Diagnosis and practical management of digoxin toxicity: a narrative review and consensus.


Journal

European journal of emergency medicine : official journal of the European Society for Emergency Medicine
ISSN: 1473-5695
Titre abrégé: Eur J Emerg Med
Pays: England
ID NLM: 9442482

Informations de publication

Date de publication:
01 Dec 2023
Historique:
medline: 30 10 2023
pubmed: 31 8 2023
entrez: 31 8 2023
Statut: ppublish

Résumé

There are currently no universally accepted guidelines for the management of digoxin toxicity. In the absence of clinical practice guidelines, a set of consensus recommendations for management of digoxin toxicity in the clinical setting were developed through a modified Delphi approach. The recommendations highlight the importance of early recognition of signs of potentially life-threatening toxicity that requires immediate treatment with digoxin-specific antibodies. The consensus identifies a straightforward approach to dosing immune antibody fragments according to the presence or absence of signs of life-threatening toxicity. Supportive measures and management of specific signs of toxicity are also covered.

Identifiants

pubmed: 37650725
doi: 10.1097/MEJ.0000000000001065
pii: 00063110-202312000-00007
pmc: PMC10599802
doi:

Substances chimiques

Digoxin 73K4184T59

Types de publication

Review Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

395-401

Informations de copyright

Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.

Références

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Auteurs

Paul Andrews (P)

Torbay Hospital, Torbay and South Devon NHS Foundation Trust, Torquay, Devon, UK.

Kurt Anseeuw (K)

Department of Emergency Medicine, ZNA Stuivenberg, Antwerp, Belgium.

Dipak Kotecha (D)

Institute of Cardiovascular Sciences, University of Birmingham.
University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.

Frédéric Lapostolle (F)

SAMU 93-UF Recherche-Enseignement-Qualité, Inserm, U942, Avicenne Hospital, AP-HP, Paris-13 University, Bobigny, France.

Ruben Thanacoody (R)

Translational and Clinical Research Institute, Newcastle University & NPIS (Newcastle), Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.

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