Mediastinal liposarcoma: a case report and review of the literature.
Cardiothoracic surgery
Case report
Literature review
Mediastinal liposarcoma
Syria
Journal
Journal of medical case reports
ISSN: 1752-1947
Titre abrégé: J Med Case Rep
Pays: England
ID NLM: 101293382
Informations de publication
Date de publication:
31 Aug 2023
31 Aug 2023
Historique:
received:
12
05
2023
accepted:
07
08
2023
medline:
1
9
2023
pubmed:
31
8
2023
entrez:
30
8
2023
Statut:
epublish
Résumé
Mediastinal Liposarcoma (ML) is an exceedingly rare neoplasm, accounting for less than 1% of all liposarcomas. Surgical resection is the most effective therapeutic modality, while adjuvant radiation therapy may be recommended for unresectable tumors. This case report presents a rare case of a 52-year-old Syrian male patient with well-differentiated mediastinal liposarcoma (ML) who presented with exertional dyspnea, cough, and weight loss. Imaging studies revealed a large tumor causing extrinsic compression on the right lung, as well as compression of the heart and great vessels. CT-guided biopsy confirmed a diagnosis of well-differentiated liposarcoma, and the patient underwent surgical resection. The patient had a rapid postoperative recovery and was discharged on the fourth day post-operation, displaying an excellent postoperative status. The patient was followed up for 3 months postoperatively with no recurrence. This report highlights the significance of incorporating ML into the differential diagnosis of mediastinal masses, particularly in individuals presenting with exertional dyspnea and weight loss. Furthermore, this report provides a comprehensive review of previously reported cases of ML in the medical literature.
Sections du résumé
BACKGROUND
BACKGROUND
Mediastinal Liposarcoma (ML) is an exceedingly rare neoplasm, accounting for less than 1% of all liposarcomas. Surgical resection is the most effective therapeutic modality, while adjuvant radiation therapy may be recommended for unresectable tumors.
CASE PRESENTATION
METHODS
This case report presents a rare case of a 52-year-old Syrian male patient with well-differentiated mediastinal liposarcoma (ML) who presented with exertional dyspnea, cough, and weight loss. Imaging studies revealed a large tumor causing extrinsic compression on the right lung, as well as compression of the heart and great vessels. CT-guided biopsy confirmed a diagnosis of well-differentiated liposarcoma, and the patient underwent surgical resection. The patient had a rapid postoperative recovery and was discharged on the fourth day post-operation, displaying an excellent postoperative status. The patient was followed up for 3 months postoperatively with no recurrence.
CONCLUSION
CONCLUSIONS
This report highlights the significance of incorporating ML into the differential diagnosis of mediastinal masses, particularly in individuals presenting with exertional dyspnea and weight loss. Furthermore, this report provides a comprehensive review of previously reported cases of ML in the medical literature.
Identifiants
pubmed: 37649065
doi: 10.1186/s13256-023-04121-7
pii: 10.1186/s13256-023-04121-7
pmc: PMC10469449
doi:
Types de publication
Review
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
372Informations de copyright
© 2023. BioMed Central Ltd., part of Springer Nature.
Références
Asian Cardiovasc Thorac Ann. 2015 Nov;23(9):1121-4
pubmed: 26048590
Ann Thorac Cardiovasc Surg. 2014;20 Suppl:606-8
pubmed: 23801175
Exp Mol Pathol. 2020 Oct;116:104517
pubmed: 32791064
Radiol Cardiothorac Imaging. 2022 Mar 17;4(2):e210259
pubmed: 35506134
Medicine (Baltimore). 2018 Oct;97(42):e12873
pubmed: 30335003
Cir Cir. 2014 Mar-Apr;82(2):177-82
pubmed: 25312317
Pathologica. 2017 Dec;109(4):401-404
pubmed: 29449733
J Surg Case Rep. 2016 Jan 01;2016(1):
pubmed: 26724326
Oncol Lett. 2016 Jun;11(6):3782-3784
pubmed: 27313694
J BUON. 2008 Jul-Sep;13(3):429-31
pubmed: 18979562
Thorac Cancer. 2018 Dec;9(12):1733-1740
pubmed: 30329218
Ann R Coll Surg Engl. 2021 Sep;103(8):e255-e258
pubmed: 34464560
J Surg Case Rep. 2015 Sep 25;2015(9):
pubmed: 26410831
J Surg Case Rep. 2017 Jan 2;2017(1):
pubmed: 28044001
J Cardiothorac Surg. 2014 Jan 06;9:6
pubmed: 24393470
Ann R Coll Surg Engl. 2018 Feb;100(2):e22-e27
pubmed: 29182001
Asian Cardiovasc Thorac Ann. 2017 Jul;25(6):472-473
pubmed: 27225397
J Ayub Med Coll Abbottabad. 2016 Oct-Dec;28(4):818-820
pubmed: 28828769
Virchows Arch. 2014 Apr;464(4):489-93
pubmed: 24558031
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2012 Aug;34(4):405-8
pubmed: 22954127