No impact of a high-fat meal coupled with intermittent hypoxemia on acute kidney injury biomarkers in adults with and without obstructive sleep apnea.
fatty acid-binding proteins
hypoxemia
interleukin-18
kidney injury molecule-1
lipocalin-2
oxygen saturation
Journal
Physiological reports
ISSN: 2051-817X
Titre abrégé: Physiol Rep
Pays: United States
ID NLM: 101607800
Informations de publication
Date de publication:
09 2023
09 2023
Historique:
revised:
04
08
2023
received:
29
05
2023
accepted:
16
08
2023
medline:
4
9
2023
pubmed:
1
9
2023
entrez:
1
9
2023
Statut:
ppublish
Résumé
Obstructive sleep apnea (OSA) is characterized by chronic intermittent hypoxemia, which is associated with progressive loss of kidney function, where postprandial fluctuations in renal physiology may further compromise oxygen supply and kidney function. Therefore, we measured biomarkers of acute kidney injury (AKI) following a high-fat meal with and without intermittent hypoxemia. Eighteen healthy young men (mean age [SD]: 22.7 years [3.1]) and seven middle-aged to older individuals with OSA (54.4 years [6.4]) consumed a high-fat meal during normoxia or intermittent hypoxemia (~15 hypoxic cycles per hour, ~85% oxyhemoglobin saturation) for 6 h. We observed no changes in estimated glomerular filtration rate and plasma concentrations of creatinine, neutrophil gelatinase-associated lipocalin (NGAL), and kidney injury molecule-1 (KIM-1) at any measured time points. In both groups, plasma concentrations of interleukin-18 (IL-18) increased after 6 h during normoxia only (p = 0.033, η
Identifiants
pubmed: 37653582
doi: 10.14814/phy2.15804
pmc: PMC10471792
doi:
Substances chimiques
Biomarkers
0
Creatinine
AYI8EX34EU
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e15804Informations de copyright
© 2023 The Authors. Physiological Reports published by Wiley Periodicals LLC on behalf of The Physiological Society and the American Physiological Society.
Références
Ahmed, S. B., Ronksley, P. E., Hemmelgarn, B. R., Tsai, W. H., Manns, B. J., Tonelli, M., Klarenbach, S. W., Chin, R., Clement, F. M., & Hanly, P. J. (2011). Nocturnal hypoxia and loss of kidney function. PLoS One, 6(4), e19029. Public Library of Science. https://doi.org/10.1371/journal.pone.0019029
Araghi, M. H., Chen, Y.-F., Jagielski, A., Choudhury, S., Banerjee, D., Hussain, S., Thomas, G. N., & Taheri, S. (2013). Effectiveness of lifestyle interventions on obstructive sleep apnea (OSA): Systematic review and meta-analysis. Sleep, 36(10), 1553-1562, 1562A-1562E. https://doi.org/10.5665/sleep.3056
Blass, G., Klemens, C. A., Brands, M. W., Palygin, O., & Staruschenko, A. (2019). Postprandial effects on ENaC-mediated sodium absorption. Scientific Reports, 9, 4296. https://doi.org/10.1038/s41598-019-40639-x
Brezis, M., & Epstein, F. H. (1993). Cellular mechanisms of acute ischemic injury in the kidney. Annual Review of Medicine, 44(1), 27-37. https://doi.org/10.1146/annurev.me.44.020193.000331
Chapman, C. L., Johnson, B. D., Vargas, N. T., Hostler, D., Parker, M. D., & Schlader, Z. J. (2020). Both hyperthermia and dehydration during physical work in the heat contribute to the risk of acute kidney injury. Journal of Applied Physiology, 128(4), 715-728. https://doi.org/10.1152/japplphysiol.00787.2019
Chawla, L. S., Bellomo, R., Bihorac, A., Goldstein, S. L., Siew, E. D., Bagshaw, S. M., Bittleman, D., Cruz, D., Endre, Z., Fitzgerald, R. L., Forni, L., Kane-Gill, S. L., Hoste, E., Koyner, J., Liu, K. D., Macedo, E., Mehta, R., Murray, P., Nadim, M., … Kellum, J. A. (2017). Acute kidney disease and renal recovery: Consensus report of the acute disease quality initiative (ADQI) 16 workgroup. Nature Reviews. Nephrology, 13(4), 241-257. https://doi.org/10.1038/nrneph.2017.2
Cohen, J. (1988). Statistical power analysis for the behavioral sciences (2nd ed.). Routledge. https://doi.org/10.4324/9780203771587
