, CA 92121, USA.

Muhammad A Saeed (MA)

Department of Medicine, Washington University School of Medicine, St Louis, MO 63130, USA.

Ha X Dang (HX)

Department of Medicine, Washington University School of Medicine, St Louis, MO 63130, USA.

Russell K Pachynski (RK)

Department of Medicine, Washington University School of Medicine, St Louis, MO 63130, USA.

Elizabeth Wilson (E)

Pfizer Centers for Therapeutic Innovation, La Jolla, CA 92121, USA.

Eugene C Butcher (EC)

Laboratory of Immunology and Vascular Biology, Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.

Brian A Zabel (BA)

Palo Alto Veterans Institute for Research (PAVIR), Veterans Affairs Palo Alto Health Care System (VAPAHCS), Palo Alto, CA 94304, USA; Laboratory of Immunology and Vascular Biology, Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: bazabel@stanford.edu.

Classifications MeSH