Acrolein increases the concentration of intracellular Zn
Acrolein
intracellular Zn2⁺
mitochondrial ROS
oxidative stress
respiratory epithelial cells
Journal
Toxicology and industrial health
ISSN: 1477-0393
Titre abrégé: Toxicol Ind Health
Pays: England
ID NLM: 8602702
Informations de publication
Date de publication:
Nov 2023
Nov 2023
Historique:
medline:
23
10
2023
pubmed:
30
8
2023
entrez:
30
8
2023
Statut:
ppublish
Résumé
Smoking or occupational exposure leads to low concentrations of acrolein on the surface of the airways. Acrolein is involved in the pathophysiological processes of various respiratory diseases. Reports showed that acrolein induced an increase in mitochondrial reactive oxygen species (mROS). Furthermore, exogenous H₂O₂ was found to increase intracellular Zn
Identifiants
pubmed: 37644888
doi: 10.1177/07482337231198350
doi:
Substances chimiques
Reactive Oxygen Species
0
Acrolein
7864XYD3JJ
Hydrogen Peroxide
BBX060AN9V
Zinc
J41CSQ7QDS
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
630-637Déclaration de conflit d'intérêts
Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.