Interventions to prevent miscarriage.


Journal

Fertility and sterility
ISSN: 1556-5653
Titre abrégé: Fertil Steril
Pays: United States
ID NLM: 0372772

Informations de publication

Date de publication:
11 2023
Historique:
received: 22 08 2023
accepted: 23 08 2023
medline: 30 10 2023
pubmed: 31 8 2023
entrez: 30 8 2023
Statut: ppublish

Résumé

The physical and psychological impact of miscarriage can be devastating. There are many lifestyle and therapeutic interventions that may prevent a miscarriage. In this review, we have outlined the key areas for health optimization to prevent pregnancy loss, drawing on the most up-to-date evidence available. The 3 key areas identified are lifestyle optimization in women, lifestyle optimization in men, and therapeutic interventions. The evidence demonstrates that the treatments to consider are first-trimester progesterone administration, levothyroxine in women with subclinical hypothyroidism, and the combination of aspirin and heparin in women with antiphospholipid antibodies.

Identifiants

pubmed: 37648141
pii: S0015-0282(23)01723-5
doi: 10.1016/j.fertnstert.2023.08.955
pii:
doi:

Substances chimiques

Aspirin R16CO5Y76E
Heparin 9005-49-6
Thyroxine Q51BO43MG4

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

951-954

Informations de copyright

Crown Copyright © 2023. Published by Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests R.K.D.S. has nothing to disclose. P.M. has nothing to disclose. R.K. has nothing to disclose. E.F. has nothing to disclose. A.D. has nothing to disclose. N.W. has nothing to disclose. A.C. has nothing to disclose.

Auteurs

Rima K Dhillon-Smith (RK)

Tommy's National Centre for Miscarriage Research, Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom. Electronic address: r.k.smith@bham.ac.uk.

Pedro Melo (P)

Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, United Kingdom.

Rosinder Kaur (R)

Tommy's National Centre for Miscarriage Research, Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.

Emily Fox (E)

Tommy's National Centre for Miscarriage Research, Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.

Adam Devall (A)

Tommy's National Centre for Miscarriage Research, Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom; WHO Collaborating Centre for Global Women's Health, Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.

Natalie Woodhead (N)

Tommy's National Centre for Miscarriage Research, Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.

Arri Coomarasamy (A)

Tommy's National Centre for Miscarriage Research, Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom; WHO Collaborating Centre for Global Women's Health, Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.

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Classifications MeSH