Sinapine thiocyanate exhibited anti-colorectal cancer effects by inhibiting KRT6A/S100A2 axis.
KRT6A
colorectal cancer
mobility
proliferation
sinapine thiocyanate
Journal
Cancer biology & therapy
ISSN: 1555-8576
Titre abrégé: Cancer Biol Ther
Pays: United States
ID NLM: 101137842
Informations de publication
Date de publication:
31 12 2023
31 12 2023
Historique:
medline:
1
9
2023
pubmed:
30
8
2023
entrez:
30
8
2023
Statut:
ppublish
Résumé
Sinapine thiocyanate (ST), an alkaloid existed extensively in seeds of cruciferous plants, exhibits a number of pharmacological effects, including anti-inflammatory and anti-malignancy properties. However, it is still unknown what effects and molecular mechanisms ST has on colorectal cancer (CRC). In the current study, it was indicated that ST inhibited proliferation, colony formation, and apoptosis
Identifiants
pubmed: 37647260
doi: 10.1080/15384047.2023.2249170
pmc: PMC10469431
doi:
Substances chimiques
thiocyanate
O748SU14OM
Thiocyanates
0
sinapine
09211A0HHL
Keratin-6
0
S100A2 protein, human
0
Chemotactic Factors
0
S100 Proteins
0
KRT6A protein, human
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2249170Références
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