Fully automated computational measurement of noise in positron emission tomography.

Algorithms Dose reduction Image enhancement Noise Positron emission tomography

Journal

European radiology
ISSN: 1432-1084
Titre abrégé: Eur Radiol
Pays: Germany
ID NLM: 9114774

Informations de publication

Date de publication:
30 Aug 2023
Historique:
received: 09 12 2022
accepted: 15 05 2023
revised: 15 04 2023
medline: 30 8 2023
pubmed: 30 8 2023
entrez: 29 8 2023
Statut: aheadofprint

Résumé

To introduce an automated computational algorithm that estimates the global noise level across the whole imaging volume of PET datasets. [ Irrespective of the absolute noise values, there was no significant difference between the GNI and manual liver measurements in terms of the distribution of noise values (p = 0.84 for Q.Clear 450, and p = 0.51 for Q.Clear 600). The GNI showed a fair to moderately strong correlation with manual noise measurements in liver parenchyma (r = 0.6 in Q.Clear 450, r = 0.54 in Q.Clear 600, all p < 0.001), and a fair correlation with manual noise measurements in lung parenchyma (r = 0.52 in Q.Clear 450, r = 0.33 in Q.Clear 600, all p < 0.001). Classification performance of the GNI for subjective image quality was AUC 0.898 for Q.Clear 450 and 0.919 for Q.Clear 600. An algorithm provides an accurate and meaningful estimation of the global noise level encountered in clinical PET imaging datasets. An automated computational approach that measures the global noise level of PET imaging datasets may facilitate quality standardization and benchmarking of clinical PET imaging within and across institutions. • Noise is an important quantitative marker that strongly impacts image quality of PET images. • An automated computational noise measurement algorithm provides an accurate and meaningful estimation of the global noise level encountered in clinical PET imaging datasets. • An automated computational approach that measures the global noise level of PET imaging datasets may facilitate quality standardization and benchmarking as well as protocol harmonization.

Identifiants

pubmed: 37644149
doi: 10.1007/s00330-023-10056-w
pii: 10.1007/s00330-023-10056-w
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2023. The Author(s).