Cruz, D. N., Goh, C. Y., Haase-Fielitz, A., Ronco, C., & Haase, M. (2010). Early biomarkers of renal injury. Congestive Heart Failure, 16(s1), S25-S31. https://doi.org/10.1111/j.1751-7133.2010.00163.x
Dobrosielski, D. A., Papandreou, C., Patil, S. P., & Salas-Salvadó, J. (2017). Diet and exercise in the management of obstructive sleep apnoea and cardiovascular disease risk. European Respiratory Review, 26(144), 160110. https://doi.org/10.1183/16000617.0110-2016
Ejerblad, E., Fored, C. M., Lindblad, P., Fryzek, J., McLaughlin, J. K., & Nyrén, O. (2006). Obesity and risk for chronic renal failure. American Society of Nephrology, 17(6), 1695-1702. https://doi.org/10.1681/ASN.2005060638
Esposito, K., Nappo, F., Giugliano, F., Di Palo, C., Ciotola, M., Barbieri, M., Paolisso, G., & Giugliano, D. (2003). Meal modulation of circulating interleukin 18 and adiponectin concentrations in healthy subjects and in patients with type 2 diabetes mellitus. The American Journal of Clinical Nutrition, 78(6), 1135-1140. https://doi.org/10.1093/ajcn/78.6.1135
Evans, R. G., Goddard, D., Eppel, G. A., & O'Connor, P. M. (2011). Factors that render the kidney susceptible to tissue hypoxia in hypoxemia. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 300(4), R931-R940. https://doi.org/10.1152/ajpregu.00552.2010
Felizardo, R. J. F., da Silva, M. B., Aguiar, C. F., & Câmara, N. O. S. (2014). Obesity in kidney disease: A heavyweight opponent. World Journal of Nephrol, 3(3), 50-63. https://doi.org/10.5527/wjn.v3.i3.50
Fine, L. G., & Norman, J. T. (2008). Chronic hypoxia as a mechanism of progression of chronic kidney diseases: From hypothesis to novel therapeutics. Kidney International, 74(7), 867-872. https://doi.org/10.1038/ki.2008.350
Hanly, P. J., & Ahmed, S. B. (2014). Sleep apnea and the kidney: Is sleep apnea a risk factor for chronic kidney disease? Chest, 146(4), 1114-1122. https://doi.org/10.1378/chest.14-0596
Harris, J. A., & Benedict, F. G. (1918). A biometric study of human basal metabolism. Proceedings of the National Academy of Sciences of the United States of America, 4(12), 370-373.
Hudgel, D. W. (2016). Sleep apnea severity classification-Revisited. Sleep, 39(5), 1165-1166. https://doi.org/10.5665/sleep.5776
Kimmel, P. L., Miller, G., & Mendelson, W. B. (1989). Sleep apnea syndrome in chronic renal disease. The American Journal of Medicine, 86(3), 308-314. https://doi.org/10.1016/0002-9343(89)90301-X
Koga, S., Ikeda, S., Yasunaga, T., Nakata, T., & Maemura, K. (2013). Effects of nasal continuous positive airway pressure on the glomerular filtration rate in patients with obstructive sleep apnea syndrome. Internal Medicine, 52(3), 345-349. https://doi.org/10.2169/internalmedicine.52.8468
Lhuissier, F. J., Canouï-Poitrine, F., & Richalet, J.-P. (2012). Ageing and cardiorespiratory response to hypoxia. The Journal of Physiology, 590(21), 5461-5474. https://doi.org/10.1113/jphysiol.2012.238527
Lin, C.-H., Lurie, R. C., & Lyons, O. D. (2020). Sleep apnea and chronic kidney disease: A state-of-the-art review. Chest, 157(3), 673-685. https://doi.org/10.1016/j.chest.2019.09.004
Lopez-Miranda, J., Williams, C., & Lairon, D. (2007). Dietary, physiological, genetic and pathological influences on postprandial lipid metabolism. British Journal of Nutrition, 98(3), 458-473. https://doi.org/10.1017/S000711450774268X
Louis, M., & Punjabi, N. M. (2009). Effects of acute intermittent hypoxia on glucose metabolism in awake healthy volunteers. Journal of Applied Physiology, 106(5), 1538-1544. https://doi.org/10.1152/japplphysiol.91523.2008
Mahat, B., Chassé, É., Mauger, J.-F., & Imbeault, P. (2016). Effects of acute hypoxia on human adipose tissue lipoprotein lipase activity and lipolysis. Journal of Translational Medicine, 14(1), 212. https://doi.org/10.1186/s12967-016-0965-y
