Brazilian cerrado antioxidant bocaiúva chemotherapy side-effects macaúba oxidative stress

Journal

Frontiers in pharmacology
ISSN: 1663-9812
Titre abrégé: Front Pharmacol
Pays: Switzerland
ID NLM: 101548923

Informations de publication

Date de publication:
2023
Historique:
received: 25 05 2023
accepted: 01 08 2023
medline: 1 9 2023
pubmed: 1 9 2023
entrez: 1 9 2023
Statut: epublish

Résumé

Doxorubicin (Dox) is a chemotherapeutic agent widely used in the clinic, whose side effects include cardiotoxicity, associated with decreased antioxidant defenses and increased oxidative stress. The association of Dox with natural antioxidants can extend its use if not interfering with its pharmacological potential. In this study, we aimed to understand the effects and mechanisms of the aqueous extract of

Identifiants

DOI: 10.3389/fphar.2023.1223933 PMID: 37654604 PMC: PMC10466431
pubmed: 37654604
doi: 10.3389/fphar.2023.1223933
pii: 1223933
pmc: PMC10466431
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1223933

Informations de copyright

Copyright © 2023 Monteiro-Alfredo, dos Santos, Antunes, Cunha, da Silva Baldivia, Pires, Marques, Abrantes, Botelho, Monteiro, Gonçalves, Botelho, Paula de Araújo Boleti, Cabral, Oliveira, Lucas dos Santos, Matafome and de Picoli Souza.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

Sci Rep. 2015 Nov 02;5:15798
pubmed: 26522181
Int J Cardiol Heart Vasc. 2016 Mar;10:17-24
pubmed: 27213178
ScientificWorldJournal. 2013 Dec 29;2013:162750
pubmed: 24470791
J Biochem Mol Toxicol. 2018 Feb;32(2):
pubmed: 29315967
Int J Mol Med. 2015 Jul;36(1):53-64
pubmed: 25936432
Oncotarget. 2017 Jun 6;8(23):38022-38043
pubmed: 28410237
Expert Opin Drug Metab Toxicol. 2014 Dec;10(12):1677-90
pubmed: 25339439
J Biochem Mol Toxicol. 2020 Jul;34(7):e22492
pubmed: 32173980
Biomed Pharmacother. 2018 Apr;100:441-447
pubmed: 29475141
J Cell Mol Med. 2019 Sep;23(9):6034-6047
pubmed: 31225944
Basic Clin Pharmacol Toxicol. 2005 Jan;96(1):80-7
pubmed: 15667600
Phytomedicine. 2018 Feb 1;40:125-139
pubmed: 29496165
Eur J Cell Biol. 2016 Jun-Jul;95(6-7):208-18
pubmed: 27083410
Food Nutr Res. 2017 Jul 6;61(1):1344077
pubmed: 28747863
Eur J Pharmacol. 2019 Sep 15;859:172513
pubmed: 31260654
Nutr Cancer. 2016 Aug-Sep;68(6):892-917
pubmed: 27341037
Br J Pharmacol. 2007 Jul;151(6):771-8
pubmed: 17519947
J Ethnopharmacol. 2018 Oct 5;224:202-229
pubmed: 29842962
Oxid Med Cell Longev. 2016;2016:5724973
pubmed: 27313831
Immunol Lett. 2020 Jan;217:56-64
pubmed: 31707054
Drug Metab Rev. 2016 Nov;48(4):541-567
pubmed: 27320238
Life Sci. 2017 Jul 1;180:160-170
pubmed: 28478263
Cell Death Discov. 2015 Nov 23;1:15043
pubmed: 27551472
Oxid Med Cell Longev. 2020 Mar 22;2020:5238650
pubmed: 32256951
Med Hypotheses. 2021 Nov;156:110679
pubmed: 34555619
J Pharm Pharmacol. 2022 Mar 3;74(3):351-359
pubmed: 34562089
Heliyon. 2020 Apr 20;6(4):e03803
pubmed: 32337383
Oxid Med Cell Longev. 2018 Jun 28;2018:2935051
pubmed: 30050650
PLoS One. 2014 Nov 17;9(11):e112748
pubmed: 25402205
Br J Pharmacol. 2006 May;148(1):1-3
pubmed: 16491096
Phytomedicine. 2022 Nov;106:154407
pubmed: 36070662
Biomed Pharmacother. 2019 Apr;112:108637
pubmed: 30798127
J Nutr Biochem. 2020 Nov;85:108428
pubmed: 32679443
Pharmacol Res. 2020 Jan;151:104542
pubmed: 31730804
Res Pharm Sci. 2020 Feb 20;15(1):87-96
pubmed: 32180820
Pharmacol Res. 2021 Feb;164:105383
pubmed: 33348022
Oxid Med Cell Longev. 2016;2016:9681425
pubmed: 27247703
Life Sci. 2020 Apr 15;247:117439
pubmed: 32070709
J Ethnopharmacol. 2020 May 10;253:112648
pubmed: 32035877
Oxid Med Cell Longev. 2014;2014:748524
pubmed: 24895528
Bioorg Med Chem Lett. 2013 Oct 1;23(19):5307-10
pubmed: 23973213
Nutrients. 2021 Aug 20;13(8):
pubmed: 34445015
Int J Cardiol. 2010 Sep 24;144(1):3-15
pubmed: 20399520
PLoS One. 2016 Dec 1;11(12):e0167531
pubmed: 27907185
Circ Res. 2020 Mar 27;126(7):926-941
pubmed: 32213135
Food Chem Toxicol. 2008 Sep;46(9):3140-6
pubmed: 18652870
Oxid Med Cell Longev. 2019 Apr 28;2019:5736919
pubmed: 31182994

Auteurs

Tamaeh Monteiro-Alfredo (T)

Research Group on Biotechnology and Bioprospection Applied to Metabolism and Cancer (GEBBAM), Federal University of Grande Dourados, Dourados, Brazil.
Faculty of Medicine, Institute of Physiology, University of Coimbra, Coimbra, Portugal.
Faculty of Medicine, Coimbra Institute for Clinical and Biomedical Research (iCBR), University of Coimbra, Coimbra, Portugal.
Clinical Academic Center of Coimbra (CACC), University of Coimbra, Coimbra, Portugal.