Références

Hess S, Blomberg BA, Zhu HJ et al (2014) The pivotal role of FDG-PET/CT in modern medicine. Acad Radiol 21:232–249. https://doi.org/10.1016/j.acra.2013.11.002
doi: 10.1016/j.acra.2013.11.002 pubmed: 24439337
Zeimpekis KG, Kotasidis FA, Huellner M et al (2022) NEMA NU 2–2018 performance evaluation of a new generation 30-cm axial field-of-view Discovery MI PET/CT. Eur J Nucl Med Mol Imaging 49:3023–3032. https://doi.org/10.1007/s00259-022-05751-7
doi: 10.1007/s00259-022-05751-7 pubmed: 35284970 pmcid: 9250480
van der Vos CS, Koopman D, Rijnsdorp S et al (2017) Quantification, improvement, and harmonization of small lesion detection with state-of-the-art PET. Eur J Nucl Med Mol Imaging 44:4–16. https://doi.org/10.1007/s00259-017-3727-z
doi: 10.1007/s00259-017-3727-z pubmed: 28687866 pmcid: 5541089
Tong S, Alessio AM, Kinahan PE (2010) Noise and signal properties in PSF-based fully 3D PET image reconstruction: an experimental evaluation. Phys Med Biol 55:1453–1473. https://doi.org/10.1088/0031-9155/55/5/013
doi: 10.1088/0031-9155/55/5/013 pubmed: 20150683 pmcid: 2890317
Karakatsanis NA, Fokou E, Tsoumpas C (2015) Dosage optimization in positron emission tomography: state-of-the-art methods and future prospects. Am J Nucl Med Mol Imaging 5:527–547
pubmed: 26550543 pmcid: 4620179
Messerli M, Stolzmann P, Egger-Sigg M et al (2018) Impact of a Bayesian penalized likelihood reconstruction algorithm on image quality in novel digital PET/CT: clinical implications for the assessment of lung tumors. EJNMMI Phys 5:27. https://doi.org/10.1186/s40658-018-0223-x
doi: 10.1186/s40658-018-0223-x pubmed: 30255439 pmcid: 6156690
Mehranian A, Wollenweber SD, Walker MD et al (2022) Deep learning-based time-of-flight (ToF) image enhancement of non-ToF PET scans. Eur J Nucl Med Mol Imaging 49:3740–3749
doi: 10.1007/s00259-022-05824-7 pubmed: 35507059 pmcid: 9399038
Zhang Y, Hu P, He Y et al (2022) Ultrafast 30-s total-body PET/CT scan: a preliminary study. Eur J Nucl Med Mol Imaging 49:2504–2513. https://doi.org/10.1007/s00259-022-05838-1
doi: 10.1007/s00259-022-05838-1 pubmed: 35578037
Weyts K, Lasnon C, Ciappuccini R et al (2022) Artificial intelligence-based PET denoising could allow a two-fold reduction in [(18)F]FDG PET acquisition time in digital PET/CT. Eur J Nucl Med Mol Imaging 49:3750–3760
doi: 10.1007/s00259-022-05800-1 pubmed: 35593925 pmcid: 9399218
Xing Y, Qiao W, Wang T et al (2022) Deep learning-assisted PET imaging achieves fast scan/low-dose examination. EJNMMI Phys 9:7. https://doi.org/10.1186/s40658-022-00431-9
doi: 10.1186/s40658-022-00431-9 pubmed: 35122172 pmcid: 8816983
Wang Y-R, Baratto L, Hawk KE et al (2021) Artificial intelligence enables whole-body positron emission tomography scans with minimal radiation exposure. Eur J Nucl Med Mol Imaging 48:2771–2781. https://doi.org/10.1007/s00259-021-05197-3
doi: 10.1007/s00259-021-05197-3 pubmed: 33527176 pmcid: 8266729
Sartoretti T, Racine D, Mergen V et al (2022) Quantum iterative reconstruction for low-dose ultra-high-resolution photon-counting detector CT of the lung. Diagnostics 12:522. https://doi.org/10.3390/diagnostics12020522
doi: 10.3390/diagnostics12020522 pubmed: 35204611 pmcid: 8871296
Sartoretti T, Landsmann A, Nakhostin D et al (2022) Quantum iterative reconstruction for abdominal photon-counting detector CT improves image quality. Radiology 303:339–348. https://doi.org/10.1148/radiol.211931
doi: 10.1148/radiol.211931 pubmed: 35103540
Jungblut L, Sartoretti T, Kronenberg D, et al (2022) Performance of virtual non-contrast images generated on clinical photon-counting detector CT for emphysema quantification: proof of concept. Br J Radiol 95:20211367. https://doi.org/10.1259/bjr.20211367
Christianson O, Winslow J, Frush DP, Samei E (2015) Automated technique to measure noise in clinical CT examinations. AJR Am J Roentgenol 205:W93–W99. https://doi.org/10.2214/AJR.14.13613
doi: 10.2214/AJR.14.13613 pubmed: 26102424
(2021) R: A language and environment for statistical computing. Vienna, Austria. Version 4.1.1, https://www.r-project.org
Akoglu H (2018) User’s guide to correlation coefficients. Turk J Emerg Med 18:91–93. https://doi.org/10.1016/j.tjem.2018.08.001
doi: 10.1016/j.tjem.2018.08.001 pubmed: 30191186 pmcid: 6107969
Chan YH (2003) Biostatistics 104: correlational analysis. Singapore Med J 44:614–619
pubmed: 14770254
Hu P, Zhang Y, Yu H et al (2021) Total-body 18F-FDG PET/CT scan in oncology patients: how fast could it be? Eur J Nucl Med Mol Imaging 48:2384–2394. https://doi.org/10.1007/s00259-021-05357-5
doi: 10.1007/s00259-021-05357-5 pubmed: 33866409
Aberle DR, DeMello S, Berg CD et al (2013) Results of the two incidence screenings in the national lung screening trial. N Engl J Med 369:920–931. https://doi.org/10.1056/NEJMoa1208962
doi: 10.1056/NEJMoa1208962 pubmed: 24004119 pmcid: 4307922
Trägårdh E, Minarik D, Almquist H et al (2019) Impact of acquisition time and penalizing factor in a block-sequential regularized expectation maximization reconstruction algorithm on a Si-photomultiplier-based PET-CT system for 18F-FDG. EJNMMI Res 9:64. https://doi.org/10.1186/s13550-019-0535-4
doi: 10.1186/s13550-019-0535-4 pubmed: 31342214 pmcid: 6656834
Xiao J, Yu H, Sui X et al (2021) Can the BMI-based dose regimen be used to reduce injection activity and to obtain a constant image quality in oncological patients by 18F-FDG total-body PET/CT imaging? Eur J Nucl Med Mol Imaging 49:269–278. https://doi.org/10.1007/s00259-021-05462-5
doi: 10.1007/s00259-021-05462-5 pubmed: 34185138
Sekine T, Delso G, Zeimpekis KG et al (2018) Reduction of
doi: 10.1148/radiol.2017162305 pubmed: 28914600
Yan J, Schaefferkoetter J, Conti M, Townsend D (2016) A method to assess image quality for low-dose PET: analysis of SNR, CNR, bias and image noise. Cancer Imaging 16:26. https://doi.org/10.1186/s40644-016-0086-0
doi: 10.1186/s40644-016-0086-0 pubmed: 27565136 pmcid: 5002150
Queiroz MA, Wollenweber SD, von Schulthess G et al (2014) Clinical image quality perception and its relation to NECR measurements in PET. EJNMMI Phys 1:103. https://doi.org/10.1186/s40658-014-0103-y
doi: 10.1186/s40658-014-0103-y pubmed: 26501461 pmcid: 4546067
Rana N, Kaur M, Singh H, Mittal BR (2021) Dose optimization in
doi: 10.2967/jnmt.120.250282 pubmed: 32887760