Malhotra, A., Mesarwi, O., Pepin, J.-L., & Owens, R. L. (2020). Endotypes and phenotypes in obstructive sleep apnea. Current Opinion in Pulmonary Medicine, 26(6), 609-614. https://doi.org/10.1097/MCP.0000000000000724
Morin, R., Mauger, J.-F., Amaratunga, R., & Imbeault, P. (2021). The effect of acute intermittent hypoxia on postprandial triglyceride levels in humans: A randomized crossover trial. Journal of Translational Medicine, 19(1), 268. https://doi.org/10.1186/s12967-021-02933-z
Newman, A. B., Nieto, J., Guidry, U., Lind, B., Redline, S., Shahar, E., Pickering, T., & Quan, S. (2001). Relation of sleep-disordered breathing to cardiovascular disease risk factors: The sleep heart health study. American Journal of Epidemiology, 154(1), 50-59. https://doi.org/10.1093/aje/154.1.50
Roach, R. C., Hackett, P. H., Oelz, O., Bärtsch, P., Luks, A. M., MacInnis, M. J., Baillie, J. K., Achatz, E., Albert, E., Andrews, J. S., Anholm, J. D., Ashraf, M. Z., Auerbach, P., Basnyat, B., Beidleman, B. A., Berendsen, R. r., Berger, M. M., Bloch, K. E., Brugger, H., … Zafren, K. (2018). The 2018 Lake Louise acute mountain sickness score. High Altitude Medicine & Biology, 19(1), 4-6. https://doi.org/10.1089/ham.2017.0164
Somers, V. K., Dyken, M. E., Clary, M. P., & Abboud, F. M. (1995). Sympathetic neural mechanisms in obstructive sleep apnea. The Journal of Clinical Investigation, 96(4), 1897-1904. https://doi.org/10.1172/JCI118235
Stanski, N., Menon, S., Goldstein, S. L., & Basu, R. K. (2019). Integration of urinary neutrophil gelatinase-associated lipocalin with serum creatinine delineates acute kidney injury phenotypes in critically ill children. Journal of Critical Care, 53, 1-7. https://doi.org/10.1016/j.jcrc.2019.05.017
Stevens, L. A., Claybon, M. A., Schmid, C. H., Chen, J., Horio, M., Imai, E., Nelson, R. G., Van Deventer, M., Wang, H.-Y., Zuo, L., Zhang, Y. L., & Levey, A. S. (2011). Evaluation of the Chronic Kidney Disease Epidemiology Collaboration equation for estimating the glomerular filtration rate in multiple ethnicities. Kidney International, 79(5), 555-562. https://doi.org/10.1038/ki.2010.462
Stich, V., & Berlan, M. (2004). Physiological regulation of NEFA availability: Lipolysis pathway. Proceedings of the Nutrition Society, 63(2), 369-374. https://doi.org/10.1079/PNS2004350
Szendroedi, J., & Roden, M. (2009). Ectopic lipids and organ function. Current Opinion in Lipidology, 20(1), 50-56. https://doi.org/10.1097/MOL.0b013e328321b3a8
Turnbull, C. D. (2018). Intermittent hypoxia, cardiovascular disease and obstructive sleep apnoea. Journal of Thoracic Disease, 10(Suppl 1), S33-S39. https://doi.org/10.21037/jtd.2017.10.33
Vogel, R. A., Corretti, M. C., & Plotnick, G. D. (1997). Effect of a single high-fat meal on endothelial function in healthy subjects. The American Journal of Cardiology, 79(3), 350-354. https://doi.org/10.1016/S0002-9149(96)00760-6
Voulgaris, A., Marrone, O., Bonsignore, M. R., & Steiropoulos, P. (2019). Chronic kidney disease in patients with obstructive sleep apnea. A narrative review. Sleep Medicine Reviews, 47, 74-89. https://doi.org/10.1016/j.smrv.2019.07.001
Wang, G., Gong, Y., Anderson, J., Sun, D., Minuk, G., Roberts, M. S., & Burczynski, F. J. (2005). Antioxidative function of L-FABP in L-FABP stably transfected Chang liver cells. Hepatology, 42(4), 871-879. https://doi.org/10.1002/hep.20857
Wang, S.-Y., Gao, J., & Zhao, J.-H. (2022). Effects of high altitude on renal physiology and kidney diseases. Frontiers in Physiology, 13, 1-10. https://doi.org/10.3389/fphys.2022.969456
Yu, Y., Mo, H., Zhuo, H., Yu, C., & Liu, Y. (2022). High fat diet induces kidney injury via stimulating Wnt/β-catenin signaling. Frontiers in Medicine, 9, 1-9. https://doi.org/10.3389/fmed.2022.851618