Homologous platelet gel on radiation-induced dermatitis in a patient receiving head and neck radiotherapy plus cetuximab: A case report.
Radiodermatitis
/ etiology
Cetuximab
/ therapeutic use
Antineoplastic Agents, Immunological
/ therapeutic use
Combined Modality Therapy
Humans
Male
Aged
Squamous Cell Carcinoma of Head and Neck
/ drug therapy
Oropharyngeal Neoplasms
/ drug therapy
Blood Platelets
Gels
Complementary Therapies
/ methods
Journal
Medicine
ISSN: 1536-5964
Titre abrégé: Medicine (Baltimore)
Pays: United States
ID NLM: 2985248R
Informations de publication
Date de publication:
25 Aug 2023
25 Aug 2023
Historique:
medline:
4
9
2023
pubmed:
1
9
2023
entrez:
1
9
2023
Statut:
ppublish
Résumé
Acute radiodermatitis is a significant complication of cancer radiotherapy, and platelet-based therapies are emerging as potential new treatments. In this report, we present the case of a patient with head and neck cancer undergoing radiotherapy combined with the monoclonal antibody cetuximab. After 4 weeks of this treatment, the patient developed cutaneous radiation dermatitis. Despite receiving standard treatment with corticosteroids and emollient cream, the lesion did not improve. cutaneous radiation dermatitis on head and neck cancer patient. Topical application of platelet gel was initiated on the wound. From the second week of radiotherapy to the 4th week, homologous platelet-rich plasma was applied on the dermatitis using a bandage, 4 times a day. The topical treatment with homologous platelet gel resulted in complete healing of the radiodermatitis, including restoration of the epidermis, reepithelialization, and reduction in associated pain. homologous platelet gel might be an alternative to standard treatment of radiation dermatitis.
Identifiants
pubmed: 37653754
doi: 10.1097/MD.0000000000034779
pii: 00005792-202308250-00026
pmc: PMC10470763
doi:
Substances chimiques
Cetuximab
PQX0D8J21J
Antineoplastic Agents, Immunological
0
Gels
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e34779Informations de copyright
Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.
Déclaration de conflit d'intérêts
The authors have no funding and conflicts of interest to disclose.
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