Auteurs

Thomas Sartoretti (T)

Department of Nuclear Medicine, University Hospital Zurich, Rämistrasse 100, CH-8091, Zurich, Switzerland.
University of Zurich, Zurich, Switzerland.
Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, Zurich, Switzerland.

Stephan Skawran (S)

Department of Nuclear Medicine, University Hospital Zurich, Rämistrasse 100, CH-8091, Zurich, Switzerland.
University of Zurich, Zurich, Switzerland.

Antonio G Gennari (AG)

Department of Nuclear Medicine, University Hospital Zurich, Rämistrasse 100, CH-8091, Zurich, Switzerland.
University of Zurich, Zurich, Switzerland.

Alexander Maurer (A)

Department of Nuclear Medicine, University Hospital Zurich, Rämistrasse 100, CH-8091, Zurich, Switzerland.
University of Zurich, Zurich, Switzerland.

André Euler (A)

University of Zurich, Zurich, Switzerland.
Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, Zurich, Switzerland.

Valerie Treyer (V)

Department of Nuclear Medicine, University Hospital Zurich, Rämistrasse 100, CH-8091, Zurich, Switzerland.
University of Zurich, Zurich, Switzerland.

Elisabeth Sartoretti (E)

Department of Nuclear Medicine, University Hospital Zurich, Rämistrasse 100, CH-8091, Zurich, Switzerland.
University of Zurich, Zurich, Switzerland.

Stephan Waelti (S)

Department of Nuclear Medicine, University Hospital Zurich, Rämistrasse 100, CH-8091, Zurich, Switzerland.
University of Zurich, Zurich, Switzerland.
Department of Radiology and Nuclear Medicine, Children's Hospital of Eastern Switzerland, St. Gallen, Switzerland.

Moritz Schwyzer (M)

Department of Nuclear Medicine, University Hospital Zurich, Rämistrasse 100, CH-8091, Zurich, Switzerland.
University of Zurich, Zurich, Switzerland.
Health Sciences and Technology, Institute of Food, Nutrition and Health, ETH Zurich, Zurich, Switzerland.

Gustav K von Schulthess (GK)

Department of Nuclear Medicine, University Hospital Zurich, Rämistrasse 100, CH-8091, Zurich, Switzerland.
University of Zurich, Zurich, Switzerland.

Irene A Burger (IA)

Department of Nuclear Medicine, University Hospital Zurich, Rämistrasse 100, CH-8091, Zurich, Switzerland.
University of Zurich, Zurich, Switzerland.
Department of Nuclear Medicine, Kantonsspital Baden, Baden, Switzerland.

Martin W Huellner (MW)

Department of Nuclear Medicine, University Hospital Zurich, Rämistrasse 100, CH-8091, Zurich, Switzerland.
University of Zurich, Zurich, Switzerland.

Michael Messerli (M)

Department of Nuclear Medicine, University Hospital Zurich, Rämistrasse 100, CH-8091, Zurich, Switzerland. michael.messerli@usz.ch.
University of Zurich, Zurich, Switzerland. michael.messerli@usz.ch.

Classifications MeSH