Long-term outcomes of pars plana Ahmed valve implant and vitrectomy in eyes with refractory glaucoma.

anti-glaucoma agent glaucoma drainage implant intraocular pressure neovascular glaucoma pars plana

Journal

Medical hypothesis, discovery & innovation ophthalmology journal
ISSN: 2322-3219
Titre abrégé: Med Hypothesis Discov Innov Ophthalmol
Pays: United States
ID NLM: 101611331

Informations de publication

Date de publication:
2022
Historique:
received: 02 04 2022
accepted: 30 04 2022
medline: 30 4 2022
pubmed: 30 4 2022
entrez: 29 8 2023
Statut: epublish

Résumé

Pars plana vitrectomy with implantation of an Ahmed glaucoma valve in the vitreous cavity has been reported with a success rate in the management of refractory and neovascular glaucoma. This study aimed to present the outcomes of pars plana Ahmed glaucoma valve (PPAV) surgical implantation in cases with refractory glaucoma. In this single-center, retrospective, comparative study, 87 consecutive patients diagnosed with refractory glaucoma who underwent PPAV surgical implantation between October 2015 and October 2019 were evaluated. A successful postoperative outcome was defined as intraocular pressure (IOP) ≤ 21 mmHg upon examination and a reduction in the number of anti-glaucoma agents used at the latest follow-up. Finally, 81 eyes of 78 patients with refractory glaucoma were included; 54 (66.66%) of the eyes had neovascular glaucoma. The mean follow-up was 20.65 ± 12.17 months (range: 2-52 months). The mean preoperative IOP was 40.01 ± 1.19 mmHg and reduced significantly to 16.73 ± 0.82 mmHg at the latest follow-up ( PPAV surgery is a successful procedure for IOP reduction in patients with refractory glaucoma. Our study demonstrated either reduction or elimination of IOP lowering eye drops postoperatively. Large scale studies with a comparison group, a longer follow-up, and having various subtypes of glaucoma are required as future research to confirm these outcomes.

Sections du résumé

Background UNASSIGNED
Pars plana vitrectomy with implantation of an Ahmed glaucoma valve in the vitreous cavity has been reported with a success rate in the management of refractory and neovascular glaucoma. This study aimed to present the outcomes of pars plana Ahmed glaucoma valve (PPAV) surgical implantation in cases with refractory glaucoma.
Methods UNASSIGNED
In this single-center, retrospective, comparative study, 87 consecutive patients diagnosed with refractory glaucoma who underwent PPAV surgical implantation between October 2015 and October 2019 were evaluated. A successful postoperative outcome was defined as intraocular pressure (IOP) ≤ 21 mmHg upon examination and a reduction in the number of anti-glaucoma agents used at the latest follow-up.
Results UNASSIGNED
Finally, 81 eyes of 78 patients with refractory glaucoma were included; 54 (66.66%) of the eyes had neovascular glaucoma. The mean follow-up was 20.65 ± 12.17 months (range: 2-52 months). The mean preoperative IOP was 40.01 ± 1.19 mmHg and reduced significantly to 16.73 ± 0.82 mmHg at the latest follow-up (
Conclusions UNASSIGNED
PPAV surgery is a successful procedure for IOP reduction in patients with refractory glaucoma. Our study demonstrated either reduction or elimination of IOP lowering eye drops postoperatively. Large scale studies with a comparison group, a longer follow-up, and having various subtypes of glaucoma are required as future research to confirm these outcomes.

Identifiants

pubmed: 37641700
doi: 10.51329/mehdiophthal1445
pmc: PMC10445320
doi:

Types de publication

Journal Article

Langues

eng

Pagination

44-51

Informations de copyright

© Author(s).

Déclaration de conflit d'intérêts

None.

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Auteurs

Sareta K Dubay (SK)

Trinidad Eye Hospital (Caribbean Vitreous and Retina Surgery Ltd), Trinidad.

Dorian Dwarika (D)

Trinidad Eye Hospital (Caribbean Vitreous and Retina Surgery Ltd), Trinidad.

Ronnie Bhola (R)

Trinidad Eye Hospital (Caribbean Vitreous and Retina Surgery Ltd), Trinidad.

Balakrishna Vineeth Kumar (BV)

Trinidad Eye Hospital (Caribbean Vitreous and Retina Surgery Ltd), Trinidad.

Classifications MeSH