Jéssica Maurino Dos Santos (JM)

Research Group on Biotechnology and Bioprospection Applied to Metabolism and Cancer (GEBBAM), Federal University of Grande Dourados, Dourados, Brazil.

Kátia Ávila Antunes (KÁ)

Research Group on Biotechnology and Bioprospection Applied to Metabolism and Cancer (GEBBAM), Federal University of Grande Dourados, Dourados, Brazil.

Janielle Cunha (J)

Research Group on Biotechnology and Bioprospection Applied to Metabolism and Cancer (GEBBAM), Federal University of Grande Dourados, Dourados, Brazil.

Debora da Silva Baldivia (D)

Research Group on Biotechnology and Bioprospection Applied to Metabolism and Cancer (GEBBAM), Federal University of Grande Dourados, Dourados, Brazil.

Ana Salomé Pires (AS)

Clinical Academic Center of Coimbra (CACC), University of Coimbra, Coimbra, Portugal.
Center for Innovative Biomedicine and Biotechnology (CIBB), University Coimbra, Coimbra, Portugal.
Faculty of Medicine, Coimbra Institute for Clinical and Biomedical Research (iCBR) Area of Environment Genetics and Oncobiology (CIMAGO), Institute of Biophysics, University Coimbra, Coimbra, Portugal.

Inês Marques (I)

Clinical Academic Center of Coimbra (CACC), University of Coimbra, Coimbra, Portugal.
Center for Innovative Biomedicine and Biotechnology (CIBB), University Coimbra, Coimbra, Portugal.
Faculty of Medicine, Coimbra Institute for Clinical and Biomedical Research (iCBR) Area of Environment Genetics and Oncobiology (CIMAGO), Institute of Biophysics, University Coimbra, Coimbra, Portugal.

Ana Margarida Abrantes (AM)

Clinical Academic Center of Coimbra (CACC), University of Coimbra, Coimbra, Portugal.
Center for Innovative Biomedicine and Biotechnology (CIBB), University Coimbra, Coimbra, Portugal.
Faculty of Medicine, Coimbra Institute for Clinical and Biomedical Research (iCBR) Area of Environment Genetics and Oncobiology (CIMAGO), Institute of Biophysics, University Coimbra, Coimbra, Portugal.

Maria Filomena Botelho (MF)

Clinical Academic Center of Coimbra (CACC), University of Coimbra, Coimbra, Portugal.
Center for Innovative Biomedicine and Biotechnology (CIBB), University Coimbra, Coimbra, Portugal.
Faculty of Medicine, Coimbra Institute for Clinical and Biomedical Research (iCBR) Area of Environment Genetics and Oncobiology (CIMAGO), Institute of Biophysics, University Coimbra, Coimbra, Portugal.

Lúcia Monteiro (L)

Faculty of Medicine, Coimbra Institute for Clinical and Biomedical Research (iCBR) Area of Environment Genetics and Oncobiology (CIMAGO), Institute of Biophysics, University Coimbra, Coimbra, Portugal.

Ana Cristina Gonçalves (AC)

Faculty of Medicine, Coimbra Institute for Clinical and Biomedical Research (iCBR), University of Coimbra, Coimbra, Portugal.
Clinical Academic Center of Coimbra (CACC), University of Coimbra, Coimbra, Portugal.
Center for Innovative Biomedicine and Biotechnology (CIBB), University Coimbra, Coimbra, Portugal.

Wellington Henrique Botelho (WH)

Research Group on Biotechnology and Bioprospection Applied to Metabolism and Cancer (GEBBAM), Federal University of Grande Dourados, Dourados, Brazil.

Ana Paula de Araújo Boleti (A)

Research Group on Biotechnology and Bioprospection Applied to Metabolism and Cancer (GEBBAM), Federal University of Grande Dourados, Dourados, Brazil.

Célia Cabral (C)

Faculty of Medicine, Coimbra Institute for Clinical and Biomedical Research (iCBR), University of Coimbra, Coimbra, Portugal.
Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal.

Paulo J Oliveira (PJ)

CNC-Center for Neuroscience and Cell Biology, Center for Innovative Biomedicine and Biotechnology, University of Coimbra, Coimbra, Portugal.

Edson Lucas Dos Santos (E)

Research Group on Biotechnology and Bioprospection Applied to Metabolism and Cancer (GEBBAM), Federal University of Grande Dourados, Dourados, Brazil.

Paulo Matafome (P)

Faculty of Medicine, Institute of Physiology, University of Coimbra, Coimbra, Portugal.
Faculty of Medicine, Coimbra Institute for Clinical and Biomedical Research (iCBR), University of Coimbra, Coimbra, Portugal.
Clinical Academic Center of Coimbra (CACC), University of Coimbra, Coimbra, Portugal.
Department of Complementary Sciences, Instituto Politécnico de Coimbra, Coimbra Health School (ESTeSC), Coimbra, Portugal.

Kely de Picoli Souza (K)

Research Group on Biotechnology and Bioprospection Applied to Metabolism and Cancer (GEBBAM), Federal University of Grande Dourados, Dourados, Brazil.

Classifications MeSH